DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Bap60 and Smarcd3

DIOPT Version :9

Sequence 1:	NP_511143.2	Gene:	Bap60 / 32268	FlyBaseID:	FBgn0025463	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	XP_006535860.1	Gene:	Smarcd3 / 66993	MGIID:	1914243	Length:	535	Species:	Mus musculus

Alignment Length:	478	Identity:	296/478 - (61%)
Similarity:	365/478 - (76%)	Gaps:	37/478 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 GMRPYPPPGASFPPRGFPLHPNTTQPVPGTANVAGVPGV-PGVPGVPGPSLLQRAAQQPGFQSSL 87
            |:||..|.||..|.:|.|:.|      ||:..: |.|.| ||:.........:|||..|| ||..
Mouse    25 GVRPGMPSGARMPHQGAPMGP------PGSPYM-GSPAVRPGLAPAGMEPARKRAAPPPG-QSQA 81

  Fly    88 RGTGAGGGGVGSGGGSKRSNESRSLGGGGSKSDFATAKKKKKLAEKILPQKVRDLVPESQAYMDL 152
            :|.|.   .|.:.....||                  .|::|:|:|||||::|:|||||||||||
Mouse    82 QGQGQ---PVPTAPARSRS------------------AKRRKMADKILPQRIRELVPESQAYMDL 125

  Fly   153 LTFERKLDATIMRKRLDIQEALKRPMKQKRKLRIFISNTFYPSKEPTNDGEEGAVASWELRVEGR 217
            |.||||||.||||||:|||||||||||||||||::|||||.|:| |..:..:|::|||||||||:
Mouse   126 LAFERKLDQTIMRKRVDIQEALKRPMKQKRKLRLYISNTFNPAK-PDAEDSDGSIASWELRVEGK 189

  Fly   218 LLEDGKGDPNTKIKRKFSSFFKSLVIELDKELYGPDNHLVEWHRTHTTQETDGFQVKRPGDRNVR 282
            ||:|     .:|.|||||||||||||||||:||||||||||||||.|||||||||||||||.:||
Mouse   190 LLDD-----PSKQKRKFSSFFKSLVIELDKDLYGPDNHLVEWHRTPTTQETDGFQVKRPGDLSVR 249

  Fly   283 CTILLLLDYQPLQFKLDPRLARLLGVHTQTRPVIISALWQYIKTHKLQDAHEREYINCDKYLEQI 347
            ||:||:|||||.|||||||||||||:|||:|..|:.|||||:||::|||:|::||||.|||.:||
Mouse   250 CTLLLMLDYQPPQFKLDPRLARLLGLHTQSRSAIVQALWQYVKTNRLQDSHDKEYINGDKYFQQI 314

  Fly   348 FSCQRMKFAEIPQRLNPLLHPPDPIVINHFIE-SGAENKQTACYDIDVEVDDTLKNQMNSFLMST 411
            |.|.|:||:||||||..||.|||||||||.|. ..::.|:||||||||||::.||.||:|||:||
Mouse   315 FDCPRLKFSEIPQRLTALLLPPDPIVINHVISVDPSDQKKTACYDIDVEVEEPLKGQMSSFLLST 379

  Fly   412 ASQQEIQGLDTKIHETVDTINQMKTNREFFLSFAKDPQMFIHRWIISETRDLKLMTDVAGNPEEE 476
            |:||||..||:|||||:::|||:|..|:|.|||::||:.::...:.|::||||:|||||||||||
Mouse   380 ANQQEISALDSKIHETIESINQLKIQRDFMLSFSRDPKGYVQDLLRSQSRDLKVMTDVAGNPEEE 444

  Fly   477 RRAEFYYQPWTHEAVSRYFFTKV 499
            ||||||:|||:.|||||||:.||
Mouse   445 RRAEFYHQPWSQEAVSRYFYCKV 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bap60	NP_511143.2	SWIB_BAF60A	295..371	CDD:349493	53/75 (71%)
Smarcd3	XP_006535860.1	Rsc6	179..376	CDD:227818	147/201 (73%)
Smarcd3	XP_006535860.1	SWIB_BAF60C	265..338	CDD:349495	50/72 (69%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	286	1.000	Domainoid score	I1593
eggNOG	1	0.900	-	-		E1_COG5531
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	629	1.000	Inparanoid score	I852
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55104
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000716
OrthoInspector	1	1.000	-	-		otm42871
orthoMCL	1	0.900	-	-		OOG6_100964
Panther	1	1.100	-	-	O	PTHR13844
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1401
SonicParanoid	1	1.000	-	-		X681
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.860