Protein Alignment CG15743 and INPP1

DIOPT Version :9

• Sequence 1: NP_001259511.1
• Gene: CG15743 / 32279
• FlyBaseID: FBgn0030465
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_001122400.1
• Gene: INPP1 / 3628
• HGNCID: 6071
• Length: 399
• Species: Homo sapiens
• Alignment Length: 395
• Identity: 103/395 - (26%)
• Similarity: 159/395 - (40%)
• Gaps: 124/395 - (31%)

  Fly    57 LRKMLIAAIQAAQRGGLEVLDVARS-RQ--------LKERSKGKTDEGVNDPF-TDADGRSHCVM 111
            ||::|..:.:||        ::||: ||        ::|:.:|:.::.....| |.||.....|:
Human     5 LRELLCVSEKAA--------NIARACRQQEALFQLLIEEKKEGEKNKKFAVDFKTLADVLVQEVI 61

  Fly   112 KQGLQRIFPRVQ--IFSEEDKEH------------C-----------KQAHGYDLD----PTVLH 147
            ||.::..||.::  ||.||..|.            |           |..:|..:.    ..|:|
Human    62 KQNMENKFPGLEKNIFGEESNEFTNDWGEKITLRLCSTEEETAELLSKVLNGNKVASEALARVVH 126

  Fly   148 ETAQIPDVTVNAQDVTV-------WVDPLDATKEFTEELYEYV--------------TTMVCVAV 191
            :.....|.|:::.::.|       ||||:|:|       |:|:              ..:.||.:
Human   127 QDVAFTDPTLDSTEINVPQDILGIWVDPIDST-------YQYIKGSADIKSNQGIFPCGLQCVTI 184

  Fly   192 --------AGRPIIGVIHSPF----------NGQTAW--AWVGNSMSEYL--------SNLHPQH 228
                    .|.|::|||:.||          .||..|  :::|.:|....        |..|..:
Human   185 LIGVYDIQTGVPLMGVINQPFVSRDPNTLRWKGQCYWGLSYMGTNMHSLQLTISRRNGSETHTGN 249

  Fly   229 -------SPNNQAPIITVSRSHTAGAKDLARGIFGENVSLLTAAGAGYKVLQVVANNATAYLHTS 286
                   ||:..| :|:.|...|..|. |:| :.|:.:  ..|||||||.|.||......|:.:.
Human   250 TGSEAAFSPSFSA-VISTSEKETIKAA-LSR-VCGDRI--FGAAGAGYKSLCVVQGLVDIYIFSE 309

  Fly   287 KIK-KWDICAGDAILHALGGTMTTLNDQLINYGPEESPVNTEGL-LATLEQHDEYMDKLSKYREA 349
            ... |||.||..|||.|:||.:..|.:.|     |.:|  ..|| |..|..|.|........|.|
Human   310 DTTFKWDSCAAHAILRAMGGGIVDLKECL-----ERNP--ETGLDLPQLVYHVENEGAAGVDRWA 367

  Fly   350 HNGKL 354
            :.|.|
Human   368 NKGGL 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15743	NP_001259511.1	IPPase	59..342	CDD:238818	97/379 (26%)
INPP1	NP_001122400.1	IPPase	4..387	CDD:238818	103/395 (26%)
		Substrate binding. /evidence=ECO:0000250	155..158		1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1218
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1096950at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820