| Sequence 1: | NP_001259507.1 | Gene: | HDAC4 / 32278 | FlyBaseID: | FBgn0041210 | Length: | 1269 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_008765500.1 | Gene: | Hdac4 / 363287 | RGDID: | 619979 | Length: | 1096 | Species: | Rattus norvegicus |
| Alignment Length: | 1345 | Identity: | 461/1345 - (34%) |
|---|---|---|---|
| Similarity: | 657/1345 - (48%) | Gaps: | 373/1345 - (27%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 10 IHDLPSEAGSDERL-LHITPATLTLDFK-------P-HPAV---DIDQQIMELKKSQELQKQRLI 62
Fly 63 NSFQEQSKQMELEHKLQL-EHKYQKQPTNKRFSLELIVIIQFAVNSHGAFQELRNESMVTAAAAA 126
Fly 127 VAQEQHRQQL--HQQQ-QQHQQQQQ-QQQHQQQQQQQQARGRDGMKLKQNCSANASPEVKQILNC 187
Fly 188 FILSRKSQAAAS--NGTTTTSPYRNRGVVKSSS--GESLPAGTVTSAHPYKIPQPPPSLLKYES- 247
Fly 248 -DFPLRKTASEPNL-LKIRLKQSVIERKA-----RIGGPAGARRHERLLQAAQRRQQKNSVLTNC 305
Fly 306 NSTPDSGPNSPPSAAALAVGVVGSRG--SPT--SAPIQEE------NEEGSQYQPGQRSSINDLP 360
Fly 361 LFSSPSLPNISLGRPHLPNSAQAHAQVNAQVAAQAQAQAQAQAQAHAMFAALAAAQGGCGQPGYY 425
Fly 426 NPLGMAFVGRQPAPLAMIPATGIAPQ-QPSPVVRSASATSTSSSQASLVGDVAPPQAHAASTILP 489
Fly 490 SSSSYMQQLGSVAGSGVNLHAAAVAAAAAAAAAAGSLPPTNSHGHGHGSHAHPHPHAHGHGHGHG 554
Fly 555 HGIYAGHQHNVPITDAQVAQVHLHKQGHRPLGRTQSAPLPLGHPMLTGAVQLNVVQTHYEN---- 615
Fly 616 ------------------------------SEAERQAYEHQVVNQKVRQTVLTRSGAAAAAAAAA 650
Fly 651 GVSVVREAQLKEEDDDSAAEVMDLTDKKKPPKTVLTSTIATSTSQNLPEALAAAAAAAAYRAPHN 715
Fly 716 ASSNSASATKSGIKLRDQEYL--QQQREQLLLLQQEEELAK-----SLMRPLSRTLSSPLVPLGP 773
Fly 774 HGLSQIPDTGQQPAPIATSSSADHIPPVNLSLPHRQHRQLMSTLYASQLRNHQPSASGSPPHK-- 836
Fly 837 VTTGLAYDPLMLKHSCICGDNAQHPEHSGRLQSVWARLNETDLVKRCDRLRARKATQEELQTVHT 901
Fly 902 EAHAMLFGSNQCQLSRPKLEN-----TLSASFVRLSCGGLGVDLDTTWNEHHTATAARMAAGCVI 961
Fly 962 DLALKTAKGDLRNGFAVVRPPGHHAEANLAMGFCFFNSIAIAAKLLRQRMPEVRRILIVDWDVHH 1026
Fly 1027 GNGTQQAFYQSPDILYLSIHRHDDGNFFPGTGGPTECGSGAGLGFNVNISWSGALNPPLGDAEYI 1091
Fly 1092 AAFRTVVMPIARSFNPDIVLVSSGFDAATGHPAPLGGYHVSPACFGFMTRELLQLANGKVVLALE 1156
Fly 1157 GGYDLAAICDSAQECVRALLGDPAAPIAKAELERPPCQNAINTLQKTIAIQQTHWPCVRMLEHTV 1221
Fly 1222 GLSALETLKVEHDESETINAMAGLSMQSMHRTLSRDDSEEPMDQD 1266 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| HDAC4 | NP_001259507.1 | iSH2_PI3K_IA_R | 43..>87 | CDD:304922 | 18/44 (41%) |
| HDAC_classIIa | 837..1211 | CDD:212544 | 230/378 (61%) | ||
| Hdac4 | XP_008765500.1 | ClassIIa_HDAC4_Gln-rich-N | <99..160 | CDD:197398 | 23/98 (23%) |
| HDAC4 | 661..1069 | CDD:212530 | 244/410 (60%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 454 | 1.000 | Domainoid score | I480 |
| eggNOG | 1 | 0.900 | - | - | E1_COG0123 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 576 | 1.000 | Inparanoid score | I1005 |
| OMA | 1 | 1.010 | - | - | QHG46994 | |
| OrthoDB | 1 | 1.010 | - | - | D119187at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0001001 | |
| OrthoInspector | 1 | 1.000 | - | - | otm46126 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100220 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR48252 |
| Phylome | 1 | 0.910 | - | - | ||
| SonicParanoid | 1 | 1.000 | - | - | X933 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| 13 | 12.840 | |||||