DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12096 and SPCC18.17c

DIOPT Version :9

Sequence 1:	NP_001285190.1	Gene:	CG12096 / 32269	FlyBaseID:	FBgn0030457	Length:	506	Species:	Drosophila melanogaster
Sequence 2:	NP_588396.1	Gene:	SPCC18.17c / 2539160	PomBaseID:	SPCC18.17c	Length:	488	Species:	Schizosaccharomyces pombe

Alignment Length:	535	Identity:	109/535 - (20%)
Similarity:	192/535 - (35%)	Gaps:	114/535 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LKALESKPQRL-----DALTAMNSAIAKEAALPRQIIERLLTTDQLYDCANPAADSHVPKDQAVD 71
            ||.|.|.|..:     ||:.|.     :|:..|......|...|.:..|..            :.
pombe    21 LKDLPSNPSVIVREIPDAIDAF-----RESITPATRPSCLGLLDTILSCFE------------LP 68

  Fly    72 VTLELLCHCLDQL--AMDTADEQ---LSSLLRRGLTHSNPALRAQVLASLFKKLLRQLTVGQVLT 131
            :..|.:...|.:|  .|..||.:   :.|.|..||.|.:..:....|..:.:....:..:|:
pombe    69 IPTEPIMKALGKLLEPMSWADLKKFGIESYLVTGLEHPSTDVEIFCLHLIRRANWEKKEIGE--- 130

  Fly   132 LPNNELIFLILDELKQPDTQSTSLAINILSIVLPQRISNADVQAKLVQLLKQ---------NEIV 187
             |..|.|...::        |.|:|::..:.||  ....||.......::|:         |..:
pombe   131 -PLFEAIMACIN--------SRSIAVSEEATVL--LFDMADFPYYFNLIIKRFTFVDYEIMNSTL 184

  Fly   188 RCRAYELAVVLAKKS----ATLLSDVTFILDAALSELDNDDVLLQASVMELLVPLAEQNHGLSYM 248
            |.|...|...|:.||    ..|:.|...:::.     ||.|:|||.:.:::|..:.|......|:
pombe   185 RVRWLTLFAKLSTKSPEYLEELIKDDKLVING-----DNKDILLQINFVDVLGIMLEAPFTYEYI 244

  Fly   249 --ERRRVLDIISYRVQRVEEHPLDALLVPSIMKFFGKISVYQPLKIIGGYPHMLACLFMQLQSED 311
              |:.:.||.|:...:...:...|.:    .:||..::....|..|               .|.|
pombe   245 SSEKTKYLDTIAQDYKGSADSYTDHI----GLKFLPRLCELHPDAI---------------NSLD 290

  Fly   312 E-----SILPTAMDTLANLATTPQGKILLNMHFSGAMEKSFKKYG---SHTKKLSAHIKKRLLNS 368
            |     ..:...|.|....:....|..|.|...:.|:   .||||   ...:.:...:.:|.|..
pombe   291 EKHQLFDAVRERMKTNDATSILLYGVFLSNTVVTQAL---IKKYGIEDEANRYVPRWLTRRFLMD 352

  Fly   369 LDVIYDFKTPPATEIINIGKN-WYECFAGGAHANIIMDLINT---PFPDLQMAALSFLKTICKYN 429
            ...:..|    |..::....| |.:.:. ....|.:..|:||   |.|..:..|...|..|.:.:
pombe   353 EPGMSSF----AHALLQPDHNLWMQLWR-ILPPNTLSTLVNTASSPIPRSRQLAYQCLLHIAQNS 412

  Fly   430 WGIVALKNTGGAVEFLLSRQKDLHRDIKYMKWQIMEILSASAEFSPTETIRFTAY-------VNE 487
              .:.:.:.|.|:..||..:.|  .:...:::|:::.:..|....|  .:.|..|       :.:
pombe   413 --PIQIASEGFAIRHLLEAEGD--HETCLLRFQVLKTMMESPHGGP--KLPFGRYREDILKRLQQ 471

  Fly   488 GPYHVQAD-LDVATE 501
            ||....|. |.||.|
pombe   472 GPIVSGASTLKVAAE 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12096	NP_001285190.1	Proteasom_PSMB	4..502	CDD:287479	109/535 (20%)
SPCC18.17c	NP_588396.1	Proteasom_PSMB	99..>281	CDD:287479	42/204 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4413
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_104314
Panther	1	1.100	-	-	LDO	PTHR13554
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.900