Protein Alignment HDAC4 and clr6

DIOPT Version :9

• Sequence 1: NP_001259507.1
• Gene: HDAC4 / 32278
• FlyBaseID: FBgn0041210
• Length: 1269
• Species: Drosophila melanogaster
• Sequence 2: NP_595333.1
• Gene: clr6 / 2540368
• PomBaseID: SPBC36.05c
• Length: 405
• Species: Schizosaccharomyces pombe
• Alignment Length: 325
• Identity: 81/325 - (24%)
• Similarity: 135/325 - (41%)
• Gaps: 72/325 - (22%)

  Fly   859 QHPEHSGRLQSVWARLNETDLVKRCDRLRARKATQEELQTVHT------------------EAHA 905
            |||....|::.|...:...:|.::.:.:...:||:.::...||                  :.|.
pombe    24 QHPMKPHRVRMVHNLVVNYNLYEKLNVITPVRATRNDMTRCHTDEYIEFLWRVTPDTMEKFQPHQ 88

  Fly   906 MLFG-SNQCQLSRPKLENTLSASFVRLSCGGLGVDLDTTWNEHHTATAARMAAGCVIDLALKTAK 969
            :.|. .:.|.:.....|      |..:|.|| .:......|..:...|...|.|.
pombe    89 LKFNVGDDCPVFDGLYE------FCSISAGG-SIGAAQELNSGNAEIAINWAGGL---------- 136

  Fly   970 GDLRNGFAVVRPPGHHAEANLAMGFCFFNSIAIAA-KLLRQRMPEVRRILIVDWDVHHGNGTQQA 1033
                          |||:...|.|||:.|.||:|| :||:..    :|:|.:|.|||||:|.::.
pombe   137 --------------HHAKKREASGFCYVNDIALAALELLKYH----QRVLYIDIDVHHGDGVEEF 183

  Fly  1034 FYQSPDILYLSIHRHDDGNFFPGTGGPTECGSGAGLGFNVNISWSGALNPPLGDAEYIAAFRTVV 1098
            ||.:..::..|.|:.  |.:|||||...:.|.|.|..:.||:    .|...:.|..|.:.|:.|:
pombe   184 FYTTDRVMTCSFHKF--GEYFPGTGHIKDTGIGTGKNYAVNV----PLRDGIDDESYESVFKPVI 242

  Fly  1099 MPIARSFNPDIVLVSSGFDAATGHPAPLGGYHVS----PACFGFMTRELLQLANGKVVLALEGGY 1159
            ..|.:.|.|:.|::..|.|:..|.  .||.:::|    ..|..|     ::..|..::....|||
pombe   243 SHIMQWFRPEAVILQCGTDSLAGD--RLGCFNLSMKGHSMCVDF-----VKSFNLPMICVGGGGY 300

  Fly  1160  1159
            pombe   301  300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC4	NP_001259507.1	iSH2_PI3K_IA_R	43..>87	CDD:304922
		HDAC_classIIa	837..1211	CDD:212544	81/325 (25%)
clr6	NP_595333.1	PTZ00063	5..403	CDD:240251	81/325 (25%)
		RPD3-like	5..379	CDD:212528	81/325 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0123
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810