DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32645 and oac-32

DIOPT Version :9

Sequence 1:	NP_727670.1	Gene:	CG32645 / 32264	FlyBaseID:	FBgn0052645	Length:	853	Species:	Drosophila melanogaster
Sequence 2:	NP_001300114.1	Gene:	oac-32 / 186125	WormBaseID:	WBGene00018708	Length:	707	Species:	Caenorhabditis elegans

Alignment Length:	830	Identity:	190/830 - (22%)
Similarity:	309/830 - (37%)	Gaps:	245/830 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 LNVFDLAVLAAQWGQV---ESSGGVSANCSRDMRSYLGGLS---------------DAK------ 121
            ||:  :...:|.|..|   :....:||.|..|..:::..|.               :||
Worm    13 LNI--IPTTSATWKDVIKPKPLDNLSAQCLNDTNTWINSLEIFGTLYAECIIMKKCNAKELKVLR 75

  Fly   122 --MWAVKMDDASGHYT-SGFFYGNNYWMGSLALCDAIDDGQ--------IVAPGKDNSSSAASSP 175
              ::||:..||.|.:. :|.......:.||...|..:...:        ::.|||:.||.|.|:.
Worm    76 DNLYAVQQLDAFGQFPGAGLLELKTLYDGSYQECQRVSGKKYDVNYCYLLLTPGKNVSSCAPSNS 140

  Fly   176 ESETKNSGLPFAAAHTQGYSSVYNAPPPFVPGFYVIKMQLNETLPTQVLRIIYVGMCLPSSCSIA 240
            :|                                     |...||   |||   .:|||.||:..
Worm   141 KS-------------------------------------LYSQLP---LRI---AVCLPDSCNHQ 162

  Fly   241 DI----GQMSSRAHVELPSRDLRVLDIRVPTDKEFNIWADKTFCLLIVVSSIVLGLICCGTLFEI 301
            |:    .::|     ..|.........:....|:...|....|.:::||.:.:..::       .
Worm   163 DMIDIFNELS-----PYPFTACSAYCTKNEVKKDTPFWGFSIFLIVMVVIAAIASIV-------D 215

  Fly   302 YLRRKLKEALRRQDKEMMNNSETSSGIGCASSDYSDTMTAHDDPLKQSDHSQSSNSLKQLDALVL 366
            |:|                  ||..|:.                      ||..|
Worm   216 YVR------------------ETVYGLS----------------------SQKEN---------- 230

  Fly   367 NLPPNDNDSGNGHHHDHDAEHDHHDHHRSGSNNSNSDEHLEGHLHEPEKLSIYSELLLSFSAITN 431
                                                              :.:.::||:||..||
Worm   231 --------------------------------------------------NTFFKILLTFSLWTN 245

  Fly   432 FN---AICDRNVG-ADTIPCIHGLRAFSMAWVILGHTCIVVFKYSDNMEMRKEVEQNFFFQAITN 492
            ..   ::.::..| ..::.||   |..||.||:.||:.:.:. .:|.:|...:....|:...:.|
Worm   246 AELLLSVKEQKSGFIKSLDCI---RLLSMCWVVTGHSFLYLI-LADTLEPVLDFPTYFWNHLLLN 306

  Fly   493 GPFSVDTFFFISGFLISYIYFRTNAKGKLNKLSKGANEFTAGTAHFFGLVAYRFMRLTAPYLFVL 557
            ...||||||.:||.:::|::|:|       ||:|...........|:   .:|::|||.|.:..:
Worm   307 AFVSVDTFFVLSGIVVAYLFFKT-------KLTKKTITSPMTWILFY---VHRYLRLTPPVMLFI 361

  Fly   558 GVVQVTMKYLATYSIFDPPTMDHI-----TCPDYWWRNILYINTLFPVDE------MCMLWSWYL 611
            |...|...|:  ...|....::.:     .|...||:|:||||..   |:      .|...:|||
Worm   362 GFFTVYTPYI--QGAFSASELNQMAPQAAACKTLWWQNLLYINNF---DDGNSQNSTCYGITWYL 421

  Fly   612 ANDTQFYMIGAIILIVGVRHFKLSAITTLVF--LVLSWITTAVIAFTNNHRPN---TDDPLALFD 671
            |.|||.|::..|:|:  ..:|..:|.|.::.  .|.|.|||.::....|...:   ..|....|:
Worm   422 AVDTQLYLVAPIVLV--ALYFSFAAGTAIIVAGCVGSIITTYILFGVYNVPADIIGNGDQTKFFN 484

  Fly   672 KIYDKPWTRLGPYLIGMAVGWILFRTNC-KIRLPKLTVATAWTLAMLNLFVLVFGLYKAD----L 731
            ..|.|||.|..|||:|:..|::|..... ||||........|..|.:.....:|..|..|    .
Worm   485 IAYSKPWIRCPPYLVGLLTGYLLATYGSRKIRLNWALAIAGWITAFVIAGFCLFATYDYDKGAHW 549

  Fly   732 SQFTAAAYSSLSHSAWALSLAWITIACSTGYGGYINSLLSAPCLYPFSRVTYCAYLVHPIVIRSM 796
            |.||.|.:.:.....|.:.:.|:..|...|:||.|:..:|.|...||.|::||||:||.:|: ..
Worm   550 STFTRATFYNFHRLGWGVFVCWVVGANHMGWGGPIDKFMSHPIWQPFGRLSYCAYIVHWMVL-YY 613

  Fly   797 ALNSDAPLHLGGDLMVVMFFGL--TVASYFLSFVVSMSFEAPVVTMLKIL 844
            .||....||......|..:..:  |:.||.|:|..|..||.|::.:.|:|
Worm   614 YLNVGGVLHYSSAWQVFTYIAIPATLLSYVLAFFWSCLFEVPILKLEKML 663

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32645	NP_727670.1	NRF	121..272	CDD:214781	33/171 (19%)
		Acyl_transf_3	445..831	CDD:280013	121/408 (30%)
		OafA	450..853	CDD:224748	125/418 (30%)
oac-32	NP_001300114.1	NRF	77..185	CDD:214781	31/155 (20%)
oac-32	NP_001300114.1	OafA	254..659	CDD:224748	126/426 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	204	1.000	Domainoid score	I1719
eggNOG	1	0.900	-	-		E1_KOG3700
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7984
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100705
Panther	1	1.100	-	-	O	PTHR11161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X299
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.770