Protein Alignment Bap60 and SMARCD2

DIOPT Version :10

• Sequence 1: NP_511143.2
• Gene: Bap60 / 32268
• FlyBaseID: FBgn0025463
• Length: 515
• Species: Drosophila melanogaster
• Sequence 2: NP_001091896.1
• Gene: SMARCD2 / 6603
• HGNCID: 11107
• Length: 531
• Species: Homo sapiens
• Alignment Length: 557
• Identity: 305/557 - (54%)
• Similarity: 366/557 - (65%)
• Gaps: 91/557 - (16%)

  Fly     6 APGQAPVQSRY-QPPPPA-PGMRPYP-------------PPGASFPPRGFP-----------LHP 44
            :||...|.:.. .||||| |||.|.|             |..|:|.|.| |           :.|
Human    15 SPGGGAVAAALGAPPPPAGPGMLPGPALRGPGPAGGVGGPGAAAFRPMG-PAGPAAQYQRPGMSP 78

  Fly    45 NTTQPVPG--TANVAGVP---GVPGVPGVPGPSLLQRAAQ-------QPGFQSSLRGTGAGGGGV 97
            ....|:.|  ....||.|   ..|..||:| |:::....:       ||...:..||.
Human    79 GNRMPMAGLQVGPPAGSPFGAAAPLRPGMP-PTMMDPFRKRLLVPQAQPPMPAQRRGL------- 135

  Fly    98 GSGGGSKRSNESRSLGGGGSKSDFATAKKKKKLAEKILPQKVRDLVPESQAYMDLLTFERKLDAT 162
                                        |::|:|:|:|||::|:||||||||||||.||||||.|
Human   136 ----------------------------KRRKMADKVLPQRIRELVPESQAYMDLLAFERKLDQT 172

  Fly   163 IMRKRLDIQEALKRPMKQKRKLRIFISNTFYPSK-EPTNDGEEGA---------VASWELRVEGR 217
            |.|||::||||:|:|:.|||||||:|||||.||| |..:.|..|.         ||||||||||:
Human   173 IARKRMEIQEAIKKPLTQKRKLRIYISNTFSPSKAEGDSAGTAGTPGGTPAGDKVASWELRVEGK 237

  Fly   218 LLEDGKGDPNTKIKRKFSSFFKSLVIELDKELYGPDNHLVEWHRTHTTQETDGFQVKRPGDRNVR 282
            ||:|     .:|.|||||||||||||||||||||||||||||||..|||||||||||||||.||:
Human   238 LLDD-----PSKQKRKFSSFFKSLVIELDKELYGPDNHLVEWHRMPTTQETDGFQVKRPGDLNVK 297

  Fly   283 CTILLLLDYQPLQFKLDPRLARLLGVHTQTRPVIISALWQYIKTHKLQDAHEREYINCDKYLEQI 347
            ||:||:||:||.|:|||||||||||||||||..|:.|||.|||.::|||.||||||||::|..||
Human   298 CTLLLMLDHQPPQYKLDPRLARLLGVHTQTRAAIMQALWLYIKHNQLQDGHEREYINCNRYFRQI 362

  Fly   348 FSCQRMKFAEIPQRLNPLLHPPDPIVINHFIE-SGAENKQTACYDIDVEVDDTLKNQMNSFLMST 411
            |||.|::|:|||.:|..||..||||||||.|. ...:.|:||||||||||||.||.||::||.||
Human   363 FSCGRLRFSEIPMKLAGLLQHPDPIVINHVISVDPNDQKKTACYDIDVEVDDPLKAQMSNFLAST 427

  Fly   412 ASQQEIQGLDTKIHETVDTINQMKTNREFFLSFAKDPQMFIHRWIISETRDLKLMTDVAGNPEEE 476
            .:||||..||.|||||:::|||:||.|:|.|||:.|||.||..|:.|:.||||::|||.||||||
Human   428 TNQQEIASLDVKIHETIESINQLKTQRDFMLSFSTDPQDFIQEWLRSQRRDLKIITDVIGNPEEE 492

  Fly   477 RRAEFYYQPWTHEAVSRYFFTKVNQKRAELEQALGIR 513
            |||.||:|||..|||.|:.|.||.|:|.||||.||||
Human   493 RRAAFYHQPWAQEAVGRHIFAKVQQRRQELEQVLGIR 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bap60	NP_511143.2	SWIB_BAF60A	295..371	CDD:349493	51/75 (68%)
SMARCD2	NP_001091896.1	PHA03201	61..>148	CDD:165468	24/123 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	205..226		5/20 (25%)
		SWIB_BAF60B	307..386	CDD:349494	53/78 (68%)