Protein Alignment sno and Sbno1

DIOPT Version :10

• Sequence 1: NP_001096967.1
• Gene: sno / 32273
• FlyBaseID: FBgn0265630
• Length: 1653
• Species: Drosophila melanogaster
• Sequence 2: XP_038945368.1
• Gene: Sbno1 / 304470
• RGDID: 1310005
• Length: 1394
• Species: Rattus norvegicus
• Alignment Length: 1525
• Identity: 775/1525 - (50%)
• Similarity: 987/1525 - (64%)
• Gaps: 208/1525 - (13%)

  Fly   146 ATPTVGGVALGGKLTVIPIAGRNVALDNNLSNMPKKLNNMVTAMGSPA---ARSSGNAGTT---- 203
            ||||...|...     :|::...:.|:...:...|:...|   |.:||   .|....:.||
  Rat    34 ATPTPPSVQQS-----VPLSALELGLETEAAIPVKQEPEM---MSTPALLNVRQQPPSTTTFVLN 90

  Fly   204 GSSQGGAIGSTSSYLNS--LTTN-ELMNLAAYVAAKGSNAPPPPPPSTAANSVRHSPTGGIPNPG 265
            ..:|...:|||.....:  .||| :.:.|..::....:..     ||.:|.:||::    ||
  Rat    91 QINQLPTLGSTIVMTKTPPATTNRQTITLTKFIQTTANTR-----PSVSAPAVRNA----IP--- 143

  Fly   266 GNFFGGSAAASTSASAANFNMAASLLAQMSYAGGASQIRALKVAGNIGGVGNNQKPPPIATTPGS 330
                        .|.|.:......||...|    .:::..||...||.      :|...|.|..|
  Rat   144 ------------PAPAKDQVQLKDLLKNNS----LNELMKLKPPANIA------QPVATAATDVS 186

  Fly   331 GGPAGGAPGSGVKGNNSMMEAVQKLIAMNPEYLTSGIPNTVFQMFMQSMQRPQATPSPNQPMNPG 395
            .|        .||..:|..|                    |.::::..|:....:|:...|
  Rat   187 NG--------AVKKESSNKE--------------------VARVWINDMKMRSFSPTMKVP---- 219

  Fly   396 AMVTSAAAAAAHASAVAYVQQEEDEVDYEEMGVAETYADYWPAKLKLGKKHPDAVVETASLSSVE 460
                           |...:.|.:|.|.||||.|||||:|.|.|||:|.:||||||||:|||||.
  Rat   220 ---------------VVREEDEPEEEDEEEMGHAETYAEYMPIKLKIGLRHPDAVVETSSLSSVT 269

  Fly   461 PCDVYYKLSLPLETINSGHLSALQLESITYASQAHDHLLPDGSRAGFLIGDGAGVGKGRTIAGII 525
            |.||:||.|:..|||::|.|||||||::|||:|.|:..||:|.||||||||||||||||||||||
  Rat   270 PPDVWYKTSISEETIDNGWLSALQLEAVTYAAQQHETFLPNGDRAGFLIGDGAGVGKGRTIAGII 334

  Fly   526 YENYLKGRKKALWISVSNDLKYDAERDLSDIGATRIEVHALNKFKYAKISSDVNNNCKRGVIFST 590
            |||||..||:|||.||||||||||||||.||||..|.||:||||||.||||..|.:.|:||||:|
  Rat   335 YENYLLSRKRALWFSVSNDLKYDAERDLRDIGAKNILVHSLNKFKYGKISSKHNGSVKKGVIFAT 399

  Fly   591 YSALIGESNNKTGKYRSRFRQLLQWCGEDFEGLIIFDECHKAKNLCPVGSGKPTKTGQTVLELQQ 655
            ||:|||||.: .|||::|.:|||.|||:||:|:|:|||||||||||||||.||||||..|||||.
  Rat   400 YSSLIGESQS-GGKYKTRLKQLLHWCGDDFDGVIVFDECHKAKNLCPVGSSKPTKTGLAVLELQN 463

  Fly   656 KLPKARVVYASATGASEPKNMAYMVRLGLWGQGTAFGNFNDFITAVERRGVGAMEIVAMDMKLRG 720
            ||||||||||||||||||:|||||.|||:||:||.|..|:|||.|||||||||||||||||||||
  Rat   464 KLPKARVVYASATGASEPRNMAYMNRLGIWGEGTPFREFSDFIQAVERRGVGAMEIVAMDMKLRG 528

  Fly   721 MYIARQLSFKGVSFKIEEVPLSKEFRKIYDQSVELWVEAMQKFTEAAELIDAESRMKKTMWGQFW 785
            |||||||||.||:||||||.||:.:.|:|:::|:|||.|.::|.:||:|||||.||||:||||||
  Rat   529 MYIARQLSFTGVTFKIEEVLLSQSYVKMYNKAVKLWVIARERFQQAADLIDAEQRMKKSMWGQFW 593

  Fly   786 SSHQRFFKYLCIAAKVNHAVLVARESIKYGKCVVIGLQSTGEARTLDQLERDDGELTDFVSTAKG 850
            |:|||||||||||:||...|.:|||.||.|||||||||||||||||:.||...|||.||||||||
  Rat   594 SAHQRFFKYLCIASKVKRVVQLAREEIKNGKCVVIGLQSTGEARTLEALEEGGGELNDFVSTAKG 658

  Fly   851 VFQSFVERHFPAPDRNRINRILGLYDETPSLSSVADSTSSLSNNSNITTAAGKRKGSNNNDNRST 915
            |.||.:|:|||||||.::..:||:           |.|:. ||||:          ..::..:..
  Rat   659 VLQSLIEKHFPAPDRKKLYSLLGI-----------DLTAP-SNNSS----------PRDSPCKEN 701

  Fly   916 KIKKKKRSGSWECSDSEDENTDMKRNRKRDGGNSNSDSDEANSDDDLKSDIDDEDEDHDVDSDQR 980
            ||||:|         .|:...:.|:.|| .||.:.|.||::.|:.|:.   |:|:.|::   ..:
  Rat   702 KIKKRK---------GEEITREAKKARK-IGGLTGSSSDDSGSESDVS---DNEESDYE---SSK 750

  Fly   981 SVASDASSDFNPF--FSGSDSDIDPWVNARSKKSKKAQKKSKKKVKKEKTKKEITTS--SATDPS 1041
            :::|....|||||  .|..|::.|||:..:..|..| .||.||.:..:..:..:..|  .:..||
  Rat   751 NMSSGDDDDFNPFRDESSEDNEDDPWLIRKDHKKSK-DKKKKKSIDPDSIQSALLASGLGSKRPS 814

  Fly  1042 GSTA---MSATVVAALNAVKNRKSQLSTQDKIQDLLQKKQELKGTVTPVGVNGVKLNYGPPPKDA 1103
            .|:|   ..|:..|..|:..|..|.|.|.                                 :||
  Rat   815 FSSAPVISPASNSAPANSNSNSNSSLITS---------------------------------QDA 846

  Fly  1104 IERACTMKEELLRKIERLGARLPPNTLDQLIDELGGPDNVAEMTGRRGRVVQTDDGSIQYESRTE 1168
            :|||..||::||.|:|:|...|||||||:||||||||:||||||||:||||..|||||.||||:|
  Rat   847 VERAQQMKKDLLDKLEKLAEDLPPNTLDELIDELGGPENVAEMTGRKGRVVSNDDGSISYESRSE 911

  Fly  1169 SDVPLETLNITEKQRFMDGEKDVAIISEAASSGISLQSDRRVFNQRRRVHITLELPWSADRAIQQ 1233
            .|||:|.||||||||||||:|::||||||||||||||:|||..|||||||:||||||||||||||
  Rat   912 LDVPVEILNITEKQRFMDGDKNIAIISEAASSGISLQADRRAKNQRRRVHMTLELPWSADRAIQQ 976

  Fly  1234 FGRTHRSNQVNAPEYIFLISDLAGERRFASTVAKRLESLGALTHGDRRATETRDLSQFNIDNKYG 1298
            ||||||||||.||||:||||:||||:||||.||||||||||||||||||||:||||:||.|||||
  Rat   977 FGRTHRSNQVTAPEYVFLISELAGEQRFASIVAKRLESLGALTHGDRRATESRDLSRFNFDNKYG 1041

  Fly  1299 RQALETVMRTIMGYESPLVPPPTDYSGEFFKDIAGALVGVGIIVNSESHPGVLSLDKDYNNISKF 1363
            |.|||.||::|:..:||:|.||.||.||||||:...|:|||:| |.|...|:|:||||||||.||
  Rat  1042 RNALEIVMKSIVNLDSPMVSPPPDYPGEFFKDVRQGLIGVGLI-NVEDRSGILTLDKDYNNIGKF 1105

  Fly  1364 LNRILGCPVDLQNRLFKYFTDTMTAIIQQAKRGGRFDLGILDLGAAGENVTRVRLIRFVRKHATG 1428
            ||||||..|..||.||:||.||:||::|.||:.||:|:||||||:..|.|.:..:.:|:....:.
  Rat  1106 LNRILGMEVHQQNALFQYFADTLTAVVQNAKKNGRYDMGILDLGSGDEKVRKSDVKKFLTPGYST 1170

  Fly  1429 VAPTEMHTVRVERGMIWQEAIDKYADLFNENEGFYLSHQ--LRNQKRTAIMVVILESRNSSSTSS 1491
            ....|::|:.|||||.|.||...:|:|...::|||||.|  :||.|:|||:|
  Rat  1171 SGHVELYTISVERGMSWDEATKIWAELTGPDDGFYLSLQVRIRNNKKTAILV------------- 1222

  Fly  1492 TTDLDSGSKKKKTHSKKEIMCQIYRPNTGLQVRHESLFELEKKYRKVASEEAEPHWTEQYDASVN 1556
                      |:.:.||::.. |||||||.|::.|...:|:|||:||.|::|..||.:||::|.:
  Rat  1223 ----------KEVNPKKKLFL-IYRPNTGKQLKLEIYADLKKKYKKVVSDDALVHWLDQYNSSAD 1276

  Fly  1557 TCSHAYWNGNCRNVSLGNDCEVGLRQRLYHVLAGSVLSVWGRVEHILNTRS--NSKMQVIRMKTT 1619
            ||:||||.|||:..|||..||:|||.|.|:||.|||||||.:||.:|.:.|  |.|||::|::|.
  Rat  1277 TCTHAYWRGNCKKASLGLVCEIGLRCRTYYVLCGSVLSVWTKVEGVLASVSGTNVKMQIVRLRTE 1341

  Fly  1620 EGEKIVGTLIPKSCFEPLVADLRSDSEKQE 1649
            :|::|||.:||.:|..|||..|.:..:.|:
  Rat  1342 DGQRIVGLIIPANCVSPLVNLLSTSDQSQQ 1371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sno	NP_001096967.1	AAA_34	448..750	CDD:464010	229/301 (76%)
		Helicase_C_4	1128..1405	CDD:464009	210/276 (76%)
Sbno1	XP_038945368.1	AAA_34	257..559	CDD:464010	230/302 (76%)
		Helicase_C_4	871..1147	CDD:464009	210/276 (76%)