Protein Alignment MFS10 and SLC17A6

DIOPT Version :9

• Sequence 1: NP_001285188.1
• Gene: MFS10 / 32263
• FlyBaseID: FBgn0030452
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_065079.1
• Gene: SLC17A6 / 57084
• HGNCID: 16703
• Length: 582
• Species: Homo sapiens
• Alignment Length: 492
• Identity: 159/492 - (32%)
• Similarity: 258/492 - (52%)
• Gaps: 42/492 - (8%)

  Fly    64 GPKTRHIFGFMGFLGFAVVYAMRVNLSVAIVAMVNQTAIPHSNSSVIDTDTCPLPAPHHNGSDPN 128
            |...|:|...|..|||.:.:.:|.||.||||.|||.:.| |....||
Human    66 GLPRRYIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTI-HRGGKVI------------------ 111

  Fly   129 PQKEGEFVWDEATQGLVLGSFFYGYVLTQVPGGRMAELYGGKKIYGYGVLITAVFTLITPLAAHW 193
             :::.:|.||..|.|::.||||:||::||:|||.:|......:::|..:|:|:...::.|.||..
Human   112 -KEKAKFNWDPETVGMIHGSFFWGYIITQIPGGYIASRLAANRVFGAAILLTSTLNMLIPSAARV 175

  Fly   194 DLPLLVLVRILEGMGEGVTYPAMHAMLAHWIPPLERNKFAAIVYAGSNIGTVISMPLAGWLCSLD 258
            ....::.||||:|:.|||||||.|.:.:.|.|||||::.|...:.||..|.||:|||||.|....
Human   176 HYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYT 240

  Fly   259 FLGGWPSAFYIFGLLGILWFIAWMYLVYDKPSDHPRISESEREYIERSLQVQRLINQDLAEAEEE 323
               ||.|.||::|..|::|::.|:.:.|:.|:.||.|::.||.|||.|:
Human   241 ---GWSSVFYVYGSFGMVWYMFWLLVSYESPAKHPTITDEERRYIEESI---------------- 286

  Fly   324 EGQDEVSLRAPPEEPIPWSSLLTSVPLWAILLTQCGQGWAFYTQLTELPTYMSNILHFDIQSNAL 388
             |:....|.|..:...||....||:|::||::....:.|.||..|...|.|...:..|:|....:
Human   287 -GESANLLGAMEKFKTPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGM 350

  Fly   389 LNAVPYLTSWFVGIACSALADWMLARRYISLLNSYKLWNTVASVVPSLGLIGIIYVGCDWVWVTF 453
            |:|||:|....:......:||::.:::.:|.....|:.|.....:.:..|:.:.|.....|.::|
Human   351 LSAVPHLVMTIIVPIGGQIADFLRSKQILSTTTVRKIMNCGGFGMEATLLLVVGYSHTRGVAISF 415

  Fly   454 MLAGVGSFGGAVYAGNQMNHIALSPRYAGTMYGITNSAANICGFLAPYVIGLIINHRETLTQWHL 518
            ::..|| |.|...:|..:||:.::||||..:.||:|....:.|.:.|.::|.:..:: :..:|..
Human   416 LVLAVG-FSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTKNK-SREEWQY 478

  Fly   519 VFWLAAGLNIAGNFIYLIFASAEEQSWSKTPPTRNSR 555
            ||.:||.::..|...|.||||.|:|.|:....|...:
Human   479 VFLIAALVHYGGVIFYAIFASGEKQPWADPEETSEEK 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS10	NP_001285188.1	2A0114euk	63..547	CDD:129972	158/482 (33%)
		MFS	134..538	CDD:119392	131/403 (33%)
SLC17A6	NP_065079.1	MFS_SLC17A6_7_8_VGluT	74..498	CDD:340940	149/465 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100421
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.710