DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4318 and klu-2

DIOPT Version :9

Sequence 1:	NP_572860.2	Gene:	CG4318 / 32266	FlyBaseID:	FBgn0030455	Length:	236	Species:	Drosophila melanogaster
Sequence 2:	NP_491843.3	Gene:	klu-2 / 172339	WormBaseID:	WBGene00022592	Length:	386	Species:	Caenorhabditis elegans

Alignment Length:	166	Identity:	43/166 - (25%)
Similarity:	63/166 - (37%)	Gaps:	28/166 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 MNYEEEGS--------NDSDVELIEPV----DGSQEMETIDLTIDSPGDNVENMCPNSNSNGNGN 134
            :|.|.|.|        :.|..|:::.|    .||          .|..:|:.|....:.:...|:
Worm   177 LNIEHEKSAFEIVSCHHQSAEEILQRVRLGTSGS----------TSSANNLRNSLSEATTTTTGS 231

  Fly   135 VSQSSAQKDTKKKMLKKTHKCNICGKYFMLPAHLKCHMWVHAREKPYKCLQCSQSYAQIRGLRRH 199
            |..:|...|..   ....:.|.||.|.|..|..|..|...|..|||:||..|.:.:::...||.|
Worm   232 VESTSGTADGS---APGQYYCFICEKDFRRPDILSRHTRRHTGEKPFKCEDCGRFFSRSDHLRTH 293

  Fly   200 ERVHSSRPELRSYKCSRCPKIFNRNSALKNHETMHH 235
            .|.|:..   :.|.|..|.....|...|..|.:..|
Worm   294 RRTHTDE---KPYHCCVCNYSARRRDVLTRHMSTRH 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4318	NP_572860.2	zf-AD	5..>64	CDD:285071
		C2H2 Zn finger	155..175	CDD:275368	8/19 (42%)
		zf-H2C2_2	167..192	CDD:290200	9/24 (38%)
		COG5048	<179..>236	CDD:227381	17/57 (30%)
		C2H2 Zn finger	183..203	CDD:275368	6/19 (32%)
		C2H2 Zn finger	214..234	CDD:275368	5/19 (26%)
klu-2	NP_491843.3	COG5048	216..>298	CDD:227381	25/84 (30%)
		C2H2 Zn finger	249..269	CDD:275368	8/19 (42%)
		zf-H2C2_2	262..286	CDD:290200	9/23 (39%)
		COG5048	273..>328	CDD:227381	17/57 (30%)
		C2H2 Zn finger	277..297	CDD:275368	6/19 (32%)
		zf-H2C2_2	289..314	CDD:290200	8/27 (30%)
		C2H2 Zn finger	305..324	CDD:275368	5/18 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166744
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930