Protein Alignment mew and ItgaPS5

DIOPT Version :9

• Sequence 1: NP_001285196.1
• Gene: mew / 32275
• FlyBaseID: FBgn0004456
• Length: 1243
• Species: Drosophila melanogaster
• Sequence 2: NP_611808.2
• Gene: ItgaPS5 / 37732
• FlyBaseID: FBgn0034880
• Length: 1018
• Species: Drosophila melanogaster
• Alignment Length: 1170
• Identity: 272/1170 - (23%)
• Similarity: 463/1170 - (39%)
• Gaps: 290/1170 - (24%)

  Fly    50 SHFGYSVATHTIGEANGPNKTNCVLVGAPLDQN---RQPNTTHSGALWRCPMTQRFDDCEQVITD 111
            |:||||:..          :...:.||||..|:   .|.:...:||::|||:..  ..|...:.:
  Fly    45 SYFGYSLVI----------RPTSIFVGAPRAQSTLESQGSINETGAVYRCPLAS--GSCSHYVLN 97

  Fly   112 GRRNFDSEILSPPGNDEIKEDQWMGVTVRSNPLQANGSGG-----KVIVCAHRYMYIVRENRYGQ 171
            .:.|              |:.||:|.::         .||     |::|||.|: ::.:...|||
  Fly    98 DKLN--------------KQFQWLGGSM---------DGGTKDTDKLLVCAPRF-FVPKNKNYGQ 138

  Fly   172 --GLCYLLTNDLQFEEVHEPCKGRP----------VQRQHEDYGLCQAGTSAALLDDDT-MVLGS 223
              |:||.         |.:.....|          :..|.|::.:.:.|.||.:.||:: .::|:
  Fly   139 MRGICYW---------VRDTVADTPPLSDVRTISLIPSQAEEHFMLELGLSAHVTDDNSGFLIGA 194

  Fly   224 PGPYTWRGSIWVTQ-----VGGEYLQR--DKTTYYSDHSDLNSPVDKYSYLGMSVTGGRFFGH-- 279
            ||..:|:||:.|.:     ..|.|..:  |...:..:|         ::|:|.:::.|.|..:
  Fly   195 PGVRSWKGSVLVHRGEDLAAQGSYAVKMLDSWDWVKNH---------FTYVGYALSSGYFSSNNR 250

  Fly   280 --MSYAAGAPRSE-GHGQVVIFDKSTDNPIPVHSILDGEQFGSSFGYELATADINGDHRPDLIVA 341
              :.|...||.|. ..|:..|||...:....:| :..|||.|..|||.:...|:|||...|::|:
  Fly   251 TSLLYVTTAPSSVLNTGKAYIFDVVGEIVRKLH-VFHGEQLGEYFGYSVVAEDLNGDGLTDVVVS 314

  Fly   342 APL------YFTKTEGGAVYVYQNIQDTLPMKYTLKLTGPLES--RFGLALANIGDLNKDNCEDL 398
            |||      |    :.||:||:.|.......|..::|  ||.|  |||.:|:.:||:|.|...||
  Fly   315 APLNALGDSY----DVGAIYVFINKGLFKFEKKIIRL--PLSSGARFGSSLSKVGDINHDGYNDL 373

  Fly   399 AVGAPYEGNGVVYIYLGSSQGLNSKPAQKIQASELGGTIPNGQP----IRTFGISISGNTDLDDN 459
            |||||:.|||.|:|:|||..||..:|:|::.|       |:.:|    ...||..:|..:|:|.|
  Fly   374 AVGAPFAGNGAVFIFLGSEHGLRDEPSQRLDA-------PSREPGPYGAHMFGQGLSRGSDIDGN 431

  Fly   460 SYPDVVIGAFNSSAAVILLARPIISIQTSVQRKELHNMDPNTPGCLDDPASNLTCFTFRACCSIE 524
            .:.|:.|||..:.|..:..|.|::.|..:| |.|...:.|..           ...|..||..:|
  Fly   432 GFNDLAIGAPGAEAVYLYRAYPVVKIHATV-RSESRAIRPEQ-----------ETITVTACYRLE 484

  Fly   525 PYDEKNKELRLAYSVEAETFDHLKKFSRVFFFDRENKRTNVLSRVVRVHTNGRTECQAVTGYIKA 589
            . ..|.::::........|.|.|  ..||.|   ...|||.:|...:...:|.....:|..:.
  Fly   485 T-TSKARQMQQQELTFRMTIDEL--LQRVSF---APMRTNEVSFQAQAGLSGSCRNFSVGVHY-- 541

  Fly   590 NTRDIQTPVRFRLKYSLVEP-PLADSALVRLNPILDQTQAHVDFEGT--FQKDCGDDDLCESNLI 651
             |..|.||:...|.|.|.:. |.:..|......::|..:... ..||  |...|. ..:|.|:|.
  Fly   542 -TGGIFTPIDLELHYELAKKIPHSHEAFCESCAVVDPLEPKY-ATGTLSFMTGCA-AHVCVSDLQ 603

  Fly   652 IRVEPNITESSGNEYTLILDETE-LEVRINVSNLADSAYEAQLFIAHQAGVSYVATKKPTNATCN 715
            :       .|.....:.|....| |.....::|..:.||.||..:...|.:.:  .|.|.|  |.
  Fly   604 L-------SSKDVNSSFIFGSLEVLSFSYEITNSGEPAYVAQFNVTSSARLPF--AKVPGN--CR 657

  Fly   716 SYNTTLVACSL--GNPMLRDTTTFVTIRFQPKGLEPSEKIMLFHIFANTTSKLVGPERPERDLRV 778
            ..:..:: |.|  |..:.|..:..:||.|....|....    ..|.|..:|  .|.::..:|..:
  Fly   658 VRHEVML-CDLNGGRALARGDSESLTIIFDVTQLSGQS----LTIEAAVSS--AGMDQNPKDNTM 715

  Fly   779 NVVRRAKLNFRGWAIPEQSFYSGSSVANSVANTAATDIEGHGPMGMDDVGSQVHHMFTIFNEGPS 843
            :..    ::.|.:|               ..:.:...|:||..:......::|::.:...:.|||
  Fly   716 STT----ISLREYA---------------EIDASGGPIDGHIALKEYPYSAEVNNSYEFKSHGPS 761

  Fly   844 TAPKVQMVIHWPYSLYSDPQSGRPVQYLLYLEQVPTVEVSQGECHVAKEYVNPLNLASGSRENPA 908
            ...::        ::|.|.    |:.|        ||..|.|
  Fly   762 IIDEL--------TVYVDV----PIAY--------TVTGSAG----------------------- 783

  Fly   909 YLSAPAQMRMFPSQSRHSFNKSLIHSQRSY---------YSSSH---RDDHSDDTQSNRNRVRRS 961
                          .:..||.|.:..|.::         |..::   ::...:|:....||.||.
  Fly   784 --------------IKSIFNISSLQMQATHGSELVPIKLYDQTNTLAKEYPLEDSSRRANRKRRE 834

  Fly   962 FLERVTRLERLMYDPESSNAANGKKQDI-----VELDCNKGA-TNCVRIECDILNMPALSEAQVV 1020
            ..:     ::....|:.:.:....|:::     :.|||.:|. |.|||.:..:...|     :..
  Fly   835 LQQ-----DQYAIMPDVNISDILTKENLPANRTLVLDCLRGNWTICVRSQMRVQLKP-----EQP 889

  Fly  1021 VKARLWNSTLVSEYPRVERVRIFSTATAQIPESYGVEVMDHNNIEVETRAYPELRNQQRDTSIPW 1085
            :..|:.....::::.......:..|......|.      |..:|.::....|.:.....:|.:|.
  Fly   890 IDLRISFKVDLNDFVNTFDYLVIFTNVEMFKEG------DSTSIALKRNLKPNVIFNYSETPLPI 948

  Fly  1086 LIIILGIVGGLLLLALVTYVLWKVGFFKRIR------------------PTDPTLSGNLEKMNEE 1132
            ..|||.::.|.|||..:||:|:|:.||||.:                  .||  ..||.|::|.|
  Fly   949 WYIILSLIAGHLLLGAMTYILYKLRFFKRGKKEELKRLLEEHRSETKEPATD--CEGNQEEINVE 1011

  Fly  1133  1132
              Fly  1012  1011

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mew	NP_001285196.1	Int_alpha	48..111	CDD:214549	17/63 (27%)
		Int_alpha	317..368	CDD:214549	19/56 (34%)
		Int_alpha	378..428	CDD:214549	28/51 (55%)
		Int_alpha	446..491	CDD:214549	15/44 (34%)
		Integrin_alpha2	479..1006	CDD:285619	105/550 (19%)
ItgaPS5	NP_611808.2	VCBS	302..375	CDD:338792	30/78 (38%)
		Int_alpha	351..403	CDD:214549	28/51 (55%)
		Int_alpha	417..463	CDD:214549	15/46 (33%)
		Integrin_alpha2	451..836	CDD:337057	95/501 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439841
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D12256at50557
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23220
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950