DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32645 and Oacyl

DIOPT Version :9

Sequence 1:	NP_727670.1	Gene:	CG32645 / 32264	FlyBaseID:	FBgn0052645	Length:	853	Species:	Drosophila melanogaster
Sequence 2:	NP_001099609.1	Gene:	Oacyl / 291549	RGDID:	1304731	Length:	676	Species:	Rattus norvegicus

Alignment Length:	794	Identity:	181/794 - (22%)
Similarity:	300/794 - (37%)	Gaps:	175/794 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 LAVLAAQWGQVESSGGVSANCSRDMRSYLGGLSD--AKMWAVKMDDASGHYTSGFFYGNNYWMGS 148
            ||.|.|.:..|..:..:|..|.:|...:|..|:.  .|.:|::|.|:.|...|....||...:||
  Rat     7 LACLHALFPFVSPARNISLKCMQDTDEFLSDLNSLKPKEYALRMYDSVGKLESNVLNGNVDRLGS 71

  Fly   149 LALCDAIDDGQIVAPGKDNSSSAASSPESETKNSGLPFAAAHTQGYSSVYNAPPPFVPGFYVIKM 213
            .:.|                 .:..|||...:..   :...|.....:.|:
  Rat    72 YSEC-----------------LSTQSPEGSFRGQ---YCKLHILQDGTDYS-------------- 102

  Fly   214 QLNETLPTQVLRIIYVGMCLPSSCSIADIGQMS--------SRAHVELPSRDLRVLDIRVPTDKE 270
                           ||:|:|.||:..|:..||        :.:.:| ||..|...|    :...
  Rat   103 ---------------VGVCVPDSCAEEDVTTMSQLDILRFRNTSFLE-PSLSLFTKD----SSSS 147

  Fly   271 FNIWAD-----------KTFCLLIVVSSIVLGLICCGTLFEIYLRRKLKEALRRQDKEMMNNSET 324
            ..|.|.           .:.||.|.:..:||.:  .||::.:                     ..
  Rat   148 CEIVARCAAGALKPDMFSSVCLFITLLGLVLPV--AGTVYMV---------------------AR 189

  Fly   325 SSGIGCASSDYSDTMTAHDD-PLKQSDHSQSSNSLKQLDALVLNLPPNDNDSGNGHHHDHDAEHD 388
            ..|:...::....|.|:.:. ||    .:..||..:...:..:.|||....|.....
  Rat   190 DWGLDLKAASVCGTPTSLESLPL----GNMESNRQRNRTSCQVQLPPPGPPSRGKRF-------- 242

  Fly   389 HHDHHRSGSNNSNSDEHLEGHLHEPEKLSIYSELLLSFSAITNFNAICDRNVGADTIPCIHGLRA 453
                                       |.....:|..||...|..|||:..:...|...::|:|.
  Rat   243 ---------------------------LGALDGVLQCFSWQKNMPAICNPELPGGTCQTLNGIRV 280

  Fly   454 FSMAWVILGHTC-IVVFKYSDN-MEMRKEVEQNFFFQAITNGPF--SVDTFFFISGFLISYIYFR 514
            .|:.|:|.|||. :..:...|| :|.:..|.:|..:....:|||  .|||||.|||:|.:..:.:
  Rat   281 LSLLWIISGHTSQMTAWLSLDNVLEWKARVPKNPLYLYSRSGPFYLGVDTFFLISGWLSARSFLK 345

  Fly   515 TNAKGKLNKLSKGANEFTAGTAHFFGLVAY---RFMRLTAPYLFVLGVVQVTMKYLATYSIFDPP 576
            .:           .|..|..|...  ::.|   ||.||...:|:.:.::.....::....:::..
  Rat   346 MH-----------QNTSTGITPKV--ILRYFLKRFTRLQLLHLYSVCLLVGFFSFVPWGPVWEVA 397

  Fly   577 TMDHITCPDYWWRNILYINTLFPVDEMCMLWSWYLANDTQFYMIGAIILIV-GVRHFKLSAITTL 640
            ......|.:.||.|:|.:|....|.:.|..|:||||:|.||:::..:|.:| |.....|..:..|
  Rat   398 QFHWDNCREVWWTNLLLLNNFLSVQKACNGWTWYLASDFQFHLMTPLIFLVHGKSKRALVLLGGL 462

  Fly   641 VFLVLSWITTAVIAFTNNHRPNTDDPLA--------LFDKIYDKPWTRLGPYLIGMAVGWILFRT 697
            :|||.|   ||....|..::.....|.|        .|.:.|.||:.|.||:|:|:.:...:...
  Rat   463 LFLVSS---TATALLTVAYKLPVSSPSAASENETVLYFSEYYTKPYCRCGPFLVGLFLSMFMHSD 524

  Fly   698 N-CKIRLPKLTVATAWTLAMLNLFVLVFGLYKAD----LSQFTAAAYSSLSHSAWALSLAWITIA 757
            : ..:...|:.....|..::..||.:|...|..|    .|...||.|.:|..:.||.::.|:..|
  Rat   525 HPTDVLRTKVQAVLGWAFSLTTLFAVVALAYVVDDTSPTSSVLAAIYQALHRTLWAAAVGWVIFA 589

  Fly   758 CSTGYGGYINSLLSAPCLYPFSRVTYCAYLVHPIVIRSMALNSDAPLHLGGDLMVVMFFGLTVAS 822
            |..|:||.:..|||.......:.::|..||||||||.......:..:|.....|..:|.|..|.:
  Rat   590 CQEGFGGPVKRLLSCGIWALPASISYACYLVHPIVIILYNGLQETLIHYTDTNMFYLFSGHCVLT 654

  Fly   823 YFLSFVVSMSFEAP 836
            :.....:::..|.|
  Rat   655 FLCGLALTLFIERP 668

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32645	NP_727670.1	NRF	121..272	CDD:214781	30/158 (19%)
		Acyl_transf_3	445..831	CDD:280013	110/406 (27%)
		OafA	450..853	CDD:224748	112/408 (27%)
Oacyl	NP_001099609.1	NRF	44..136	CDD:214781	26/141 (18%)
		OafA	275..674	CDD:224748	112/410 (27%)
		Acyl_transf_3	275..663	CDD:280013	110/403 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	153	1.000	Domainoid score	I4195
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	1	1.100	-	-	O	PTHR11161
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.820