DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4318 and zbtb43

DIOPT Version :9

Sequence 1:	NP_572860.2	Gene:	CG4318 / 32266	FlyBaseID:	FBgn0030455	Length:	236	Species:	Drosophila melanogaster
Sequence 2:	NP_001103494.1	Gene:	zbtb43 / 557590	ZFINID:	ZDB-GENE-060526-378	Length:	410	Species:	Danio rerio

Alignment Length:	176	Identity:	48/176 - (27%)
Similarity:	78/176 - (44%)	Gaps:	35/176 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 EMNYEEEGSN--DSDVELIEPVD--GSQEMETIDLTIDSPGDNVENMCPNS-------NSNGNGN 134
            |.:::|:.:.  |.|....||:|  || .||....|    ||.:.|  |.|       .:|.:|.
Zfish   239 EDSFDEKLTECLDRDCTYEEPLDFYGS-SMEGFSQT----GDELSN--PESKEKLQADGNNTDGP 296

  Fly   135 VSQSSAQKDTKK-----KMLKKTHKCNICGKYFMLPAHLKCHMWVHAREKPYKCLQCSQSYAQIR 194
            ..:|.|..:...     .::.|.:.|. |||.|...:....||.:|...:|:.|..|.:|:....
Zfish   297 KDESPADSEQTSHSGFASVVYKLYPCQ-CGKSFTHKSQRDRHMSMHLGLRPFGCAVCGKSFKMKH 360

  Fly   195 GLRRHERVHSSRPELRSYKCSRCPK------IFNRNSA--LKNHET 232
            .|..|.::|:.   ::.|:||.|.|      .|||:::  .|.|:|
Zfish   361 HLVGHMKIHTG---IKPYECSLCSKRFMWRDSFNRHTSTCAKAHQT 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4318	NP_572860.2	zf-AD	5..>64	CDD:285071
		C2H2 Zn finger	155..175	CDD:275368	7/19 (37%)
		zf-H2C2_2	167..192	CDD:290200	7/24 (29%)
		COG5048	<179..>236	CDD:227381	18/62 (29%)
		C2H2 Zn finger	183..203	CDD:275368	5/19 (26%)
		C2H2 Zn finger	214..234	CDD:275368	10/27 (37%)
zbtb43	NP_001103494.1	BTB	23..123	CDD:279045
		BTB	34..124	CDD:197585
		C2H2 Zn finger	323..341	CDD:275368	6/18 (33%)
		C2H2 Zn finger	349..369	CDD:275368	5/19 (26%)
		zf-H2C2_2	361..384	CDD:290200	8/25 (32%)
		C2H2 Zn finger	377..396	CDD:275368	7/18 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170585832
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930