DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15743 and bpnt2

DIOPT Version :9

Sequence 1:	NP_001259511.1	Gene:	CG15743 / 32279	FlyBaseID:	FBgn0030465	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_001032657.1	Gene:	bpnt2 / 641570	ZFINID:	ZDB-GENE-051127-23	Length:	341	Species:	Danio rerio

Alignment Length:	354	Identity:	140/354 - (39%)
Similarity:	195/354 - (55%)	Gaps:	37/354 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 IRINRLPATIVAILLTFVLVYFLNFHQEERPAIYGMLRSENPSRVNLRKMLIAAIQAAQRGGLEV 75
            ||::.|...:..:|...|:.:........|.|.:...|:     |:||::|..:|.||.:||.||
Zfish     6 IRLSPLGIAVFCLLGVGVIYHLYAGVLSSRLAFFRQKRT-----VDLRELLALSIDAAVQGGREV 65

  Fly    76 LDVARSRQLKERSKGKTDEGVNDPFTDADGRSHCVMKQGLQRIFPRVQIFSEEDKEHCKQAHGYD 140
            ..:.....|:|:|||||.||.::.:|..|..||..|...::..||.:|:.||   ||. .|.|
Zfish    66 KRIREDNTLEEKSKGKTKEGASEKYTLGDLNSHRKMYYLIKNTFPNIQVNSE---EHA-NAEG-- 124

  Fly   141 LDPTVLHETAQIPD---------VTVNAQDVTVWVDPLDATKEFTEELYEYVTTMVCVAVAGRPI 196
             :.||.  |..||:         ..:.|:.:|||:||||||:|:||.|.:||||||||||.|.|:
Zfish   125 -EATVW--TRMIPEDILAKVSGGKEIPAEKITVWIDPLDATQEYTENLLKYVTTMVCVAVDGEPV 186

  Fly   197 IGVIHSPFNGQTAWAWVGNSMSEYLSNLHPQHSPNNQAPIITVSRSHTAGAKDLARGIFGENVSL 261
            |||||.||.|.|.|.:||..     ||:.|:.|.|..:|.:.|||||....|...:..||.|..:
Zfish   187 IGVIHKPFTGYTVWGFVGEG-----SNVAPRDSYNTNSPKVIVSRSHAGKVKSFVQTAFGNNTEI 246

  Fly   262 LTAAGAGYKVLQVV------ANNATAYLHTSKIKKWDICAGDAILHALGGTMTTLNDQLINYGPE 320
            :.|.|||||.|.::      ...|..|:|.:.|||||||||||||.:|||.||||..:.|:|...
Zfish   247 IPAGGAGYKALALLNPTDDKQETADIYIHVTYIKKWDICAGDAILKSLGGQMTTLKGEQIDYSGL 311

  Fly   321 ESPVNTEGLLATLE-QHDEYMDKLSKYRE 348
            |.  |..||||::: .|...:.:|..:.:
Zfish   312 EG--NKGGLLASMKVDHKALVKRLPLWED 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15743	NP_001259511.1	IPPase	59..342	CDD:238818	128/298 (43%)
bpnt2	NP_001032657.1	IPPase	46..332	CDD:238818	130/301 (43%)
bpnt2	NP_001032657.1	Substrate binding. /evidence=ECO:0000250	159..162		2/2 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596022
Domainoid	1	1.000	219	1.000	Domainoid score	I2583
eggNOG	1	0.900	-	-		E1_COG1218
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9852
Inparanoid	1	1.050	222	1.000	Inparanoid score	I3516
OMA	1	1.010	-	-		QHG48614
OrthoDB	1	1.010	-	-		D1096950at2759
OrthoFinder	1	1.000	-	-		FOG0007321
OrthoInspector	1	1.000	-	-		oto40213
orthoMCL	1	0.900	-	-		OOG6_107724
Panther	1	1.100	-	-	LDO	PTHR43028
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4434
SonicParanoid	1	1.000	-	-		X5433
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800