| Sequence 1: | NP_001259507.1 | Gene: | HDAC4 / 32278 | FlyBaseID: | FBgn0041210 | Length: | 1269 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_016879477.1 | Gene: | HDAC5 / 10014 | HGNCID: | 14068 | Length: | 1161 | Species: | Homo sapiens |
| Alignment Length: | 1278 | Identity: | 451/1278 - (35%) |
|---|---|---|---|
| Similarity: | 639/1278 - (50%) | Gaps: | 288/1278 - (22%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 43 IDQQIMELKKSQELQKQRLINSFQEQSKQMELEHKLQLE-HKYQKQPTNKRFSLELIVIIQFAVN 106
Fly 107 SHGAFQELRNESMVTAAAAAVAQEQHRQQLHQQQQQHQQQQQQQQHQQQQQQQQARGRDGMKLKQ 171
Fly 172 NCSANASPEVKQILNCFILSRKSQAAASNGTTTTSPY-------RNRGVVKSSSGESLPAGTVTS 229
Fly 230 AHPYKIPQPPPSLLKYES--DFPLRKTASEPNL-LKIRLKQSVIERKARIGGPAGARRHERLLQA 291
Fly 292 AQRRQQK--------NSVLTNCNSTPDSGPNSPPSAAALAVGVVGSRGSPTSAPIQEENEEGSQY 348
Fly 349 QPGQR-----SSINDLPLFSSPSLPNISLGRPHLPNSAQAHAQVNAQVAAQAQAQAQAQAQAHAM 408
Fly 409 FAALAAAQGGCGQPGYYNPLGMAFVGRQPAPLAMIPATGIAPQQPSPVVRSASATSTSSSQASLV 473
Fly 474 GDV-APPQAHAASTILPSSSSYMQQLGSVAGSGVNLHAAAVAA----AAAAAAAAGSLPPTNSHG 533
Fly 534 HGHGSHAHPHPHAHGHGHGHGHGIYAGHQHNVPITDAQVAQVHLHKQGHRPLGRTQSAPLPLGHP 598
Fly 599 MLTGAVQLNVVQTHYENSEAERQAYEHQVVNQKVRQTVLTRSGAAAAAAAAAGVSVVREAQLKEE 663
Fly 664 DDDSAAEVMDLTDKKKPPKTVLTSTIATSTSQNLPEALAAAAAAAAYRAPHNASSNSASATKSGI 728
Fly 729 KLRDQEYLQQQREQLLLLQQEE-----ELAKSLMRPLS--RTLSSPLVPLGPHGLSQIPDTGQQP 786
Fly 787 APIATSSSADHIPPVNLSLPHRQHRQLMSTLYASQLRNHQPSASG---SPP-----HKVTTGLAY 843
Fly 844 DPLMLKHSCICGDNAQHPEHSGRLQSVWARLNETDLVKRCDRLRARKATQEELQTVHTEAHAMLF 908
Fly 909 GS---NQCQLSRPKLENTLSAS-FVRLSCGGLGVDLDTTWNEHHTATAARMAAGCVIDLALKTAK 969
Fly 970 GDLRNGFAVVRPPGHHAEANLAMGFCFFNSIAIAAKLLRQRMPEVRRILIVDWDVHHGNGTQQAF 1034
Fly 1035 YQSPDILYLSIHRHDDGNFFPGTGGPTECGSGAGLGFNVNISWSGALNPPLGDAEYIAAFRTVVM 1099
Fly 1100 PIARSFNPDIVLVSSGFDAATGHPAPLGGYHVSPACFGFMTRELLQLANGKVVLALEGGYDLAAI 1164
Fly 1165 CDSAQECVRALLGDPAAPIAKAELERPPCQNAINTLQKTIAIQQTHWPCVRMLEHTVGLSALETL 1229
Fly 1230 KVEHDESETINAMAGLSM--QSMHRTLSRDDS----EEPMDQD 1266 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| HDAC4 | NP_001259507.1 | iSH2_PI3K_IA_R | 43..>87 | CDD:304922 | 17/44 (39%) |
| HDAC_classIIa | 837..1211 | CDD:212544 | 218/377 (58%) | ||
| HDAC5 | XP_016879477.1 | None | |||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 448 | 1.000 | Domainoid score | I516 |
| eggNOG | 1 | 0.900 | - | - | E1_COG0123 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 610 | 1.000 | Inparanoid score | I921 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG46994 | |
| OrthoDB | 1 | 1.010 | - | - | D119187at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0001001 | |
| OrthoInspector | 1 | 1.000 | - | - | otm41987 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100220 | |
| Panther | 1 | 1.100 | - | - | O | PTHR48252 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R2991 |
| SonicParanoid | 1 | 1.000 | - | - | X933 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 15 | 14.870 | |||||