Protein Alignment sno and sbno1

DIOPT Version :10

• Sequence 1: NP_001096967.1
• Gene: sno / 32273
• FlyBaseID: FBgn0265630
• Length: 1653
• Species: Drosophila melanogaster
• Sequence 2: NP_001186845.2
• Gene: sbno1 / 100005813
• ZFINID: ZDB-GENE-080522-2
• Length: 1386
• Species: Danio rerio
• Alignment Length: 1471
• Identity: 761/1471 - (51%)
• Similarity: 963/1471 - (65%)
• Gaps: 220/1471 - (14%)

  Fly   213 STSSYLNSLTTNELMNLAAYVAAKGSNAPPPPPPSTAANS--------VRHSPTGGIPNPGGNFF 269
            :|:..||.|  |:|.:|...|.:|         |||.:::        |.||
Zfish    79 TTTFVLNQL--NQLPSLGTIVVSK---------PSTGSSTRQTITVTKVLHS------------- 119

  Fly   270 GGSAAASTSASAANFNMAASLLAQMSYAGGASQIR--------ALKVAGNIGGVGNNQKP----P 322
              |:.|..|:::.:...||        .....|||        :|| :.::|.:...:.|    |
Zfish   120 --SSPAQRSSASPSVCTAA--------PANTEQIRLKDLLRSSSLK-SSSLGELMKLKPPADIAP 173

  Fly   323 PIATTPGSGGPAGGAPGSGVKGNNSMMEAVQK----LIAMNPEYLTSGIPNTVFQMFMQSMQRPQ 383
            |:||..|:           .:.||.:.:.|..    .|.:|.:            |.|:|.
Zfish   174 PVATATGT-----------TEVNNGLKKEVSSKDVARIWINDD------------MKMRSF---- 211

  Fly   384 ATPSPNQPMN--PGAMVTSAAAAAAHASAVAYVQQEEDEVDYEEMGVAETYADYWPAKLKLGKKH 446
                  .|:|  ||..                .::|.:|.:.||:|.|||||:|.|.||::|.:|
Zfish   212 ------SPVNKLPGMK----------------EEEEPEEEEEEELGHAETYAEYMPMKLRIGLRH 254

  Fly   447 PDAVVETASLSSVEPCDVYYKLSLPLETINSGHLSALQLESITYASQAHDHLLPDGSRAGFLIGD 511
            ||.||||:|||||.|.||:|:||:|.|||:.|.|||||||::|||:|.|:..||:|.||.:||||
Zfish   255 PDPVVETSSLSSVNPPDVWYRLSIPEETIDRGWLSALQLEAVTYAAQQHETFLPNGDRAAYLIGD 319

  Fly   512 GAGVGKGRTIAGIIYENYLKGRKKALWISVSNDLKYDAERDLSDIGATRIEVHALNKFKYAKISS 576
            |||||||||||||||||||.|||::||.||||||||||||||.||||..|:||:||||||.||||
Zfish   320 GAGVGKGRTIAGIIYENYLLGRKRSLWFSVSNDLKYDAERDLRDIGAKNIQVHSLNKFKYGKISS 384

  Fly   577 DVNNNCKRGVIFSTYSALIGESNNKTGKYRSRFRQLLQWCGEDFEGLIIFDECHKAKNLCPVGSG 641
            ..|.:.|:||||:|||:|||||.: .|||::||:|||.|||:||:|:|:|||||||||:||:||.
Zfish   385 KHNGSVKKGVIFATYSSLIGESQS-GGKYKTRFKQLLHWCGDDFDGVIVFDECHKAKNVCPIGSS 448

  Fly   642 KPTKTGQTVLELQQKLPKARVVYASATGASEPKNMAYMVRLGLWGQGTAFGNFNDFITAVERRGV 706
            ||||||..|||||.||||||||||||||||||:|||||.|||:||:||.|..|.:||.|||||||
Zfish   449 KPTKTGLAVLELQNKLPKARVVYASATGASEPRNMAYMNRLGIWGEGTPFREFANFIQAVERRGV 513

  Fly   707 GAMEIVAMDMKLRGMYIARQLSFKGVSFKIEEVPLSKEFRKIYDQSVELWVEAMQKFTEAAELID 771
            |||||||||||||||||||||||.||:||||||||:.::.|:|:::|.|||.|.:||.:||:|:|
Zfish   514 GAMEIVAMDMKLRGMYIARQLSFTGVTFKIEEVPLTLDYIKMYNKAVRLWVSAREKFQQAAQLMD 578

  Fly   772 AESRMKKTMWGQFWSSHQRFFKYLCIAAKVNHAVLVARESIKYGKCVVIGLQSTGEARTLDQLER 836
            ||.||||:|||||||:|||||||||||:||...|.:|||.:|.|||||||||||||||||:.||.
Zfish   579 AEQRMKKSMWGQFWSAHQRFFKYLCIASKVRRVVQLAREDVKNGKCVVIGLQSTGEARTLEALEE 643

  Fly   837 DDGELTDFVSTAKGVFQSFVERHFPAPDRNRINRILGLYDETPSLSSVADSTSSLSNNSNITTAA 901
            ..|||.|||||||||.||.||:|||||||.::..:||:     .||  |..|.|.:.|
Zfish   644 GGGELNDFVSTAKGVLQSLVEKHFPAPDRQKLFSLLGI-----DLS--AKKTPSPAEN------- 694

  Fly   902 GKRKGSNNNDNRSTKIKKKKRSGSWECSDSEDENTDMKRNRKRDGGNSNSDSDEANSDDDLKSDI 966
                        .|:.|.|||.|       .:....:|:.|| .||.|.|.||:::|
Zfish   695 ------------KTEQKGKKRKG-------PESKKHVKKARK-SGGLSGSSSDDSSS-------- 731

  Fly   967 DDEDEDHDVDSDQ--RSVASDASSDFNPF--FSGSDSDIDPW-VNARSKKSK-KAQKKSKKKVKK 1025
              ||.|.|.:||.  :|::|....|||||  .|..|.:.||| :...||||| |..||.||.:..
Zfish   732 --EDSDRDAESDDSFKSISSGDEDDFNPFKDDSSEDEEDDPWLIRKDSKKSKDKRNKKKKKSIDP 794

  Fly  1026 EKTKKEITTSSATDPSGSTAMSATVVAALNAVKNRKSQLSTQDKIQDLLQKKQELKGTVTPVGVN 1090
            :..:..:..|..    |:|..:.|.     .:|.....|:       :.:...|....||
Zfish   795 DSIQSALLASGL----GTTRPTFTA-----PIKPANPTLA-------VAKSDPEESSCVT----- 838

  Fly  1091 GVKLNYGPPPKDAIERACTMKEELLRKIERLGARLPPNTLDQLIDELGGPDNVAEMTGRRGRVVQ 1155
                     .:||:|.|..||.:||.|:|.|...|||||||||||||||||||||||||:||||.
Zfish   839 ---------SQDAVEDAQRMKRDLLEKLELLAEDLPPNTLDQLIDELGGPDNVAEMTGRKGRVVS 894

  Fly  1156 TDDGSIQYESRTESDVPLETLNITEKQRFMDGEKDVAIISEAASSGISLQSDRRVFNQRRRVHIT 1220
            .|||||.||||:|.|||:|.||:|||||||||:|::||||||||||||||:||||.|||||||:|
Zfish   895 NDDGSISYESRSELDVPVEILNLTEKQRFMDGDKNIAIISEAASSGISLQADRRVKNQRRRVHMT 959

  Fly  1221 LELPWSADRAIQQFGRTHRSNQVNAPEYIFLISDLAGERRFASTVAKRLESLGALTHGDRRATET 1285
            |||||||||||||||||||||||.||||:||||:||||:||||.|||||||||||||||||||||
Zfish   960 LELPWSADRAIQQFGRTHRSNQVTAPEYVFLISELAGEQRFASIVAKRLESLGALTHGDRRATET 1024

  Fly  1286 RDLSQFNIDNKYGRQALETVMRTIMGYESPLVPPPTDYSGEFFKDIAGALVGVGIIVNSESHPGV 1350
            ||||:||.||||||.|||.||::|:..:||||.||.|:.|:|||:|...|:|||:| |.|...||
Zfish  1025 RDLSRFNFDNKYGRNALEIVMKSIVSLDSPLVSPPADFDGDFFKEIRNGLIGVGLI-NVEDRSGV 1088

  Fly  1351 LSLDKDYNNISKFLNRILGCPVDLQNRLFKYFTDTMTAIIQQAKRGGRFDLGILDLGAAGENVTR 1415
            ||||||||||.||||||||..|..||.||:||:||::|:||.||:.||:|:||||||:..|.|.:
Zfish  1089 LSLDKDYNNIGKFLNRILGMEVQQQNALFQYFSDTLSAVIQNAKKSGRYDMGILDLGSGDEKVKK 1153

  Fly  1416 VRLIRFVRKHATGVAPTEMHTVRVERGMIWQEAIDKYADLFNENEGFYLSHQLRNQKRTAIMVVI 1480
            |.:.:|:....:.....|::||.|||||.|:||...:||....::|||:  |:||.|:.||:|
Zfish  1154 VDVKKFLTPGYSTSGHVELYTVSVERGMSWEEATHVWADQNGPDDGFYV--QVRNNKKIAILV-- 1214

  Fly  1481 LESRNSSSTSSTTDLDSGSKKKKTHSKKEIMCQIYRPNTGLQVRHESLFELEKKYRKVASEEAEP 1545
                                 |:.:.:|.:. .:||||.|.||:.|:..:::|:.:||.|::|:.
Zfish  1215 ---------------------KEVNPRKRLF-MVYRPNIGKQVKLETYTDIKKRSKKVLSDDAKQ 1257

  Fly  1546 HWTEQYDASVNTCSHAYWNGNCRNVSLGNDCEVGLRQRLYHVLAGSVLSVWGRVEHILNTRS--N 1608
            ||.:||..|.:.||||||.|||:..|:|..||:|||.|.|.||.|||||||.:||.:|.:.|  |
Zfish  1258 HWMDQYSCSADVCSHAYWRGNCKKASVGLQCEIGLRCRTYFVLCGSVLSVWTKVEGVLASVSGAN 1322

  Fly  1609 SKMQVIRMKTTEGEKIVGTLIPKSCFEPLVADLRSDSEKQE 1649
            .|||::|::|.:|::|||.:||::|..|||..|.|..:.|:
Zfish  1323 VKMQIVRLRTEDGQRIVGLIIPQNCVSPLVNILSSSDQSQQ 1363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sno	NP_001096967.1	AAA_34	448..750	CDD:464010	225/301 (75%)
		Helicase_C_4	1128..1405	CDD:464009	214/276 (78%)
sbno1	NP_001186845.2	AAA_34	256..558	CDD:464010	226/302 (75%)
		Helicase_C_4	867..1143	CDD:464009	214/276 (78%)