DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS10 and PHT4;1

DIOPT Version :9

Sequence 1:	NP_001285188.1	Gene:	MFS10 / 32263	FlyBaseID:	FBgn0030452	Length:	559	Species:	Drosophila melanogaster
Sequence 2:	NP_180526.1	Gene:	PHT4;1 / 817515	AraportID:	AT2G29650	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	564	Identity:	160/564 - (28%)
Similarity:	262/564 - (46%)	Gaps:	98/564 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PPHKWTDESR----------DASCYYDPSTSSNSSASAERSDDEADDEREAF-----CSGERPLI 51
            ||.| |..||          ....:..|...|:......||.|:::.....:     .||...::
plant    21 PPEK-TSSSRSLRNLKPSPKSLRVWIYPRNRSSVFRVLVRSSDKSESSNSYYVEGDKVSGNNDVV 84

  Fly    52 RSSGAA------EENHGCGPKTRHIFGFMGFLGFAVVYAMRVNLSVAIVAMVNQTAIPHSNSSVI 110
            ..|.::      ||    .|| |.:...:.|..|.:....|||:|:||:.|
plant    85 SDSPSSIVLPWWEE----FPK-RWVIVLLCFSAFLLCNMDRVNMSIAILPM-------------- 130

  Fly   111 DTDTCPLPAPHHNGSDPNPQKEGEFVWDEATQGLVLGSFFYGYVLTQVPGGRMAELYGGKKIYGY 175
                                 ..|:.|:.||.||:..|||:||:|||:.||..|:..|||::.|:
plant   131 ---------------------SAEYGWNPATVGLIQSSFFWGYLLTQIAGGIWADTVGGKRVLGF 174

  Fly   176 GVLITAVFTLITPLAAHWDLPLLVLVRILEGMGEGVTYPAMHAMLAHWIPPLERNKFAAIVYAGS 240
            ||:..::.|::||:||...||.|::||...|:||||..|||:.:|:.|:|..||::..|:||:|.
plant   175 GVIWWSIATILTPVAAKLGLPYLLVVRAFMGVGEGVAMPAMNNILSKWVPVQERSRSLALVYSGM 239

  Fly   241 NIGTVISMPLAGWLCSLDFLGGWPSAFYIFGLLGILWFIAWMYLVYDKPSDHPRISESEREYIER 305
            .:|:|..:..:.:|.. .|  ||||.||.||.||.:|...|:......|.:.|.:...||
plant   240 YLGSVTGLAFSPFLIH-QF--GWPSVFYSFGSLGTVWLTLWLTKAESSPLEDPTLLPEER----- 296

  Fly   306 SLQVQRLINQDLAEAEEEEGQDEVSLRAPPEEPIPWSSLLTSVPLWAILLTQCGQGWAFYTQLTE 370
                 :||..:.|..|             |.:.|||..:|:..|:||::.......|..:..||.
plant   297 -----KLIADNCASKE-------------PVKSIPWRLILSKPPVWALISCHFCHNWGTFILLTW 343

  Fly   371 LPTYMSNILHFDIQSNALLNAVPYLTSWFVGIACSALADWMLARRYISLLNSYKLWNTVASVVPS 435
            :|||...:|.|::..:.||:..|::|......|...:||.:::|.: |:.|..|:..|:..:.|:
plant   344 MPTYYHQVLKFNLMESGLLSVFPWMTMAISANAGGWIADTLVSRGF-SVTNVRKIMQTIGFLGPA 407

  Fly   436 LGLIGIIYVGCDWVWVTFMLA--GVGSFGGAVYAGNQMNHIALSPRYAGTMYGITNSAANICGFL 498
            ..|..:.::....:.|..|..  |..:|.   .:|...||..::|||:|.:.|::|:|..:.|.|
plant   408 FFLTQLKHIDSPTMAVLCMACSQGTDAFS---QSGLYSNHQDIAPRYSGVLLGLSNTAGVLAGVL 469

  Fly   499 APYVIGLIINHRETLTQWHLVFWLAAGLNIAGNFIYLIFASAEE 542
            .....|.|:.|    ..|..||.::.||.:.|..|:.:|::.|:
plant   470 GTAATGHILQH----GSWDDVFTISVGLYLVGTVIWNLFSTGEK 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS10	NP_001285188.1	2A0114euk	63..547	CDD:129972	144/482 (30%)
MFS10	NP_001285188.1	MFS	134..538	CDD:119392	130/405 (32%)
PHT4;1	NP_180526.1	MFS_SLC17A9_like	106..505	CDD:340938	139/467 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm8397
orthoMCL	1	0.900	-	-		OOG6_100421
Panther	1	1.100	-	-	LDO	PTHR11662
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.810