DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32645 and CG11353

DIOPT Version :9

Sequence 1:	NP_727670.1	Gene:	CG32645 / 32264	FlyBaseID:	FBgn0052645	Length:	853	Species:	Drosophila melanogaster
Sequence 2:	NP_647915.1	Gene:	CG11353 / 38560	FlyBaseID:	FBgn0035557	Length:	754	Species:	Drosophila melanogaster

Alignment Length:	891	Identity:	201/891 - (22%)
Similarity:	355/891 - (39%)	Gaps:	198/891 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MMRRTLVLAMLLSLLATPQAAIDKDDG--KFPPGRHNLSSA-PDQHNVIN----LSLHGDLTAAT 58
            :|...|.|..:|:..|:.|:|......  ::.....|.|.| ||:..:::    :.:|.
  Fly    17 LMLLGLWLGSVLAKGASNQSATTNSHAWQRYHSQALNASPALPDELEILDAPSTIEIHS------ 75

  Fly    59 LLPHVDPKLSYDLSQTRRLRDALNVFDLAVLAAQWGQVESSGGVSANCSRDMRSYLGGLSDAKMW 123
              ||          :|...|.:: :|.|.       :|.:...||..|...:|....|:...:.|
  Fly    76 --PH----------ETHLTRTSV-IFGLT-------KVANESSVSQKCHAQLRQMQRGILGKQPW 120

  Fly   124 AVKMDDASGHYTSGFFYGNNYWMGSLALCDAIDDGQIVAPGKDNSSSAASSPESETKNSGLPFAA 188
            |:|:.||||...|||.||.|||:||...|..:.                           .|...
  Fly   121 AMKVLDASGTKPSGFVYGQNYWLGSREACRGVQ---------------------------RPVGI 158

  Fly   189 AHTQGYSSVYN-----APPPFVPGFYVIKMQLNETLPTQV------LRIIYVGMCLPSSCSIADI 242
            ..::.:..|.:     ...||...:.|:.::.|.  |.||      .:||::|:||||:||..::
  Fly   159 TLSKNFDRVMHYGIITQQAPFDMDYRVLYLRHNS--PWQVEIKLMSEQIIHIGLCLPSACSSVEV 221

  Fly   243 ----------GQMSSRAHVELPSRDLRVLDIRVPTDKEFNIWADKTFCLLIVVSSIVLGLICCGT 297
                      |..:.....::....:.:.|:::..:    .:...:|.||:....:.:.|:.|.
  Fly   222 QSLAQDYVAGGMFTENEIFDIKPEVVYMKDLQLKDE----FFERASFRLLVACVLLTVTLMFCA- 281

  Fly   298 LFEIYLRRKLKEALRRQDKEMMNNSETSSGIGCASSDYSDTMTAHDDPLKQSDHSQSSNSLKQLD 362
                                                              |..|:.|......:|
  Fly   282 --------------------------------------------------QQLHATSKMPSISVD 296

  Fly   363 ALVLNLPPNDNDSGNGHHHDHDAEHDHHDHHRSGSNNSNSDEHLEGHLHEPEKLSIYSELLLSFS 427
            .|..:|.|.:::...|                     .||       |.:.|:|..|   :..:.
  Fly   297 PLDRDLAPAESEIWRG---------------------LNS-------LLQIERLQRY---VTCWD 330

  Fly   428 AITNFNAI-CDRNVGADTIPCIHGLRAFSMAWVILGHTCIVVFKY--SDNMEMRKEVEQNFFFQA 489
            ...|:..| ..|...|:.||.::|||:....|:::.|  :|.|.|  ..|..:.....:..|||.
  Fly   331 VPGNWAKIFAIRENTANEIPLMNGLRSVCAIWIMVFH--VVWFMYFTVHNKTVLISYAEQAFFQY 393

  Fly   490 ITNGPFSVDTFFFISGFLISYIYFRTNAKGKLNKLSKGANEFTAGTAHFFGLVAYRFMRLTAPYL 554
            :::.|..||.||.|||||.::.:.|.:.  :|..:.:  |.|:.....|..|:.:|::||...||
  Fly   394 VSSAPLLVDVFFTISGFLQTFNFLRNSR--QLEAVRQ--NSFSENLKLFGKLLFHRYLRLGPLYL 454

  Fly   555 FVLGVVQVTMKYLATYSIFDPPTMDHIT------CPDYWWRNILYINTLFPVDEMCMLWSWYLAN 613
            .|:..|.:...|:...|::      ||.      |..:||||:|:|..||...:||..|||.||.
  Fly   455 VVMATVDLVYAYIGDVSVY------HINERFDEMCTRHWWRNLLFIQNLFDHRDMCANWSWSLAC 513

  Fly   614 DTQFYMIGAIILIVGVRHFKLSAITTLVFLVLSWITTAV----IAFTNNHRPNTDDPLALFDKIY 674
            :.||:::...:|.:.|::.|:  :.:||  |.|::.|..    |..:...:.:.|...|...:||
  Fly   514 EMQFFILANALLFLYVKYPKV--VKSLV--VSSFVATIAWSYGIGLSIKFQLSFDAAFATGTEIY 574

  Fly   675 DKPWTRLGPYLIGMAVGWILFRTNCKIRLPKLTVATAWTLAMLNLFVLVFGLYKADLSQFTAAAY 739
            ..|:.|:.||::|....|:|.....::.:.:......|..|:...|..::...|.||....|...
  Fly   575 TSPFVRVLPYILGAVTAWLLQENRVQLEISEQKERACWHFALFVFFACIYSTVKRDLGPLMAITL 639

  Fly   740 SSLSHSAWALSLAWITIACSTGYGGYINSLLSAPCLYPFSRVTYCAYLVHPIVIRSMALNSDAPL 804
            ..:....::||:.|:......|.|.:.:.||.|......||::|..||::|:||......::|..
  Fly   640 FVMGRLFFSLSVCWMIARSCDGRGVWWSRLLEAKGFQHVSRLSYAIYLLNPLVIALFYSLTNAST 704

  Fly   805 HLGGDLMVVMFFGLTVASYFLSFVVSMSFEAPVVTMLKILSPSRKK 850
            |....::.|:..|..|..|..|.:.|::||.|...:..:|:..:.|
  Fly   705 HADPFMLCVVTCGFAVIVYLASILFSLAFELPFSNLSSLLNRRQSK 750

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32645	NP_727670.1	NRF	121..272	CDD:214781	38/171 (22%)
		Acyl_transf_3	445..831	CDD:280013	109/397 (27%)
		OafA	450..853	CDD:224748	113/413 (27%)
CG11353	NP_647915.1	NRF	118..243	CDD:214781	37/153 (24%)
		OafA	349..752	CDD:224748	115/418 (28%)
		Acyl_transf_3	352..729	CDD:280013	107/392 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm48834
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.920