Protein Alignment MFS10 and SLC37A3

DIOPT Version :10

• Sequence 1: NP_572857.1
• Gene: MFS10 / 32263
• FlyBaseID: FBgn0030452
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_996996.1
• Gene: SLC37A3 / 84255
• HGNCID: 20651
• Length: 494
• Species: Homo sapiens
• Alignment Length: 485
• Identity: 99/485 - (20%)
• Similarity: 179/485 - (36%)
• Gaps: 117/485 - (24%)

  Fly    52 RSSGAAEENHGCGPKTRHIFGF-MGFLGFAVVYAMRVNLSVAIVAMVNQTAIPHSNSSVIDTDTC 115
            |.|..::.:|      .|:..| :.|..:::::|.|...|...|::..|......|:||    ..
Human     9 RGSLLSQFSH------HHVVVFLLTFFSYSLLHASRKTFSNVKVSISEQWTPSAFNTSV----EL 63

  Fly   116 PLPAPHHNGSDPNPQKEGEFVWDEATQGLVLGSFFYGYVLTQVPGGRMAELYGGKKIYGYGV--- 177
            |:.....|...|:.:|...|:....|  :.|.|:..|..::.:.|.|:    ..:.:..:|:
Human    64 PVEIWSSNHLFPSAEKATLFLGTLDT--IFLFSYAVGLFISGIVGDRL----NLRWVLSFGMCSS 122

  Fly   178 -LITAVFTLITPLAAHWDLPLLVLVRILEGMGEGVTYPAMHAMLAHWIPPLERNKFAAIVYAGSN 241
             |:..||..:|.....::..|...:.|:.|:.:...:|.:.|::.:|.....|.....:..|.::
Human   123 ALVVFVFGALTEWLRFYNKWLYCCLWIVNGLLQSTGWPCVVAVMGNWFGKAGRGVVFGLWSACAS 187

  Fly   242 IGTVISMPLAGWL------------CSLDFLGGWPSAFYIFGLL------GILWFIAWMYLVYDK 288
            :|.::...||..:            .|:.|.||   ....||||      |:....|...  :::
Human   188 VGNILGACLASSVLQYGYEYAFLVTASVQFAGG---IVIFFGLLVSPEEIGLSGIEAEEN--FEE 247

  Fly   289 PSDHPRIS--ESEREYIERSLQVQRLINQDLAEAEEEEGQDEVSLRAPPEEPIPWSSLLTSVPL- 350
            .|..|.|:  |:|.|| |.:..:|.  :..:|:.:.........|..    .||:|.....:.|
Human   248 DSHRPLINGGENEDEY-EPNYSIQD--DSSVAQVKAISFYQACCLPG----VIPYSLAYACLKLV 305

  Fly   351 ------WAILLTQCGQGW--AFYTQLT-----------ELPTYMSNILH---------------- 380
                  |.........||  |...:|:           .|..::|::|.
Human   306 NYSFFFWLPFYLSNNFGWKEAEADKLSIWYDVGGIIGGTLQGFISDVLQKRAPVLALSLLLAVGS 370

  Fly   381 --------FDIQSNALLNAVPYLTSWFVG-----IACSALADWMLARRYISLLNSYKLWNTVASV 432
                    .|...||||..|   |.:|:|     |:.:..||  |.|:.: :..|.:...||..:
Human   371 LIGYSRSPNDKSINALLMTV---TGFFIGGPSNMISSAISAD--LGRQEL-IQRSSEALATVTGI 429

  Fly   433 VPSLGLIG---------IIYVGCDWVWVTF 453
            |...|.||         :|.....|:||.:
Human   430 VDGSGSIGAAVGQYLVSLIRDKLGWMWVFY 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS10	NP_572857.1	MFS_SLC17	73..538	CDD:340876	95/464 (20%)
SLC37A3	NP_996996.1	MFS_SLC37A3	20..476	CDD:340900	96/468 (21%)