DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32645 and ndg-4

DIOPT Version :9

Sequence 1:	NP_727670.1	Gene:	CG32645 / 32264	FlyBaseID:	FBgn0052645	Length:	853	Species:	Drosophila melanogaster
Sequence 2:	NP_001022618.1	Gene:	ndg-4 / 175582	WormBaseID:	WBGene00003577	Length:	687	Species:	Caenorhabditis elegans

Alignment Length:	903	Identity:	175/903 - (19%)
Similarity:	302/903 - (33%)	Gaps:	280/903 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 RTLVLAMLLSLLA---------TPQAAIDKDDGKFPP--GRH-NLSSAPDQHNVINLSLHGDLTA 56
            ||.::.:.|..||         ||......|..|.|.  |:: :|...|...|           |
Worm     2 RTFLITLALCQLALSCTLCHFRTPPRPRPLDQYKLPKLGGKNLDLEKMPKFCN-----------A 55

  Fly    57 ATLLPHVDP-KLSYDLSQTRRLRDALNVFDLAVLAAQWGQVESSGGVS--ANCSRDMRSYLGGLS 118
            :..||.:|. |..::           .:|   ..|.:|  .::.||..  ||.|...:......:
Worm    56 SKELPVMDSCKKQFE-----------KIF---CSADRW--TDTFGGCQSIANKSLSEQEQCSKCA 104

  Fly   119 DAKM---WAVKMDDASGHYTSGFFYGNNYWMGSLALCDAID-----DGQIVAPGKDNSSSAASSP 175
            ..|.   |.:|..|:.|...:|...||.||:|...||.|:.     |||.            ...
Worm   105 YQKANNGWVLKWFDSLGKPAAGITDGNYYWLGDYELCAALASDGSFDGQY------------CRI 157

  Fly   176 ESETKNSGLPFAAAHTQGYSSVYNAPPPFVPGFYVIKMQLNETLPTQVLRIIYVGMCLPSSCSIA 240
            |.|..::|:......|...|                               |.:|:|.||:||:|
Worm   158 EMEVPDAGVESGCPQTDPLS-------------------------------IILGVCFPSACSVA 191

  Fly   241 DIGQMSSRAHVELPSRDLRVLDIRVPTDKEFNIWADKTFCLLIVVSSIVLGLICCGTLFEIYLRR 305
            |:..:||   :.||      .:::|..:.: |.|:..|..|||::...::
Worm   192 DLTTVSS---IYLP------YNLKVECESQ-NRWSFVTVLLLIILMVWIV--------------- 231

  Fly   306 KLKEALRRQDKEMMNNSETSSGIGCASSDYSDTMTAHDDPLKQSDHSQSSNSLKQLDALVLNLPP 370
                      .:.:...:|||
Worm   232 ----------PQAVATFQTSS-------------------------------------------- 242

  Fly   371 NDNDSGNGHHHDHDAEHDHHDHHRSGSNNSNSDEHLEGHLHEPEKLSIYSELLLSFSAITNFNAI 435
              |||                                              :|..||...|....
Worm   243 --NDS----------------------------------------------ILSCFSIPDNAKRT 259

  Fly   436 CDRNVGADTIPCIHGLRAFSMAWVILGHTCIVVFKYSDNMEMRKEVEQNFFFQAITNGPFSVDTF 500
            ......:..:..:|||.......::.|.....:..|.:|:....|...:|....:.|..:.:|..
Worm   260 FSTRRESPNLHVVHGLEFLLFFTIVSGMVYNFMLPYIENVAFAFEGVSSFPMHIVNNYSYQIDGL 324

  Fly   501 FFISGFLISYIYFRTNAKGKLNKLSKGANEFTAGTAHFFGLVAYRFMRLTAPYLFVLGVVQVTMK 565
            ..:|.|..:|:.|              .|..|..:|  |..:..|..|....|     :|.|...
Worm   325 LALSAFYTTYLLF--------------GNILTLRSA--FDYILMRLFRFWPAY-----IVCVLFM 368

  Fly   566 YLATYSIFDPPTMDHI----TCPDYWWRNILYINTLFPVDEMCMLWSWYLANDTQFYMIGAIILI 626
            |:....:...|...|.    .|...||:|||:||..|.|.:.|:...:.::.:.|:|.|...::.
Worm   369 YVIFPGVSSGPMWIHTDTVNRCGSGWWKNILFINNWFNVTDTCVDIGYVISMEAQYYAILIFVIF 433

  Fly   627 VGVRHFKLSAITTLVFLVLSWITTAVIAFTNNHRPN---TDDPL------ALFDKIYDKPWTRLG 682
            :..::..|:.:........|.|.:.|.|::....|.   |.:|:      |:||::....:.|..
Worm   434 LSSKYPLLTQLFAYTVFGSSIIFSFVRAYSQELPPAPMLTLEPVPLTKVYAVFDQLLLSLFARSS 498

  Fly   683 PYLIGMAVGWILFRTNCKIRLPKLTVATAWTLAMLNL-FVLV-------FGLYKADLSQFTA--A 737
            .|.:|...|......:.::|...|:......||::.: |.:|       :..| |.:|.|..  |
Worm   499 NYCLGFIFGIGCATASDELRESGLSYCMHKLLAIICIAFAVVPFVGAFPYSAY-AWVSNFEIMNA 562

  Fly   738 AYSSLSHSAWALSLAWITIACSTGYGG--YINSLLSAPCLYPFSRVTYCAYLV-HPIVIRSM-AL 798
            :|::|....|:.:|......|..|...  ::|:||......|.|:||:.|.:| .||::... :|
Worm   563 SYAALHRPMWSFALLSFVYLCHHGAFSKEWLNALLEWRVFAPLSKVTWIALVVAEPIILYFFSSL 627

  Fly   799 NSDA-PLHLGGDLMVVMFFGLTVA--SYFLSFVVSMSFEAPVVTMLKILSPSRKKRLA 853
            |..| ..|..     .|:..::.|  :||::..:.:....|:   ..::.|.:|.|.|
Worm   628 NKPAYATHWS-----TMYTAISTALLAYFVAMFLDIFVTRPI---RYLIYPEQKHRYA 677

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32645	NP_727670.1	NRF	121..272	CDD:214781	36/158 (23%)
		Acyl_transf_3	445..831	CDD:280013	91/415 (22%)
		OafA	450..853	CDD:224748	94/432 (22%)
ndg-4	NP_001022618.1	NRF	110..215	CDD:214781	36/157 (23%)
ndg-4	NP_001022618.1	OafA	325..668	CDD:224748	82/372 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1171418at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920