DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment REG and psme1

DIOPT Version :9

Sequence 1:	NP_001259502.1	Gene:	REG / 32274	FlyBaseID:	FBgn0029133	Length:	245	Species:	Drosophila melanogaster
Sequence 2:	NP_571450.1	Gene:	psme1 / 30648	ZFINID:	ZDB-GENE-991110-17	Length:	248	Species:	Danio rerio

Alignment Length:	235	Identity:	83/235 - (35%)
Similarity:	136/235 - (57%)	Gaps:	14/235 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 KVQEYKDSLILKAELLITKGFPENIVRLNELLATPIFNERNFEEVHQDLNIPVLPPLLVKNEL-- 70
            :|..:...:..:||.||:|.|||.|..::.:|.... :.::...:...|:||:..|  ||.||
Zfish    13 QVDGFSQKITKEAEQLISKIFPEKIAEMDNVLQGSC-SLKDLSVIKAPLDIPIPDP--VKEELKR 74

  Fly    71 ---EDRDSLPTKRQRVDVIVSGQPVMGLPAGTVPCNKPLCEMIKVVKPIIRKLVEDSNLLKMWIS 132
               |::::...|:.:.|      ...|.|.|.:.||:.:.::||.:||.|:.|.|..|.:.|||.
Zfish    75 KKKEEKEAKEGKKDKED------EDAGPPCGPIACNETVEKLIKQIKPEIQTLKECLNTVSMWIQ 133

  Fly   133 FMIPKIEDGNNFGVSIQEDTLAEIQTVESEAAAFFDQISRYFLSRAKVVSKVAKYPHIDDYRRAV 197
            ..:|:|||||||||::||.....:....::...|..|||:|:..|...|:|.:|.||:.|:|:.|
Zfish   134 LQVPRIEDGNNFGVAVQEKVFELMTNTRTKIEGFQTQISKYYSERGDAVAKASKQPHVGDFRQLV 198

  Fly   198 VELDEKEYLSLWLVVCEVRNRYSSLHDIVIKNLEKLKKPR 237
            .|||:.:|..|.::|.|:||.|:.|:|::.||.:|:||||
Zfish   199 HELDQHQYCELRIIVLEIRNTYAMLYDVITKNFDKIKKPR 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
REG	NP_001259502.1	PA28_alpha	5..60	CDD:280421	13/51 (25%)
REG	NP_001259502.1	PA28_beta	102..243	CDD:280422	58/136 (43%)
psme1	NP_571450.1	PA28_alpha	10..66	CDD:280421	14/53 (26%)
psme1	NP_571450.1	PA28_beta	103..240	CDD:280422	58/136 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593977
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4470
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1251022at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10660
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	6	5.810