Protein Alignment HDAC4 and F43G6.4

DIOPT Version :10

• Sequence 1: NP_001259507.1
• Gene: HDAC4 / 32278
• FlyBaseID: FBgn0041210
• Length: 1269
• Species: Drosophila melanogaster
• Sequence 2: NP_496519.2
• Gene: F43G6.4 / 174810
• WormBaseID: WBGene00009657
• Length: 270
• Species: Caenorhabditis elegans
• Alignment Length: 268
• Identity: 55/268 - (20%)
• Similarity: 86/268 - (32%)
• Gaps: 89/268 - (33%)

  Fly   143 HQQQQ-----QQQQHQQQQQQQQARGRDGMKLKQNCSANASPEVKQIL-------NCFILSRKSQ 195
            |.|||     .|...|||.||:.:.|...:...|..|.:.||:.|:::       .|.:.:.|..
 Worm    36 HMQQQYFLNIMQLVQQQQYQQRLSSGGSPVNSDQASSRSESPQTKKLILDEDGCATCSVCTEKVP 100

  Fly   196 AAASNG------------TTTTSPYRNRGVVKSSSGESLPAGTVTSAHPYKIPQPPPSLLKYESD 248
            .|..|.            .|.|...|.|      ..|:.|                        |
 Worm   101 EAEWNSHIELEKERLISYITLTKEKRER------DRENTP------------------------D 135

  Fly   249 FPLRKTASEPNLLKIRLKQSVIERKARIGGPAGARRHERLLQAAQRRQQKNSVLTNCNSTPDSGP 313
            ...:|...|..|.:||..|:  :|::...||...|   ..|....|:....   |..:.:||...
 Worm   136 HFDQKRKRELELQRIRNNQN--KRQSLKRGPQLVR---DCLTPFSRQSNDE---TGSSESPDMKK 192

  Fly   314 NS----------PPSAAALAV-----------------GVVGSRGSPTSAPIQEENEEGSQYQPG 351
            :.          .|.:.|:.:                 .|:.|..||||:..:|:.:..|.....
 Worm   193 DDEFYMKCTTCHQPCSYAIVMSAFDRPKCQICFDLVRAAVLNSAASPTSSATKEDPDHDSSPPAC 257

  Fly   352 QRSSINDL 359
            ::..|.||
 Worm   258 KKMKIEDL 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HDAC4	NP_001259507.1	ClassIIa_HDAC_Gln-rich-N	43..>87	CDD:421006
		HDAC_classIIa	837..1211	CDD:212544
F43G6.4	NP_496519.2	None