DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4332 and AT5G23575

DIOPT Version :9

Sequence 1:	NP_572861.1	Gene:	CG4332 / 32267	FlyBaseID:	FBgn0030456	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_680213.1	Gene:	AT5G23575 / 832423	AraportID:	AT5G23575	Length:	593	Species:	Arabidopsis thaliana

Alignment Length:	569	Identity:	198/569 - (34%)
Similarity:	288/569 - (50%)	Gaps:	71/569 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SISTLLGVAFLAYIGHSIYQ----------MSQLFTTLQCSGVPC-----------YTSFLADRP 48
            :||.::.:|...|.....:.          .|||.|.|...|...           :..|..||
plant    31 TISGIVRIAVFWYFASKFFSPKQKPMDPTAPSQLMTNLFHKGESLDMWFYLSEQEKFNDFGNDR- 94

  Fly    49 RLQLALFSSLSRSPIATEVRDLYKAKRFDYDQNFEHDFEVDVPLRT-RRNGSLYLHVVLALEGEP 112
                ||:...:..|.|....:..:.|...|           .|..| :.|||||.|:..|..|.|
plant    95 ----ALYWHETNIPYAVWTPESIRTKSLTY-----------YPSETLQNNGSLYAHIFFARSGFP 144

  Fly   113 L-----EWRSLRRDGPTVVHTMSLTDYIVPRAEAFK---LLG---DSEKGAAAAVQEKEKKKAST 166
            :     |::.|.    :...|.::..|. |:.:..|   |||   ||::......:..:||....
plant   145 IDPTDPEYQPLN----SFSRTHAVATYF-PKQKKNKKKSLLGSPKDSDESEPEVEKVGDKKSDPK 204

  Fly   167 TGRPSTHI---RSNVYVTLLNDLYSVSQADVPPEMAPLIRVN-RNQQILPILQTDTFNTRLKDLV 227
            ...|...|   :.||.:.|::|....||..|||.:||.:.|. ......|.:..:.|.......:
plant   205 EEVPVEWISLWKPNVTINLVDDFTHYSQNGVPPNIAPHLLVEPTTGNYYPTIYFNEFWLLRDKFI 269

  Fly   228 PVTRNTTEFTFSFHYKPVGVGKLRLMLLMEHATQALLTIG-FATKDIDEVKGIFSDTNVYLLCGT 291
            ||....:|...:....|:.:.|.:|...::.:.|...:.| ....:.||:|.:|.:.|.|||..|
plant   270 PVNETVSELPLNLEISPISMMKWQLFQQVDQSFQMQRSYGSMLDGESDELKKVFLEGNPYLLGIT 334

  Fly   292 IFVSSIHMLFDFLSFKNDVAFWRKKQSYEGLSSRTTMWRAFSQIVIFFYLLDENTSYLVLVPVGL 356
            :|||.:|.:||||:||||:.||.|.:|.||||:::.:.....|.|||.||||.:||:::|...|:
plant   335 MFVSMLHSVFDFLAFKNDIQFWNKNKSMEGLSAKSVVLNFICQFVIFLYLLDNDTSWMILASSGV 399

  Fly   357 GTLIELWKCKKIFRLELSFSGLVRRKLEQVDRRNGDQAGVKSGQLAEEQKTDQFDRQGMRYLSYL 421
            |..||.||..|..|:|:..||::.| |...||.:           ....||.::|...:::|||:
plant   400 GVCIEFWKIGKAMRIEVDRSGMIPR-LRFHDRES-----------YASNKTKEYDDIAIKFLSYV 452

  Fly   422 LYPLCICGAVYSLLYQPHRSWYSWTLNSLVNGVYAFGFLFMLPQLFVNYKLKSVAALPWRAFMYK 486
            |..|.|..::|||.|:.|:|||||.|:||.:.||.|||:.|.||||:||||||||.||||...||
plant   453 LLLLVIGLSIYSLAYERHKSWYSWILSSLTSCVYMFGFIMMCPQLFINYKLKSVAHLPWRQMTYK 517

  Fly   487 AFNTFIDDFFAFIITMPTAHRVACLRDDIVFIIYLYQRWLYPVDKSRLD 535
            ..||.|||.|||:|.||..||::..|||::|:|||||||:|||||:|::
plant   518 FLNTIIDDLFAFVIKMPILHRLSVFRDDVIFLIYLYQRWVYPVDKTRVN 566

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4332	NP_572861.1	CLPTM1	10..435	CDD:283294	131/462 (28%)
AT5G23575	NP_680213.1	CLPTM1	32..467	CDD:398952	134/467 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106937at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100901
Panther	1	1.100	-	-	O	PTHR21347
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.780