DRSC/TRiP Functional Genomics Resources

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Protein Alignment HDAC4 and Sirt4

DIOPT Version :9

Sequence 1:NP_001259507.1 Gene:HDAC4 / 32278 FlyBaseID:FBgn0041210 Length:1269 Species:Drosophila melanogaster
Sequence 2:NP_572241.2 Gene:Sirt4 / 31480 FlyBaseID:FBgn0029783 Length:312 Species:Drosophila melanogaster


Alignment Length:89 Identity:23/89 - (25%)
Similarity:37/89 - (41%) Gaps:12/89 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly   554 GHGIYAGHQHNVPITDAQVAQVHLHKQGHRPLGRTQSAPLPLGHPMLTGAVQLNVVQTHYENSEA 618
            |.|:||...|. |:.       |:.......:.:...|...:|.|..: |.|.|.  ||:..:..
  Fly    69 GVGLYARSNHK-PVQ-------HMEFVKSSAVRKRYWARNFVGWPKFS-ATQPNA--THHALARF 122

  Fly   619 ERQAYEHQVVNQKVRQTVLTRSGA 642
            ||:.....||.|.| ..:.|::|:
  Fly   123 EREERVQAVVTQNV-DRLHTKAGS 145

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HDAC4NP_001259507.1 iSH2_PI3K_IA_R 43..>87 CDD:304922
HDAC_classIIa 837..1211 CDD:212544
Sirt4NP_572241.2 SIRT4 38..299 CDD:238700 23/89 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR48252
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

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