Protein Alignment MFS10 and Slc17a6

DIOPT Version :10

• Sequence 1: NP_572857.1
• Gene: MFS10 / 32263
• FlyBaseID: FBgn0030452
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_445879.1
• Gene: Slc17a6 / 84487
• RGDID: 620531
• Length: 582
• Species: Rattus norvegicus
• Alignment Length: 492
• Identity: 158/492 - (32%)
• Similarity: 258/492 - (52%)
• Gaps: 42/492 - (8%)

  Fly    64 GPKTRHIFGFMGFLGFAVVYAMRVNLSVAIVAMVNQTAIPHSNSSVIDTDTCPLPAPHHNGSDPN 128
            |...|:|...|..|||.:.:.:|.||.||||.|||.:.| |....||
  Rat    66 GLPRRYIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTI-HRGGKVI------------------ 111

  Fly   129 PQKEGEFVWDEATQGLVLGSFFYGYVLTQVPGGRMAELYGGKKIYGYGVLITAVFTLITPLAAHW 193
             :::.:|.||..|.|::.||||:||::||:|||.:|......:::|..:|:|:...::.|.||..
  Rat   112 -KEKAKFNWDPETVGMIHGSFFWGYIITQIPGGYIASRLAANRVFGAAILLTSTLNMLIPSAARV 175

  Fly   194 DLPLLVLVRILEGMGEGVTYPAMHAMLAHWIPPLERNKFAAIVYAGSNIGTVISMPLAGWLCSLD 258
            ....::.||||:|:.|||||||.|.:.:.|.|||||::.|...:.||..|.||:|||||.|....
  Rat   176 HYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYT 240

  Fly   259 FLGGWPSAFYIFGLLGILWFIAWMYLVYDKPSDHPRISESEREYIERSLQVQRLINQDLAEAEEE 323
               ||.|.||::|..|::|::.|:.:.|:.|:.||.|::.||.|||.|:
  Rat   241 ---GWSSVFYVYGSFGMVWYMFWLLVSYESPAKHPTITDEERRYIEESI---------------- 286

  Fly   324 EGQDEVSLRAPPEEPIPWSSLLTSVPLWAILLTQCGQGWAFYTQLTELPTYMSNILHFDIQSNAL 388
             |:....|.|..:...||....||:|::||::....:.|.||..|...|.|...:..|:|....:
  Rat   287 -GESANLLGAMEKFKTPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGM 350

  Fly   389 LNAVPYLTSWFVGIACSALADWMLARRYISLLNSYKLWNTVASVVPSLGLIGIIYVGCDWVWVTF 453
            |:|||:|....:......:||::.:::.:|.....|:.|.....:.:..|:.:.|.....|.::|
  Rat   351 LSAVPHLVMTIIVPIGGQIADFLRSKQILSTTTVRKIMNCGGFGMEATLLLVVGYSHTRGVAISF 415

  Fly   454 MLAGVGSFGGAVYAGNQMNHIALSPRYAGTMYGITNSAANICGFLAPYVIGLIINHRETLTQWHL 518
            ::..|| |.|...:|..:||:.::||||..:.||:|....:.|.:.|.::|.:..:: :..:|..
  Rat   416 LVLAVG-FSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTKNK-SREEWQY 478

  Fly   519 VFWLAAGLNIAGNFIYLIFASAEEQSWSKTPPTRNSR 555
            ||.:||.::..|...|.:|||.|:|.|:....|...:
  Rat   479 VFLIAALVHYGGVIFYALFASGEKQPWADPEETSEEK 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS10	NP_572857.1	MFS_SLC17	73..538	CDD:340876	148/464 (32%)
Slc17a6	NP_445879.1	MFS_SLC17A6_7_8_VGluT	74..498	CDD:340940	148/465 (32%)