| Sequence 1: | NP_001259507.1 | Gene: | HDAC4 / 32278 | FlyBaseID: | FBgn0041210 | Length: | 1269 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_310688.5 | Gene: | AgaP_AGAP000410 / 1271834 | VectorBaseID: | AGAP000410 | Length: | 1004 | Species: | Anopheles gambiae |
| Alignment Length: | 1297 | Identity: | 592/1297 - (45%) |
|---|---|---|---|
| Similarity: | 708/1297 - (54%) | Gaps: | 394/1297 - (30%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 39 PAVDIDQQIMELKKSQELQKQRLINSFQEQSKQMELEHKLQLEHKYQKQPTNKRFSLELIVIIQF 103
Fly 104 AVNSHGAFQELRNESMVTAAAAAVAQEQHRQQLHQQQQQHQQQQQQQQHQQQQQQQQARGRDGMK 168
Fly 169 LKQ--NCSANASPEVKQILNCFILSRKSQAAASNGTTTTSPYRNRGVVKSSSGESLPAGTV---T 228
Fly 229 SAHPYKIPQPPPSLLKYESDFPLRKTASEPNLLKIRLKQSVIERKARIGGPAGARRHERLLQAAQ 293
Fly 294 RRQQKNSVL--TNCN-----STPDSGPNSPPSAAALAVGVVGSRGSPTSAPIQEENEEGSQYQPG 351
Fly 352 QRSSINDLPLFSSPSLPNISLGRPHLPNSAQAHAQVNAQVAAQAQAQAQAQAQAHAMFAALAAAQ 416
Fly 417 GGCGQPGYYNPLGMAFVGRQPAPLAMIPATGIAPQQPSPVVRSASATSTSSSQASLVGDVAPPQA 481
Fly 482 HAASTILPSSSSYMQQLGSVAGSGVNLHAAAVAAAAAAAAAAGSLPPTNSHGHGHGSHAHPHPHA 546
Fly 547 HGHGHGHGHGIYAGHQHNVPITDAQVAQVHLHKQGHRPLGRTQSAPLPLGHPMLTGAVQLNVVQT 611
Fly 612 HYENSEAERQAYE-HQVVNQKVRQTVLTRSGAAAAAAAAAGVSVVREAQLKEEDDDSAAEVMDLT 675
Fly 676 DKKKPPKTVLTSTIATSTSQNLPEALAAAAAAAAYRAPHNASSNSASATKSGIKLRDQEYLQQQR 740
Fly 741 EQLLLLQQ-----EEEL-------------------------------------AKSLMRPLSRT 763
Fly 764 LSSPLVPLGPHG--------LSQIPDTGQQPAPIATSSSADHIPPVNLSLPHRQHRQLMSTLYAS 820
Fly 821 QLRNHQPSASGSPPHKVTTGLAYDPLMLKHSCICGDNAQHPEHSGRLQSVWARLNETDLVKRCDR 885
Fly 886 LRARKATQEELQTVHTEAHAMLFGSNQCQLSRPKLENTLSASFVRLSCGGLGVDLDTTWNEHHTA 950
Fly 951 TAARMAAGCVIDLALKTAKGDLRNGFAVVRPPGHHAEANLAMGFCFFNSIAIAAKLLRQRMP-EV 1014
Fly 1015 RRILIVDWDVHHGNGTQQAFYQSPDILYLSIHRHDDGNFFPGTGGPTECGSGAGLGFNVNISWSG 1079
Fly 1080 ALNPPLGDAEYIAAFRTVVMPIARSFNPDIVLVSSGFDAATGHPAPLGGYHVSPACFGFMTRELL 1144
Fly 1145 QLANGKVVLALEGGYDLAAICDSAQECVRALLGDPAAPIAKAELERPPCQNAINTLQKTIAIQQT 1209
Fly 1210 HWPCVRMLEHTVGLSALETLKVEHDESETINAMAGLSMQSMHRT--LSRDDSEEPMDQDETK 1269 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| HDAC4 | NP_001259507.1 | iSH2_PI3K_IA_R | 43..>87 | CDD:304922 | 24/43 (56%) |
| HDAC_classIIa | 837..1211 | CDD:212544 | 275/374 (74%) | ||
| AgaP_AGAP000410 | XP_310688.5 | iSH2_PI3K_IA_R | 39..111 | CDD:304922 | 37/130 (28%) |
| tolA_full | 45..>136 | CDD:274303 | 47/150 (31%) | ||
| Arginase_HDAC | 587..944 | CDD:302587 | 275/373 (74%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Domainoid | 1 | 1.000 | 477 | 1.000 | Domainoid score | I1406 |
| eggNOG | 1 | 0.900 | - | - | E1_COG0123 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H136569 | |
| Inparanoid | 1 | 1.050 | 704 | 1.000 | Inparanoid score | I1835 |
| OMA | 1 | 1.010 | - | - | QHG46994 | |
| OrthoDB | 1 | 1.010 | - | - | D119187at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0001001 | |
| OrthoInspector | 1 | 1.000 | - | - | otm51057 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR48252 |
| Phylome | 1 | 0.910 | - | - | ||
| SonicParanoid | 1 | 1.000 | - | - | X933 | |
| TreeFam | 1 | 0.960 | - | - | ||
| 13 | 12.940 | |||||