Protein Alignment MFS10 and SLC17A7

DIOPT Version :10

• Sequence 1: NP_572857.1
• Gene: MFS10 / 32263
• FlyBaseID: FBgn0030452
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_064705.1
• Gene: SLC17A7 / 57030
• HGNCID: 16704
• Length: 560
• Species: Homo sapiens
• Alignment Length: 484
• Identity: 161/484 - (33%)
• Similarity: 258/484 - (53%)
• Gaps: 42/484 - (8%)

  Fly    64 GPKTRHIFGFMGFLGFAVVYAMRVNLSVAIVAMVNQTAIPHSNSSVIDTDTCPLPAPHHNGSDPN 128
            |...|:|...|..|||.:.:.:|.||.||||:|||       ||:.            |.|....
Human    58 GLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVN-------NSTT------------HRGGHVV 103

  Fly   129 PQKEGEFVWDEATQGLVLGSFFYGYVLTQVPGGRMAELYGGKKIYGYGVLITAVFTLITPLAAHW 193
            .|| .:|.||..|.||:.||||:||::||:|||.:.:.:...:::|:.::.|:...::.|.||..
Human   104 VQK-AQFSWDPETVGLIHGSFFWGYIVTQIPGGFICQKFAANRVFGFAIVATSTLNMLIPSAARV 167

  Fly   194 DLPLLVLVRILEGMGEGVTYPAMHAMLAHWIPPLERNKFAAIVYAGSNIGTVISMPLAGWLCSLD 258
            ....::.||||:|:.|||||||.|.:.:.|.|||||::.|...:.||..|.|::|||||.|..
Human   168 HYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTAFCGSYAGAVVAMPLAGVLVQ-- 230

  Fly   259 FLGGWPSAFYIFGLLGILWFIAWMYLVYDKPSDHPRISESEREYIERSLQVQRLINQDLAEAEEE 323
             ..||.|.||::|..||.|::.|:.:.|:.|:.||.|||.||:|||.::
Human   231 -YSGWSSVFYVYGSFGIFWYLFWLLVSYESPALHPSISEEERKYIEDAI---------------- 278

  Fly   324 EGQDEVSLRAPPEEPIPWSSLLTSVPLWAILLTQCGQGWAFYTQLTELPTYMSNILHFDIQSNAL 388
             |:....:....:...||....||:|::||::....:.|.||..|...|.|...:..|:|....|
Human   279 -GESAKLMNPLTKFSTPWRRFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGL 342

  Fly   389 LNAVPYLTSWFVGIACSALADWMLARRYISLLNSYKLWNTVASVVPSLGLIGIIYVGCDWVWVTF 453
            ::|:|:|....:......:||::.:||.:|..|..||.|.....:.:..|:.:.|.....|.::|
Human   343 VSALPHLVMTIIVPIGGQIADFLRSRRIMSTTNVRKLMNCGGFGMEATLLLVVGYSHSKGVAISF 407

  Fly   454 MLAGVGSFGGAVYAGNQMNHIALSPRYAGTMYGITNSAANICGFLAPYVIGLIINHRETLTQWHL 518
            ::..|| |.|...:|..:||:.::||||..:.||:|....:.|.:.|.::|.:..|: |..:|..
Human   408 LVLAVG-FSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPIIVGAMTKHK-TREEWQY 470

  Fly   519 VFWLAAGLNIAGNFIYLIFASAEEQSWSK 547
            ||.:|:.::..|...|.:|||.|:|.|::
Human   471 VFLIASLVHYGGVIFYGVFASGEKQPWAE 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS10	NP_572857.1	MFS_SLC17	73..538	CDD:340876	152/464 (33%)
SLC17A7	NP_064705.1	MFS_SLC17A6_7_8_VGluT	66..490	CDD:340940	152/465 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	497..560		1/3 (33%)