Protein Alignment CG4332 and CLPTM1L

DIOPT Version :9

• Sequence 1: NP_572861.1
• Gene: CG4332 / 32267
• FlyBaseID: FBgn0030456
• Length: 562
• Species: Drosophila melanogaster
• Sequence 2: XP_024301989.1
• Gene: CLPTM1L / 81037
• HGNCID: 24308
• Length: 566
• Species: Homo sapiens
• Alignment Length: 566
• Identity: 253/566 - (44%)
• Similarity: 346/566 - (61%)
• Gaps: 58/566 - (10%)

  Fly     5 SISTLLGVAFLAYIGHSIYQMSQLFTTLQCSG-VPCYTSFLADRPRLQLALFSSLSRSPIATE-- 66
            |.::|:...|:.|:.|:.:.|..:..|..||| ..|...:||.||:|||::::: :||.:..|
Human     7 SFTSLVVGVFVVYVVHTCWVMYGIVYTRPCSGDANCIQPYLARRPKLQLSVYTT-TRSHLGAENN 70

  Fly    67 VRDLYKAKRFDYDQNFEHDFEVDVPLRTRRNGSLYLHVVLALEGEPLEWRSLRRDGPTVVHTMSL 131
            :..:...:.||.:..||....|.||.:||.||:||.::.|...| .|.|    .||..|.....|
Human    71 IDLVLNVEDFDVESKFERTVNVSVPKKTRNNGTLYAYIFLHHAG-VLPW----HDGKQVHLVSPL 130

  Fly   132 TDYIVPRAEAFKLL-GDSEKGAAAAVQEKEKKKASTTGRPSTHIRSNVYVTLLNDLYSVSQADVP 195
            |.|:||:.|...|| |:|:....    |.|||..|....|.:|.|..:.:.::.|.:....:.:|
Human   131 TTYMVPKPEEINLLTGESDTQQI----EAEKKPTSALDEPVSHWRPRLALNVMADNFVFDGSSLP 191

  Fly   196 PEM---APLIRVNRNQQILPILQTDTFNTRLKDLVPVTRNTTEFTFSFHYKPVGVGKLRLMLLME 257
            .::   ..:|::.:....||||..|..:.|:|||:.:.|:|||...:..|..|.:|:||..:.|:
Human   192 ADVHRYMKMIQLGKTVHYLPILFIDQLSNRVKDLMVINRSTTELPLTVSYDKVSLGRLRFWIHMQ 256

  Fly   258 HATQALLTIGFATKDIDEVKGIFSDTNVYLLCGTIFVSSIHMLFDFLSFKNDVAFWRKKQSYEGL 322
            .|..:|...||:.||.|||||||.|||:|.|..|.||::.|:|||||:||||::||:||:|..|:
Human   257 DAVYSLQQFGFSEKDADEVKGIFVDTNLYFLALTFFVAAFHLLFDFLAFKNDISFWKKKKSMIGM 321

  Fly   323 SSRTTMWRAFSQIVIFFYLLDENTSYLVLVPVGLGTLIELWKCKKIFRLELSFSGLVRRKLEQVD 387
            |::..:||.||.:|||.:||||.||.|||||.|:|..|||||.||..::.:.:.||:..
Human   322 STKAVLWRCFSTVVIFLFLLDEQTSLLVLVPAGVGAAIELWKVKKALKMTIFWRGLMPE------ 380

  Fly   388 RRNGDQAGVKSGQLAEEQKTDQFDRQGMRYLSYLLYPLCICGAVYSLLYQPHRSWYSWTLNSLVN 452
                .|.|..|   ..|:||:::|.|.|:||||||||||:.|||||||...::|||||.:||.||
Human   381 ----FQFGTYS---ESERKTEEYDTQAMKYLSYLLYPLCVGGAVYSLLNIKYKSWYSWLINSFVN 438

  Fly   453 GVYAFGFLFMLPQLFVNYK----------------------------LKSVAALPWRAFMYKAFN 489
            |||||||||||||||||||                            |||||.|||:||.|||||
Human   439 GVYAFGFLFMLPQLFVNYKVRRCVLPAARPPSPVLPTADLGLSLLFQLKSVAHLPWKAFTYKAFN 503

  Fly   490 TFIDDFFAFIITMPTAHRVACLRDDIVFIIYLYQRWLYPVDKSRLD 535
            |||||.|||||||||:||:||.|||:||::||||||||||||.|::
Human   504 TFIDDVFAFIITMPTSHRLACFRDDVVFLVYLYQRWLYPVDKRRVN 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4332	NP_572861.1	CLPTM1	10..435	CDD:283294	170/431 (39%)
CLPTM1L	XP_024301989.1	CLPTM1	22..421	CDD:310296	168/421 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160128
Domainoid	1	1.000	297	1.000	Domainoid score	I1469
eggNOG	1	0.900	-	-		E1_KOG2489
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12767
Inparanoid	1	1.050	473	1.000	Inparanoid score	I1516
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47987
OrthoDB	1	1.010	-	-		D1106937at2759
OrthoFinder	1	1.000	-	-		FOG0007284
OrthoInspector	1	1.000	-	-		oto88856
orthoMCL	1	0.900	-	-		OOG6_100901
Panther	1	1.100	-	-	LDO	PTHR21347
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5387
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.770