Protein Alignment mew and itga11

DIOPT Version :9

• Sequence 1: NP_001285196.1
• Gene: mew / 32275
• FlyBaseID: FBgn0004456
• Length: 1243
• Species: Drosophila melanogaster
• Sequence 2: XP_017947982.1
• Gene: itga11 / 100489152
• XenbaseID: XB-GENE-483822
• Length: 1188
• Species: Xenopus tropicalis
• Alignment Length: 1361
• Identity: 267/1361 - (19%)
• Similarity: 461/1361 - (33%)
• Gaps: 488/1361 - (35%)

  Fly    34 FNLEQRLPIVKYGHPHSHFGYSVATHTIGEANGPNKTNCVLVGAPLDQNRQPNTTHSGALWRCPM 98
            ||::.:.|.:..|...:.|||:|..|.|.      ....::||||.|.|....|   |.:::|.:
 Frog    23 FNIDTKRPRIISGSKDAFFGYTVQQHQIA------GKKWLVVGAPFDVNGPQKT---GDIYKCSV 78

  Fly    99 T-QRFDDCEQVITDGRRNFDSEILSPPGNDEIKEDQWMGVTVRSNPLQANGSGGKVIVCAHRYMY 162
            | ...:||.: :..||....:.       .|.|::..:|:::.:||     .....:.|:..:.:
 Frog    79 TNDTSNDCTK-LGIGRVTLSNV-------SERKDNMRLGMSLVTNP-----KDNSFVACSPLWSH 130

  Fly   163 IVRENRYGQGLCYLLTNDLQFEEVHEPCKGR---------------------------------- 193
            ....:.|..|:|..:.::.:|..:..|...|
 Frog   131 ECGSSYYTTGMCSRVNSNFRFSRIVAPALQRCPTFMDIVIVLDGSNSIYPWVEVQSFLISILQKF 195

  Fly   194 ---PVQRQ-----------HEDY-----------------------------GLCQAGT------ 209
               |.|.|           ||.|                             |:.:|.|
 Frog   196 YIAPGQIQVGVLQYGETVVHEFYLNNYRSVTDVVEAAKRIEQRGGTETRTALGIEKAVTEAFQRG 260

  Fly   210 ----------------------------------------------------------------- 209
                                                                             
 Frog   261 GRKGAKKVMIVITDGESHDSPDLQRVIESSEKDNITRYAVAVLGYYNRRGINPEAFLNEIKYIAS 325

  Fly   210 ------------SAALLD-------------------------------------DDTMVLGSPG 225
                        .|||.|                                     :|.::||:.|
 Frog   326 DPDDKHFFNVTDEAALKDIVDALGERIFSLEGGTNKNETSFGLEMSQAGFSSHVVEDGILLGAVG 390

  Fly   226 PYTWRGSIWVTQVGGEYLQRDKTTYYSDHSDLNSPVDKYSYLGMSVTGGRFFGHMS-YAAGAPRS 289
            .|.|.|::......|:.:.| :.:|..:..|  ...:..:|||.:||....:..:. |.|||||.
 Frog   391 AYDWNGAVLKETSSGKVIPR-RESYLKEFPD--ELKNHGAYLGYTVTSVMTWQRVRIYVAGAPRF 452

  Fly   290 EGHGQVVIFDKSTDNPIPVHSILDGEQFGSSFGYELATADINGDHRPD-LIVAAPLYFTK-TEGG 352
            ...|:|::|.......:.:|..|.|.|.||.||.|:.:.|::||...| |:|.||:||.. .|.|
 Frog   453 NHTGKVIVFTMHGAENMTIHQALQGNQIGSYFGGEMDSVDVDGDGVTDILLVGAPMYFIDGWERG 517

  Fly   353 AVYVY--------QN--IQDTLPMKYTLKLTGPLESRFGLALANIGDLNKDNCEDLAVGAPYEGN 407
            .|.|:        .|  :||         |.....||||.::|.:.|||:|...|:.||||.|.|
 Frog   518 RVSVFVLRERQFIHNGFLQD---------LNSSQNSRFGSSIAAVPDLNQDLYNDVVVGAPLEDN 573

  Fly   408 --GVVYIYLGSSQGLNSKPAQKIQASELG-GTIPNGQPIRTFGISISGNTDLDDNSYPDVVIGAF 469
              |.:||:.|..:.:..|..|:|.|:||. |.:       .||.:|.|..|::::...|:.:|:.
 Frog   574 HKGAIYIFHGLRKNILKKYKQRISAAELAPGLV-------YFGCNIHGEMDMNEDGLVDLAVGSM 631

  Fly   470 NSSAAVILLARPIISIQTSVQ---------RKELHNMDPNTPGCLDDPASNLTCFT--FRACCSI 523
            .:  ||:|..|.::.|..::.         .|:.|. :.....|:    |...||:  |:|
 Frog   632 GN--AVLLWTRSVVKINATMHFEPPKINIFSKDCHR-NGREATCM----SAFICFSPMFKA---- 685

  Fly   524 EPYDEKNKELRLAYSVEAETFDHLKKFSRVFFFDRENKRTNVLSRVVRVHTNGRTECQAVTGYIK 588
            :.:..:|  :.:.|:|   :.|..:...|....|....:..|  :.:|. |:|..:||.:..::
 Frog   686 QQFQGQN--VAIKYNV---SIDERRYIPRAIIDDIGGDKHFV--KTIRA-TSGHNQCQQLNFHV- 741

  Fly   589 ANTRDIQTPVRFRLKYSLVEPPLADSALVRLNPILDQ---TQAHVDFEGTFQKDCGDDDLCESNL 650
            .:|.|...|:.|.|:|.|        |.....|:|::   |...|..  .|...|..|:.|..:|
 Frog   742 LDTADYVKPITFSLEYEL--------AFSDQGPVLEEDWPTSLKVSV--PFWNGCNQDERCVPDL 796

  Fly   651 IIRVEPNI-------------TESSGNEYTLILDET---------ELEVRINVSNLADSAYEAQL 693
            .:.|:.:|             |:|:..|:....|.:         .:.:.:.:.|..::||...|
 Frog   797 YLDVKHDIPTALEYCQRFLYRTQSACTEFISAFDNSVFIIQRSRRRVALEVVLENRGENAYSTAL 861

  Fly   694 FIAHQAGVSYVA--TKKPTN--ATCNS-----YNTTLVACSLGNPMLRDTT--------TFVTIR 741
            .|:|...:.:.:  ||:.::  ..|.|     :..|   |::..|..|...        .|...:
 Frog   862 NISHSQNLQFASLITKEDSDIKIECKSDDRFPHTKT---CNVSYPFFRAKAKVAFRLDFEFSKYQ 923

  Fly   742 FQPKGLEPSEKIMLFHIFANTTSKLVGPERPERDLRVN----------VVRRAKLNFRGWAIPEQ 796
            |.|        .:..|:.|.:.|:.....|.:.::.::          ..|.:.||
 Frog   924 FLP--------FLQVHLSAGSDSEEQESTRFDNEVLLDFHLKYESDLLFTRHSSLN--------- 971

  Fly   797 SFYSGSSVANSVANTAATDIEGHGPMGMDDVGSQVHHMFTIFNEGPSTAPKVQMVIHWPYSLYSD 861
                                               |:..|  :||.:..          |:....
 Frog   972 -----------------------------------HYEIT--SEGSADR----------YNAIGP 989

  Fly   862 P-QSGRPVQYLLYLEQVPTVEVSQGECHVAKEYVNPLNLASGSRENPAYLSAPAQMRMFPSQSRH 925
            | .|...:|.|.:                   :...:||.         ::.|...|   ..:|.
 Frog   990 PFNSSFKIQNLGF-------------------FPEEINLK---------ITVPVATR---GGNRL 1023

  Fly   926 SFNKSLIHSQRSYYSS--SHRDDHSDDTQSNRNRVRRSFLERVTRLERLMYDPESSNAANGKKQD 988
            .|..|||..|.:...:  .:..|:       |.:.....|.||.:|             |....|
 Frog  1024 LFLHSLISDQENAVCNIWGNSTDY-------RRKPTEEDLSRVPQL-------------NHSNSD 1068

  Fly   989 IVELDCNKGATNCVRIECDILNMPALSEAQVVVKARLWNSTLVSEYPRVERVRIFSTATAQIPES 1053
            ::.:||             :|.:.:..||..::...||:.:..:...|...|.:|:....:....
 Frog  1069 VISIDC-------------VLILASNQEASFILHGDLWSRSFRAMNFRSVNVVVFAALQRKFQSP 1120

  Fly  1054 YGVEVMDHNNIEVETRAYPELRNQQRDTSIPWLIIILGIVGGLLLLALVTYVLWKVGFFKR 1114
            :....      |..||......::|.:..:|..:||...:||||||||:...|||:|||||
 Frog  1121 FIFRE------EEPTRQITFAISKQEEWEVPIWVIITSTLGGLLLLALLVLALWKLGFFKR 1175

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mew	NP_001285196.1	Int_alpha	48..111	CDD:214549	18/63 (29%)
		Int_alpha	317..368	CDD:214549	22/62 (35%)
		Int_alpha	378..428	CDD:214549	22/51 (43%)
		Int_alpha	446..491	CDD:214549	12/53 (23%)
		Integrin_alpha2	479..1006	CDD:285619	98/592 (17%)
itga11	XP_017947982.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910