DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32645 and CG9447

DIOPT Version :9

Sequence 1:	NP_727670.1	Gene:	CG32645 / 32264	FlyBaseID:	FBgn0052645	Length:	853	Species:	Drosophila melanogaster
Sequence 2:	NP_610243.4	Gene:	CG9447 / 35597	FlyBaseID:	FBgn0033110	Length:	656	Species:	Drosophila melanogaster

Alignment Length:	606	Identity:	143/606 - (23%)
Similarity:	241/606 - (39%)	Gaps:	109/606 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   298 LFEIYLRRKLKEALRRQDKEMMNNSETSSGIGCASSDYSDTMTAHDDPLKQSDHSQSSNSLKQ-- 360
            |...|.:...::|: ..|:::.|.....   ||.:..:|:..:.....|.:...|.|...||.
  Fly    88 LISYYDKVHRRDAM-NSDRDLFNKEVVK---GCLNQKFSEKFSLRTRSLIEYCVSASDKDLKMDL 148

  Fly   361 LD---------ALVLNLPPNDNDSGNGHHHDHDAEHDHHDHHRSGSNNSNSDEHLEGHLHEPEKL 416
            ||         .|.:.|..:..|                  :|....||...|
  Fly   149 LDLAFYGILVVILFITLCSSFLD------------------YRLSKMNSQKSE------------ 183

  Fly   417 SIYSE--------LLLSFSAITNFNAICD---RNVGADTIPCIHGLRAFSMAWVILGHTCIVVFK 470
            |.|.|        ||.|||.:.|::.:.:   .:...| :....|.|...:..||||||.:|...
  Fly   184 SFYREPLMDRRQRLLTSFSVVRNYHRLVEPYNSDFSRD-VSFFDGFRVIGVFVVILGHTLMVFMT 247

  Fly   471 YS-DNMEMRKEVEQNFFFQAITNGPFSVDTFFFISGFLISYIYF--RTNAKGKLNKLSKGANEFT 532
            .. :|.|..::....|......||...:..||.:||||: |:.|  |...:.|...|.
  Fly   248 VPIENPEFFEQFLFRFETSIFQNGSLVIQIFFVMSGFLL-YVKFTKRQQIQPKTGTLE------- 304

  Fly   533 AGTAHFFGLVAYRFMRLTAPYLFVL----GVVQVTMKYLATYSIFDPPTMDHIT------CPDYW 587
             ..|.:|.:.:||:.|| .|.|..|    |.:.|.::        :.|...|:|      |...|
  Fly   305 -CIAVYFRVFSYRYFRL-LPSLLALILFNGTLLVRLQ--------NGPFWRHLTEAERVFCRANW 359

  Fly   588 WRNILYINTLFPVDEMCMLWSWYLANDTQFYMIGAIILIVGVRHFKLSAITTLVFLVLSWITTAV 652
            |:|:.:: |...:::.|...:|||..|.|.:.:..|::|:..:|.||:.......|.|::...||
  Fly   360 WKNVFFV-TNHMLEDSCSHQTWYLGADMQLFELFLIVIIITKKHPKLTRTIYTTLLALAFAVPAV 423

  Fly   653 IAFT------NNHRPNTDDPLAL-----FDKIYDKPWTRLGPYLIGMAVGWILFRT---NCKIRL 703
            :.:.      .:.||.|...|..     |.::|...:|.||.||.|...|....|.   |.:: |
  Fly   424 LTYVLELDGIYHIRPETYRYLYFRHSDTFYQMYPPFYTNLGGYLFGFLCGHFYLRQRSGNVEL-L 487

  Fly   704 PKLTVATA-WTLAMLNLFVLVFG--LYKADLSQ--FTAAAYSSLSHSAWALSLAWITIACSTGYG 763
            ..|....| |.|.:..|.||..|  ..:.|.::  ...|.|:.:....|.|..|...|......|
  Fly   488 GHLKYDLAMWLLVLATLGVLFSGYIFIRQDFAKPSLWLALYAGIHKILWVLICAGFVILMCRKVG 552

  Fly   764 GYINSLLSAPCLYPFSRVTYCAYLVHPIVIRSMALNSDAPLHLGGDLMVVMFFGLTVASYFLSFV 828
            |......:.|...|.:|:::.::|.|.:|:|::|.|...|:::....::...|.:.:.:.|::.:
  Fly   553 GIAYDFCTLPAFRPLARISFQSFLWHIVVLRTVAGNFRQPVYVSSFFLLCNVFSVFILTQFVAAL 617

  Fly   829 VSMSFEAPVVTMLKILSPSRK 849
            |::..|.|.|.:|:.|....|
  Fly   618 VAVLLEYPFVEVLRCLIKPEK 638

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32645	NP_727670.1	NRF	121..272	CDD:214781
		Acyl_transf_3	445..831	CDD:280013	105/417 (25%)
		OafA	450..853	CDD:224748	111/432 (26%)
CG9447	NP_610243.4	Acyl_transf_3	222..611	CDD:280013	103/408 (25%)
CG9447	NP_610243.4	OafA	225..631	CDD:224748	108/425 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010