Protein Alignment CG4318 and topi

DIOPT Version :10

• Sequence 1: NP_572860.2
• Gene: CG4318 / 32266
• FlyBaseID: FBgn0030455
• Length: 236
• Species: Drosophila melanogaster
• Sequence 2: NP_649945.1
• Gene: topi / 41199
• FlyBaseID: FBgn0037751
• Length: 814
• Species: Drosophila melanogaster
• Alignment Length: 178
• Identity: 44/178 - (24%)
• Similarity: 62/178 - (34%)
• Gaps: 67/178 - (37%)

  Fly   121 ENMC------PNSNSNG-----------------NGNVSQSSAQKDTKKKMLKKT---------- 152
            |:.|      |..|.||                 :..::.|..:...|||..|:|
  Fly   446 EHRCTSFHYFPRLNENGKKLLLPCDFCDVNFEFAHDFLAHSEEKHLNKKKREKETRNTGAGRIRQ 510

  Fly   153 HKCNICGKYFM----LPAHLKCHMWV---------------------------HAREKPYKCLQC 186
            :.|:||||.:.    |..||:.|..|                           |..|:||.||.|
  Fly   511 YLCDICGKSYTQSSHLWQHLRFHQGVKPFVCQEENCDRKFTIRPDLNDHIRKCHTGERPYLCLVC 575

  Fly   187 SQSYAQIRGLRRHERVHSSRPELRSYKCSRCPKIFNRNSALKNHETMH 234
            .:.:.......:|..:|...   |.|:|..|.|.|.|..|||||:.:|
  Fly   576 GKRFLTGSVFYQHRLIHRGE---RRYECEECGKRFYRADALKNHQRIH 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4318	NP_572860.2	zf-AD	5..77	CDD:462262
		C2H2 Zn finger	155..175	CDD:275368	10/50 (20%)
		C2H2 Zn finger	183..203	CDD:275368	4/19 (21%)
		C2H2 Zn finger	214..234	CDD:275368	10/19 (53%)
topi	NP_649945.1	C2H2 Zn finger	230..250	CDD:275370
		C2H2 Zn finger	277..297	CDD:275370
		C2H2 Zn finger	431..453	CDD:275368	2/6 (33%)
		COG5048	<450..647	CDD:227381	42/174 (24%)
		C2H2 Zn finger	469..490	CDD:275368	1/20 (5%)
		C2H2 Zn finger	513..564	CDD:275368	10/50 (20%)
		C2H2 Zn finger	541..561	CDD:275368	0/19 (0%)
		C2H2 Zn finger	572..592	CDD:275368	4/19 (21%)
		C2H2 Zn finger	600..620	CDD:275368	10/19 (53%)
		zf-H2C2_2	612..637	CDD:463886	6/9 (67%)
		C2H2 Zn finger	628..646	CDD:275368