Protein Alignment HDAC4 and Sirt7

DIOPT Version :9

• Sequence 1: NP_001259507.1
• Gene: HDAC4 / 32278
• FlyBaseID: FBgn0041210
• Length: 1269
• Species: Drosophila melanogaster
• Sequence 2: NP_651664.2
• Gene: Sirt7 / 43433
• FlyBaseID: FBgn0039631
• Length: 771
• Species: Drosophila melanogaster
• Alignment Length: 389
• Identity: 74/389 - (19%)
• Similarity: 128/389 - (32%)
• Gaps: 85/389 - (21%)

  Fly   595 LGHPMLTGAVQLNVVQTHYENSEAERQAYEHQVVNQKVRQTVLTRSGAAAAAAAAAGVSVVREAQ 659
            :|...|:.|   |...||....|..|:...|.||:|......| |||             :....
  Fly   159 IGEHDLSSA---NPTYTHMALYELHRRRLLHHVVSQNCDGLHL-RSG-------------LPRNS 206

  Fly   660 LKEEDDDSAAEVMDLTDKKKPPKTVL----------------TSTIATSTSQNLPEALAAAAAAA 708
            |.|...:...||.    |...|.:|.                |..:....|:.|.:.:.......
  Fly   207 LSEIHGNMYVEVC----KNCRPNSVYWRQFDTTEMTARYCHKTHRLCHRCSEPLYDTIVHFGERG 267

  Fly   709 AYRAPHNASSNSASATKSGIKLRDQEYLQQQREQLLLLQQE---EELAKSLMRPLSRTLSSPLVP 770
            ..:.|.|.:..:|:|.::.:.|.....|:..::...|.|.:   .:.||..:..|..|....:..
  Fly   268 NVKWPLNWAGATANAQRADVILCLGSSLKVLKKYTWLWQMDRPARQRAKICVVNLQWTPKDAIAS 332

  Fly   771 LGPHG-----LSQIPDTGQQPAPIATSSSADHIPPVNLSLPHRQHRQLMSTLYASQLRNHQPSAS 830
            :..:|     ::|:......|.|:.|..........:|.:|...|     ||....|:|    |.
  Fly   333 IKINGKCDQVMAQLMHLLHIPVPVYTKEKDPIFAHASLLMPEELH-----TLTQPLLKN----AD 388

  Fly   831 GSPPHKVTTGLAYDPLMLKHSCIC---------GDNAQHPEHSGRLQSVWARLNETDLVKRCDRL 886
            .......||....|..:...||..         |...:.|..:||      |: :|:|..| .:.
  Fly   389 EEEAFTTTTEETQDSTISSESCSFNYSDLPIGKGPRIRTPIKNGR------RV-KTNLELR-QKF 445

  Fly   887 RARKATQEELQTVHTEAHAMLFGSNQCQLSRPKLENTL----SASFVRLSCGGLGVDLDTTWNE 946
            :......||::..|.:.:    |..:.:.....||:::    .....:|.|.      ||.:.:
  Fly   446 KTLNGQDEEIKVEHVKTN----GEVKTEKDLITLESSIKIETEVKLEKLECS------DTNFQQ 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC4	NP_001259507.1	iSH2_PI3K_IA_R	43..>87	CDD:304922
		HDAC_classIIa	837..1211	CDD:212544	23/123 (19%)
Sirt7	NP_651664.2	SIRT7	124..338	CDD:238701	38/199 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48252
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100