Protein Alignment HDAC4 and Hdac11

DIOPT Version :9

• Sequence 1: NP_001259507.1
• Gene: HDAC4 / 32278
• FlyBaseID: FBgn0041210
• Length: 1269
• Species: Drosophila melanogaster
• Sequence 2: NP_659168.1
• Gene: Hdac11 / 232232
• MGIID: 2385252
• Length: 347
• Species: Mus musculus
• Alignment Length: 416
• Identity: 95/416 - (22%)
• Similarity: 155/416 - (37%)
• Gaps: 115/416 - (27%)

  Fly   818 YASQLRNHQPSASG----SPPHKVTTGLAYDPLMLKHSCICGDNAQHPEHSGRLQSVWARLNETD 878
            :|:||..|.|....    ||.:.:|              ..|....||..:|:...|...|.|..
Mouse     3 HATQLYQHVPEKRWPIVYSPRYNIT--------------FMGLEKLHPFDAGKWGKVINFLKEEK 53

  Fly   879 LVKRCDRLRARKATQEELQTVH-----------------TEAHAMLFGSN---QCQLSRPKLENT 923
            |:.....:.||:|::|:|..||                 ||...::|..|   |.::.||
Mouse    54 LLSDGMLVEAREASEEDLLVVHTRRYLNELKWSFVVATITEIPPVIFLPNFLVQRKVLRP----- 113

  Fly   924 LSASFVRLSCGGLGVDLDTTWNEHHTATAARMAA--GCVIDLALKTAKGDLRNGFAVVRPPGHHA 986
                 :|...||             |..|.::|.  |..|::.         .||       ||.
Mouse   114 -----LRTQTGG-------------TIMAGKLAVERGWAINVG---------GGF-------HHC 144

  Fly   987 EANLAMGFCFFNSIAIAAKLLRQRMPEVRRILIVDWDVHHGNGTQQAFYQSPDILYLSIH-RHDD 1050
            .::...|||.:..|.:|.|.|.:|:..:.|..|:|.|.|.|||.::.|.....:..:.:: ||
Mouse   145 SSDRGGGFCAYADITLAIKFLFERVEGISRATIIDLDAHQGNGHERDFMGDKRVYIMDVYNRH-- 207

  Fly  1051 GNFFPGTGGPTECGSGAGLGFNVNISWSGALNPPLGDAEYIAAFRTVVMPIARSFNPDIVLVSSG 1115
              .:||.....|     .:...|.:.|.      ..|.||:......|....:...||:|:.::|
Mouse   208 --IYPGDRFAKE-----AIRRKVELEWG------TEDEEYLEKVERNVRRSLQEHLPDVVVYNAG 259

  Fly  1116 FDAATGHPAPLGGYHVSPACFGFMTRE-----LLQLANGKVVLALEGGYDLAAICDSAQECVRAL 1175
            .|...|.  .|||..:|||  |.:.|:     :::..:..:::...|||         |:....:
Mouse   260 TDVLEGD--RLGGLSISPA--GIVKRDEVVFRVVRAHDIPILMVTSGGY---------QKRTARI 311

  Fly  1176 LGDPAAPIAKAELERP--PCQNAINT 1199
            :.|....:....|..|  ||.:|.|:
Mouse   312 IADSILNLHDLGLIGPEFPCVSAQNS 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC4	NP_001259507.1	iSH2_PI3K_IA_R	43..>87	CDD:304922
		HDAC_classIIa	837..1211	CDD:212544	88/393 (22%)
Hdac11	NP_659168.1	Histone deacetylase	14..318		84/384 (22%)
		HDAC_classIV	35..319	CDD:212519	80/350 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0123
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900