DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32645 and CG12990

DIOPT Version :9

Sequence 1:	NP_727670.1	Gene:	CG32645 / 32264	FlyBaseID:	FBgn0052645	Length:	853	Species:	Drosophila melanogaster
Sequence 2:	NP_573233.1	Gene:	CG12990 / 32747	FlyBaseID:	FBgn0030859	Length:	663	Species:	Drosophila melanogaster

Alignment Length:	821	Identity:	160/821 - (19%)
Similarity:	281/821 - (34%)	Gaps:	275/821 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 ANCSRDMRSYLGGLSDAKMWAVKMDDASGHYTSGFFYGNNYWMGSLALCDAIDDGQIVAPGKDNS 168
            :.|...:........|.:.||:|..||||...:.|..|...|:|:...|.|:::..:
  Fly    42 SKCEEQLLELRRAWQDHQSWALKAIDASGEGYANFMMGQRAWLGNRFTCRAVNEPML-------- 98

  Fly   169 SSAASSPESETKNSGL-----PFAAAHTQGYSSVYNAPPPFVPGFYVIKMQLNETLPTQVLRIIY 228
                  .:...||..|     |....:...|.. .|:|           .||..|:....|  ::
  Fly    99 ------QDMTIKNQRLLREMSPIQFHYLVAYIE-SNSP-----------WQLEVTIKANPL--LH 143

  Fly   229 VGMCLPSSCSIADIGQMSSRAHVELPSRDLRVLDIRVPTDKEFNIWADKTFCLLIVVSSIVLGLI 293
            :|:|||:||.:.::.|:..::..:..|.....:|.::...|:..:..:......:.:..:|||:.
  Fly   144 IGLCLPASCDVPEVEQLIRKSMAKEESFHCWDMDAKLAYAKKPELKTNFFDSGAVQIFFVVLGVT 208

  Fly   294 CCGTLFEIYLRRKLKEALRRQDKEMMNNSETSSGIG-----CASSDYSDTMTAHDDPLKQSDHSQ 353
            ...||                        ..:||:|     .|..|::|.......|:..|..::
  Fly   209 LLLTL------------------------AATSGLGKYSRILACFDFADNWRLAWKPVNPSQENR 249

  Fly   354 SSNSLKQLDALVLNLPPNDNDSGNGHHHDHDAEHDHHDHHRSGSNNSNSDEHLEGHLHEPEKLSI 418
            ..|.|:
  Fly   250 PVNGLR----------------------------------------------------------- 255

  Fly   419 YSELLLSFSAITNFNAICDRNVGADTIPCIHGLRAFSMAWVILGHTCIVVFKYSDNMEMRKEVEQ 483
               :|.:||.| ..:.|..:....|  |.:..|...|                  :|.||.
  Fly   256 ---VLTAFSLI-GVHVIWYKYFSVD--PSVEMLGKLS------------------SMTMRH---- 292

  Fly   484 NFFFQAITNGPFSVDTFFFISGFLISYIYFRTN-------AKGKLNKLSKGANEFTAGTAHFFGL 541
                   |..|..|:.||.:||:|....:.|..       :.|.|..:.:...||
  Fly   293 -------TYWPTMVEIFFVVSGYLTVLNFIRDEQLQKDIASDGILGNMRRYLREF---------- 340

  Fly   542 VAYRFMRLTAPYLFV---LGVVQVT-MKYLATYSIFDPPTMDHITCPDYWWRNILYINTLFPVDE 602
             .:|:.|| ||..||   :|||.:. .:.::...|.||  .|.: |.....||:.:|..|||:..
  Fly   341 -IHRYCRL-APLQFVIVLMGVVVIEYQRQVSVMQITDP--QDEL-CRLNAVRNVFFIQNLFPIQF 400

  Fly   603 MCMLWSWYLANDTQFYMIGAIILIVGVRH-----------FKLSAITTLVFL------------- 643
            ||..|:|.|..|.|.:|...::|.:..:|           ..:||:.::||:
  Fly   401 MCGSWTWSLGCDMQLHMTAMLLLFMHTKHPNMVKWIVRLLVVISALFSIVFMEVNEVGANFEEMY 465

  Fly   644 -------------VLSWITTAVIAFTNNHRPNTDDPLALFDKIYDKPWTRLGPYLIGMAVGWILF 695
                         :|::|.....||.......|.     ||.:....|.|||..   ..:|| |.
  Fly   466 HTNEWSYMSPLIRMLAYIIGGSYAFFQVKGTGTP-----FDLVMPNWWIRLGAI---ACIGW-LA 521

  Fly   696 RTNCKIRLPKLTVATAWTLAMLNLFVLVFGLYKADLSQFTAAAY-----------SSLSHSAWAL 749
            |.....:||.:::..::   |:.|.:||          .|||::           .|.:.:.|.|
  Fly   522 RQVTMDQLPAISIILSF---MVVLRILV----------STAASHLIICGTKPDNSDSYAPTRWLL 573

  Fly   750 SLAWITIACSTGYGGYINSLLSAPCLYPFSRVTYCAYLVHPIVIRSMALNSDAPLHLGGDLMVVM 814
                              :||.:..:...|:.||..||::||||..:..:....::....:|:::
  Fly   574 ------------------ALLQSEQVQRISKFTYAIYLLNPIVIMYVYHSFSNEVYPDNTMMIML 620

  Fly   815 FFGLTVASYFLSFVVSMSFEAPVVTMLKIL-----SPSRKK 850
            ....:|..|..:.|:::.||.|...:..::     ||::||
  Fly   621 AISCSVVCYLWAIVMTVLFEIPFNRLTSVMINSRSSPAKKK 661

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32645	NP_727670.1	NRF	121..272	CDD:214781	34/155 (22%)
		Acyl_transf_3	445..831	CDD:280013	96/444 (22%)
		OafA	450..853	CDD:224748	102/465 (22%)
CG12990	NP_573233.1	NRF	61..162	CDD:214781	31/128 (24%)
		Acyl_transf_3	251..637	CDD:280013	104/534 (19%)
		OafA	295..660	CDD:224748	94/419 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3700
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920