| Sequence 1: | NP_001259507.1 | Gene: | HDAC4 / 32278 | FlyBaseID: | FBgn0041210 | Length: | 1269 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_017169770.1 | Gene: | Hdac5 / 15184 | MGIID: | 1333784 | Length: | 1133 | Species: | Mus musculus |
| Alignment Length: | 1341 | Identity: | 449/1341 - (33%) |
|---|---|---|---|
| Similarity: | 647/1341 - (48%) | Gaps: | 332/1341 - (24%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 7 RIPIHDLPSEAGSDERLLHITPATL---------------TLDFKPHPAV---DIDQQIMELKKS 53
Fly 54 QELQKQRLINSFQEQSKQMELEHKLQLEHKYQKQPTNKRFSLELIVIIQFAVNSHGAFQELRNES 118
Fly 119 MVTAAAAAVAQEQHRQQLHQQQQQHQQQQQQQQHQQQQQQQQARGRDGMKLKQNCSANASPEVKQ 183
Fly 184 ILNCFILSRKSQAAASNGTTTTSPY-------RNRGVVKSSSGESLPAGTVTSAHPYKIPQPPPS 241
Fly 242 LLKYES--DFPLRKTASEPNL-LKIRLKQSVIERKARIGGPAGARRHERLLQAAQRRQQK----- 298
Fly 299 NSVLTNCNSTPDSGPNSPPSAAALAVGVVGSRGSPTSAPIQEENEEGSQYQPGQR-----SSIND 358
Fly 359 LPLFSSPSLPNISLGRPHLPNSAQAHAQVNAQVAAQAQAQAQAQAQAHAMFAALAAAQGGCGQPG 423
Fly 424 YYNPLGMAFVGRQPAPLAMIPATGIAPQQPSPVVRSASATSTSSSQASLVGDVAP---------- 478
Fly 479 ---PQAHAASTILPSSSSYMQQLGSVAGSGVNLHAAAVAA----AAAAAAAAGSLPPTNSHGHGH 536
Fly 537 GSHAHPHPHAHGHGHGHGHGIYAGHQHNVPITDAQVAQVHLHKQGHRPLGRTQSAPLPLGHPMLT 601
Fly 602 GAVQLNVVQTHYENSEAERQAYEHQVVNQKVRQTVLTRSGAAAAAAAAAGVSVVREAQLKEEDDD 666
Fly 667 SAAEVMDLTDKKKPPKTVLTSTIATSTSQNLPEALAAAAAAAAYRAPHNASSNSASATKSGIKLR 731
Fly 732 DQEYLQQQREQLLLLQQEEELAKSLMRPLSRTLSSPLVPLGPHGLSQIPDTGQQPAPI-ATSSSA 795
Fly 796 DHIPPVN-----LSLPHRQHRQLMSTLYASQLRNHQPSASGS----------PPHKVTTGLAYDP 845
Fly 846 LMLKHSCICGDNAQHPEHSGRLQSVWARLNETDLVKRCDRLRARKATQEELQTVHTEAHAMLFGS 910
Fly 911 ---NQCQLSRPKLENTLSAS-FVRLSCGGLGVDLDTTWNEHHTATAARMAAGCVIDLALKTAKGD 971
Fly 972 LRNGFAVVRPPGHHAEANLAMGFCFFNSIAIAAKLLRQRMPEVRRILIVDWDVHHGNGTQQAFYQ 1036
Fly 1037 SPDILYLSIHRHDDGNFFPGTGGPTECGSGAGLGFNVNISWSGALNPPLGDAEYIAAFRTVVMPI 1101
Fly 1102 ARSFNPDIVLVSSGFDAATGHPAPLGGYHVSPACFGFMTRELLQLANGKVVLALEGGYDLAAICD 1166
Fly 1167 SAQECVRALLGDPAAPIAKAELERPPCQNAINTLQKTIAIQQTHWPCVRMLEHTVGLSALETLKV 1231
Fly 1232 EHDESETINAMAGLSM--QSMHRTLSRDDS----EEPMDQD 1266 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| HDAC4 | NP_001259507.1 | iSH2_PI3K_IA_R | 43..>87 | CDD:304922 | 16/43 (37%) |
| HDAC_classIIa | 837..1211 | CDD:212544 | 218/377 (58%) | ||
| Hdac5 | XP_017169770.1 | ClassIIa_HDAC_Gln-rich-N | 87..174 | CDD:391182 | 33/124 (27%) |
| HDAC5 | 690..1109 | CDD:212531 | 235/419 (56%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 453 | 1.000 | Domainoid score | I499 |
| eggNOG | 1 | 0.900 | - | - | E1_COG0123 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 557 | 1.000 | Inparanoid score | I1103 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG46994 | |
| OrthoDB | 1 | 1.010 | - | - | D119187at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0001001 | |
| OrthoInspector | 1 | 1.000 | - | - | otm44037 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100220 | |
| Panther | 1 | 1.100 | - | - | O | PTHR48252 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R2991 |
| SonicParanoid | 1 | 1.000 | - | - | X933 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| 14 | 13.870 | |||||