DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Bap60 and smarcd3a

DIOPT Version :9

Sequence 1:	NP_511143.2	Gene:	Bap60 / 32268	FlyBaseID:	FBgn0025463	Length:	515	Species:	Drosophila melanogaster
Sequence 2:	XP_005163573.1	Gene:	smarcd3a / 564652	ZFINID:	ZDB-GENE-070912-491	Length:	518	Species:	Danio rerio

Alignment Length:	519	Identity:	319/519 - (61%)
Similarity:	376/519 - (72%)	Gaps:	56/519 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 GMRPYPPPGASFPPRGFPLHP------NTTQPVPGTANVAGVPG----VPGVPGVPGPSLLQRAA 78
            |:||....||..|.:|.|:.|      .|.|..||..|.|..|.    .|..|..| ||:..|:.
Zfish    25 GVRPGMTSGARMPHQGAPMGPPGPPYGGTPQIRPGMPNPALDPNRKRPAPTQPVQP-PSVQNRSR 88

  Fly    79 QQP-GFQSSLRGTGAGGGGVGSGGGSKRSNE--SRSLGGGGSKSDFATAK--KKKKLAEKILPQK 138
            ::| ||.:                    :||  :|.:....::||.|...  |::|:|:|||||:
Zfish    89 KKPLGFPA--------------------ANEISARQMDMREAQSDPAIGSNAKRRKMADKILPQR 133

  Fly   139 VRDLVPESQAYMDLLTFERKLDATIMRKRLDIQEALKRPMKQKRKLRIFISNTFYPSKEPTNDGE 203
            :|:||||||||||||.||||||.||||||:|||||||||||||||||::|||||.|:|..|.| .
Zfish   134 IRELVPESQAYMDLLAFERKLDQTIMRKRVDIQEALKRPMKQKRKLRLYISNTFNPAKPDTED-S 197

  Fly   204 EGAVASWELRVEGRLLEDGKGDPNTKIKRKFSSFFKSLVIELDKELYGPDNHLVE---------- 258
            ||::|||||||||:||:    ||. |.|||||||||||||||||:||||||||||
Zfish   198 EGSIASWELRVEGKLLD----DPG-KQKRKFSSFFKSLVIELDKDLYGPDNHLVEIALKHAAKIG 257

  Fly   259 ---WHRTHTTQETDGFQVKRPGDRNVRCTILLLLDYQPLQFKLDPRLARLLGVHTQTRPVIISAL 320
               ||||.|||||||||||||||.|||||:||:|||||.|||||||||||||:|||||..||.||
Zfish   258 ETQWHRTPTTQETDGFQVKRPGDVNVRCTLLLMLDYQPPQFKLDPRLARLLGIHTQTRSCIIQAL 322

  Fly   321 WQYIKTHKLQDAHEREYINCDKYLEQIFSCQRMKFAEIPQRLNPLLHPPDPIVINHFIE-SGAEN 384
            |||:||:||||:||:||||||||.:|||.|.|:||.||||||..||.|||||||||.|. ...:.
Zfish   323 WQYVKTNKLQDSHEKEYINCDKYFQQIFDCPRLKFCEIPQRLTNLLLPPDPIVINHIISVDPNDQ 387

  Fly   385 KQTACYDIDVEVDDTLKNQMNSFLMSTASQQEIQGLDTKIHETVDTINQMKTNREFFLSFAKDPQ 449
            |:||||||||||||.||.|||.||:|||:||||..||.|||||:::|||:|..|:|.|||::||:
Zfish   388 KKTACYDIDVEVDDPLKGQMNGFLLSTANQQEIASLDNKIHETIESINQLKIQRDFMLSFSRDPK 452

  Fly   450 MFIHRWIISETRDLKLMTDVAGNPEEERRAEFYYQPWTHEAVSRYFFTKVNQKRAELEQALGIR 513
            .:|..||.|:.||||||||..||||||||||||.|||:.|||||||:.|:.|:|.||||||.:|
Zfish   453 GYIQDWICSQNRDLKLMTDTVGNPEEERRAEFYNQPWSQEAVSRYFYCKIQQRRQELEQALAMR 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Bap60	NP_511143.2	SWIB_BAF60A	295..371	CDD:349493	58/75 (77%)
smarcd3a	XP_005163573.1	Rsc6	201..411	CDD:227818	156/214 (73%)
smarcd3a	XP_005163573.1	SWIB	297..368	CDD:280380	54/70 (77%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	280	1.000	Domainoid score	I1639
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	629	1.000	Inparanoid score	I828
OMA	1	1.010	-	-		QHG55104
OrthoDB	1	1.010	-	-		D1027566at2759
OrthoFinder	1	1.000	-	-		FOG0000716
OrthoInspector	1	1.000	-	-		otm26106
orthoMCL	1	0.900	-	-		OOG6_100964
Panther	1	1.100	-	-	O	PTHR13844
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1401
SonicParanoid	1	1.000	-	-		X681
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	12.010