DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32645 and CG4576

DIOPT Version :9

Sequence 1:	NP_727670.1	Gene:	CG32645 / 32264	FlyBaseID:	FBgn0052645	Length:	853	Species:	Drosophila melanogaster
Sequence 2:	NP_650495.1	Gene:	CG4576 / 41914	FlyBaseID:	FBgn0038366	Length:	676	Species:	Drosophila melanogaster

Alignment Length:	705	Identity:	149/705 - (21%)
Similarity:	244/705 - (34%)	Gaps:	204/705 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   225 RIIYVGMCL-PSSCSIADI----------GQMSSRAHVELPSRDLRVLDIRVPTDKEFNIWADK- 277
            |.:|.|:|| ....|:|.:          |.:|..|.|.:      .||:       |::.|:.
  Fly    90 RQLYFGLCLRECEASLAGLNKSELEALQAGLLSENAKVNV------YLDL-------FSMEANNR 141

  Fly   278 -------TFCLL---------IVVSSIV--------------------------LGLICCGTLFE 300
                   ..||.         ::..|:|                          |.|.|.|:|.:
  Fly   142 QRHQRLTNACLNWRLQRRGFGVLAKSVVEYCDEAGHQVEDDAWNLTFYGILGTLLVLACLGSLVD 206

  Fly   301 IYLRRKLKEALRRQDKEMMNNSETSSGIGCASSDYSDTMTAHDDPLKQSDHSQSSNSLKQLDALV 365
            ::|:|                                  :.||..||:.||.::
  Fly   207 LHLKR----------------------------------SRHDKMLKERDHYKT----------- 226

  Fly   366 LNLPPNDNDSGNGHHHDHDAEHDHHDHHRSGSNNSNSDEHLEGHLHEPEKLSIYSELLLSFSAIT 430
               ||.                                             |...::||:||...
  Fly   227 ---PPK---------------------------------------------STAQQVLLTFSVAR 243

  Fly   431 NF---NAICDRNVGADT--IPCIHGLRAFSMAWVILGHTCIVVFKYSDNMEMRKEVEQNFFFQA- 489
            |:   |......:|.:.  :.|   .:.|:|..||..||..|:  |...:...::.|:.....|
  Fly   244 NWYRLNQEPSGKIGRELRFLDC---FKFFAMFMVIFAHTNWVI--YESAISNPQDPERLLHTAAG 303

  Fly   490 --ITNGPFSVDTFFFISGFL--ISYIYFRTNAKGKLNKLSKGANEFTAGTAHFFGLVAYRFMRLT 550
              :.:|.....|||.|||.|  |:::....:.:.|.:..|.|.....     |.....:|::|||
  Fly   304 TLLVSGSLITVTFFVISGLLLTINWLAVSRSLESKKDTWSFGQYALL-----FVKFNIFRYIRLT 363

  Fly   551 APYLFVL---GVVQVTMKYLATYSIFDPPTMDHITCPDYWWRNILYINTLFPVDEMCMLWSWYLA 612
            .||.|||   ||............||:   .:.:.|...||.|:||:|.....||.|:|..||||
  Fly   364 VPYAFVLLMSGVYFENAGGPLWRHIFE---REQLACRRNWWTNLLYVNNFVRTDERCLLQGWYLA 425

  Fly   613 NDTQFYMIGAIILIVGVRHFKLSAITTLVFLVLSWITTAVIAFTNNH------RPNTDDPLAL-- 669
            .||..:::..::|::|.|..:.|.......|.|..:...|:.:..|:      .|.|.....:
  Fly   426 ADTHSFVLSLVLLMLGHRFVRWSKQLYAGILGLFVVVPMVLTYAMNYYPIFVPTPQTQKDSFIGD 490

  Fly   670 --FDKIYDKPWTRLGPYLIGMAVGWI---LFRTNCKIRLPKLTVATAWTLAMLNLFVL-----VF 724
              |.:.|...:...|.|..|:....:   |.....|:|..|......:||..:.:..|     :|
  Fly   491 RQFTEFYTSSFMNFGSYFCGVLAALVYDQLALKQYKLRELKSFQLLWFTLIPVGILWLFSAHPIF 555

  Fly   725 GLYKADLSQFTAAAYSSLSHSAWALSLAWITIACSTGYGGYINSLLSAPCLYPFSRVTYCAYLVH 789
            ..|....|....|.|:.|..:.|...|....:..::..|.........|......|:||.|::||
  Fly   556 QHYYVTPSAIWGALYAGLQRNIWGFGLGIFIVGMASKVGWIFRKFCCLPIFRILGRLTYGAFIVH 620

  Fly   790 PIVIRSMALNSDAPLHLGGDLMVVMFFGLTVASYFLSFVVSMSFEAPVVTMLKIL 844
            .:|.|.:......|::.|..:|....|.....||..||::::..|.||.:.||::
  Fly   621 LLVARIVLATVREPIYFGTGMMFAFIFFTVTVSYLCSFLLAIFLELPVSSFLKLM 675

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32645	NP_727670.1	NRF	121..272	CDD:214781	13/57 (23%)
		Acyl_transf_3	445..831	CDD:280013	102/411 (25%)
		OafA	450..853	CDD:224748	106/421 (25%)
CG4576	NP_650495.1	Acyl_transf_3	260..657	CDD:280013	100/409 (24%)
CG4576	NP_650495.1	OafA	303..668	CDD:224748	92/372 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910