Sequence 1: | NP_001259507.1 | Gene: | HDAC4 / 32278 | FlyBaseID: | FBgn0041210 | Length: | 1269 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001123888.1 | Gene: | Hdac6 / 15185 | MGIID: | 1333752 | Length: | 1149 | Species: | Mus musculus |
Alignment Length: | 737 | Identity: | 211/737 - (28%) |
---|---|---|---|
Similarity: | 304/737 - (41%) | Gaps: | 206/737 - (27%) |
- Green bases have known domain annotations that are detailed below.
Fly 534 HGHGS---------------HAHPH----PHAH-------GHGHGHGHGIYAGHQHNVP-----I 567
Fly 568 TDAQVAQVHLH----------------KQGHRPL---GRTQSAPLPLGHPMLTGAVQLNVVQTHY 613
Fly 614 ENSEAERQAYEHQVVNQKVRQTVLTRSGAAAAAAAAAGVSVVREAQLKEEDDDSAAEVMDLTDKK 678
Fly 679 KPPKTVLTSTIATSTSQNLPEALAAAAAAAAYRAPHNASSNSASATKSGIKLRDQEYLQQQREQL 743
Fly 744 LLLQQEEELAKSLMRPLSRTLSSPLVPLGPHGLSQIPDTGQQPAPIATSSSADHIPPVNLSLPHR 808
Fly 809 QHRQLMSTLYASQLRNHQPSASGSPPHKVTTGLAYDPLMLKHSCICGDNAQHPEHSGRLQSVWAR 873
Fly 874 LNETDLVKRCDRLRARKATQEELQTVHTEAHAMLFGSNQCQLSRPKLENTLSASFVRLSCGGLGV 938
Fly 939 DLDTTWNEHHTATAARMAAGCVIDLALKTAKGDLRNGFAVVRPPGHHAEANLAMGFCFFNSIAIA 1003
Fly 1004 AKLLRQRMPEVRRILIVDWDVHHGNGTQQAFYQSPDILYLSIHRHDDGNFFP--GTGGPTECGSG 1066
Fly 1067 AGLGFNVNISWSGALNPPLGDAEYIAAFRTVVMPIARSFNPDIVLVSSGFDAATGHPAPLGGYHV 1131
Fly 1132 SPACFGFMTRELLQLANGKVVLALEGGYDLAAICDSAQECVRALLGDPAAPIAKAELERPPCQNA 1196
Fly 1197 INTLQKTIAIQQTHWPCVRMLE 1218 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
HDAC4 | NP_001259507.1 | iSH2_PI3K_IA_R | 43..>87 | CDD:304922 | |
HDAC_classIIa | 837..1211 | CDD:212544 | 155/375 (41%) | ||
Hdac6 | NP_001123888.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..61 | ||
Histone deacetylase 1 | 87..403 | 34/176 (19%) | |||
Arginase_HDAC | 98..434 | CDD:418394 | 43/252 (17%) | ||
Histone deacetylase 2 | 481..799 | 144/338 (43%) | |||
HDAC6-dom2 | 484..834 | CDD:212527 | 153/373 (41%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 954..975 | ||||
zf-UBP | 1067..1129 | CDD:396634 | |||
Ubiquitin binding. /evidence=ECO:0000250|UniProtKB:Q9UBN7 | 1088..1090 | ||||
Ubiquitin binding. /evidence=ECO:0000250|UniProtKB:Q9UBN7 | 1116..1123 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG0123 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 1 | 1.010 | - | - | D1484694at2759 | |
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 1 | 0.900 | - | - | OOG6_100220 | |
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R2991 |
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 1 | 1.000 | - | - | ||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
6 | 5.750 |