DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1764 and DDAH2

DIOPT Version :9

Sequence 1:	NP_001285198.1	Gene:	CG1764 / 32281	FlyBaseID:	FBgn0030467	Length:	268	Species:	Drosophila melanogaster
Sequence 2:	NP_001289936.1	Gene:	DDAH2 / 23564	HGNCID:	2716	Length:	285	Species:	Homo sapiens

Alignment Length:	272	Identity:	94/272 - (34%)
Similarity:	152/272 - (55%)	Gaps:	22/272 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 THAIVARISDALLEN-----GKFDVQLAKQQHEQYC---TLLRTIGLDVIELPPDDQLPEGVFVE 62
            :||::..:.::|...     |...:.|||.|.|...   .|.:.:||.::||||::.||.|..:.
Human    12 SHALIRGVPESLASGEGAGAGLPALDLAKAQREHGVLGGKLRQRLGLQLLELPPEESLPLGPLLG 76

  Fly    63 NSAVICNGVALIGRSEHPKRQLEAESMAIILKKELDIPVIEIEDPNAQLDGGDVLFTGREFFVGI 127
            ::|||....|||.|...|.|:.|.:.:...| ::|.:.::||.|.||.|||.||||||||||||:
Human    77 DTAVIQGDTALITRPWSPARRPEVDGVRKAL-QDLGLRIVEIGDENATLDGTDVLFTGREFFVGL 140

  Fly   128 SSFTNEEGARAVAMAYPEYPVTPIRVNGTKRLKYYVTMAGPEVLCVSSSPTCQEIVKRMEREAIC 192
            |.:||..||..||..:.::.|:.:.|:|...|:....|.||..:...||...|:.|:.|   |:.
Human   141 SKWTNHRGAEIVADTFRDFAVSTVPVSGPSHLRGLCGMGGPRTVVAGSSDAAQKAVRAM---AVL 202

  Fly   193 T---YQKLTLPEESAANMLYIN----GT---IVHRSPTEIPEAYKTLKEKIDIPTRNINISEFSQ 247
            |   |..||||:::||:.|::.    |.   ::||...::|.:.:.|::..|:....::.||..:
Human   203 TDHPYASLTLPDDAAADCLFLRPGLPGVPPFLLHRGGGDLPNSQEALQKLSDVTLVPVSCSELEK 267

  Fly   248 YSSGLTSSCLLL 259
            ..:||:|.||:|
Human   268 AGAGLSSLCLVL 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1764	NP_001285198.1	Amidinotransf	24..>149	CDD:302778	54/127 (43%)
DDAH2	NP_001289936.1	Amidinotransf	<62..277	CDD:418538	79/218 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149196
Domainoid	1	1.000	113	1.000	Domainoid score	I6132
eggNOG	1	0.900	-	-		E1_COG1834
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I3983
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56587
OrthoDB	1	1.010	-	-		D1469762at2759
OrthoFinder	1	1.000	-	-		FOG0004837
OrthoInspector	1	1.000	-	-		otm40753
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12737
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5737
SonicParanoid	1	1.000	-	-		X4029
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.900