Protein Alignment REG and PSME2

DIOPT Version :9

• Sequence 1: NP_001259502.1
• Gene: REG / 32274
• FlyBaseID: FBgn0029133
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_002809.2
• Gene: PSME2 / 5721
• HGNCID: 9569
• Length: 239
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 78/238 - (32%)
• Similarity: 127/238 - (53%)
• Gaps: 14/238 - (5%)

  Fly     8 KVQEYKDSLILKAELLITKGFPENIVRLNELLATPIFNERNFEEVHQDLNIPVLPPLLVKNELED 72
            :|:.::.:|..:||..:.:..|:.|:.||:||.....|..:...:...|:||:..|....:|:|
Human    16 QVEVFRQNLFQEAEEFLYRFLPQKIIYLNQLLQEDSLNVADLTSLRAPLDIPIPDPPPKDDEME- 79

  Fly    73 RDSLPTKRQRVDVIVSGQPVMGLPAGTVPCNKPLCEMIKVVKPIIRKLVEDSNLLKMWISFMIPK 137
                ..|:::.:|         ...|.:|.|:.:..::.:|||.:..|.|...|:..||..:|||
Human    80 ----TDKQEKKEV---------HKCGFLPGNEKVLSLLALVKPEVWTLKEKCILVITWIQHLIPK 131

  Fly   138 IEDGNNFGVSIQEDTLAEIQTVESEAAAFFDQISRYFLSRAKVVSKVAKYPHIDDYRRAVVELDE 202
            |||||:|||:|||..|..:..|:::..||...||:||..|...|:|.:|..|:.|||..|.|.||
Human   132 IEDGNDFGVAIQEKVLERVNAVKTKVEAFQTTISKYFSERGDAVAKASKETHVMDYRALVHERDE 196

  Fly   203 KEYLSLWLVVCEVRNRYSSLHDIVIKNLEKLKKPRSSNTESLY 245
            ..|..|..:|.::|..|:.|:.|:..||||:..|:.....|:|
Human   197 AAYGELRAMVLDLRAFYAELYHIISSNLEKIVNPKGEEKPSMY 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
REG	NP_001259502.1	PA28_alpha	5..60	CDD:280421	13/51 (25%)
		PA28_beta	102..243	CDD:280422	55/140 (39%)
PSME2	NP_002809.2	PA28_alpha	13..65	CDD:280421	11/48 (23%)
		PA28_beta	96..237	CDD:280422	55/140 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158102
Domainoid	1	1.000	45	1.000	Domainoid score	I12213
eggNOG	1	0.900	-	-		E1_KOG4470
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1251022at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10660
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.810