Protein Alignment MFS10 and SLC37A1

DIOPT Version :10

• Sequence 1: NP_572857.1
• Gene: MFS10 / 32263
• FlyBaseID: FBgn0030452
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: XP_054180549.1
• Gene: SLC37A1 / 54020
• HGNCID: 11024
• Length: 637
• Species: Homo sapiens
• Alignment Length: 535
• Identity: 101/535 - (18%)
• Similarity: 206/535 - (38%)
• Gaps: 148/535 - (27%)

  Fly   119 APHHNGSDPNPQKEGEFVW---DEATQGLVLGSFFYGYVLTQVPGGRMAELYGGK---KIY-GYG 176
            |||.     .|..|.:..|   |:.....:||:..|.::.....|..::.:.|.:   :.| .:|
Human    74 APHQ-----LPDNETDCGWAPFDKNNYQQLLGALDYSFLCAYAVGMYLSGIIGERLPIRYYLTFG 133

  Fly   177 VLITAVFTLITPLAAHWDL---PLLVLVRILEGMGEGVTYPAMHAMLAHWIPPLERNKFAAIVYA 238
            :|.:..||.:..|...:::   ...|:.:::.|:.:...:|::...|.:|.....|.....:..:
Human   134 MLASGAFTALFGLGYFYNIHSFGFYVVTQVINGLVQTTGWPSVVTCLGNWFGKGRRGLIMGVWNS 198

  Fly   239 GSNIGTVISMPLAG-WLCSLDFLGGWPSAFYIFG-LLGILWFIAWMYLVYDKPSD---------H 292
            .:::|.::...:|| |:.:.     |..:|.:.| ::..:..:.:::|: :.|:|         |
Human   199 HTSVGNILGSLIAGYWVSTC-----WGLSFVVPGAIVAAMGIVCFLFLI-EHPNDVRCSSTLVTH 257

  Fly   293 PRISE--SEREYIERSL-----------QVQRLINQD-----------LAEAEEEEGQDEVSLRA 333
            .:..|  :.|..:::.:           ::|.|:..|           :...:...|...:|...
Human   258 SKGYENGTNRLRLQKQILKSEKNKPLDPEMQCLLLSDGKGSIHPNHVVILPGDGGSGTAAISFTG 322

  Fly   334 PPEEP--IPWSSLLTSVPLWAILLTQCGQGWAFYTQLTELPTYMSNILHFDIQSNALLNAVPYLT 396
            ..:.|  |.:|..|    |:|.|::        ||.|..||.|::|:.|.|.:....|:.:..:.
Human   323 ALKIPGVIEFSLCL----LFAKLVS--------YTFLFWLPLYITNVDHLDAKKAGELSTLFDVG 375

  Fly   397 SWFVGIACSALADWMLARR--------------YI-SLLNSYKLWNTVASVVPSLGLIGIIYVGC 446
            ..|.||....::|.:..|.              || |.::...|..|:|.::    |.|.:..|.
Human   376 GIFGGILAGVISDRLEKRASTCGLMLLLAAPTLYIFSTISKMGLEATIAMLL----LSGALVSGP 436

  Fly   447 DWVWVTFMLAGVGSFGGAVYAGNQMNHIALSPRYAGTMYGITNSAANICGFLAPYVIGLIINHRE 511
            ..:..|.:.|.:|:     :...:.|..|||     |:..|.:...::...|.|.:.||:
Human   437 YTLITTAVSADLGT-----HKSLKGNAHALS-----TVTAIIDGTGSVGAALGPLLAGLL----- 486

  Fly   512 TLTQWHLVFWLAAGLNIAGNFIYLIFASA-------EEQSW------------SKTP-------- 549
            :.:.|..||::            |:||.|       :..||            |.:|
Human   487 SPSGWSNVFYM------------LMFADACALLPCFQGSSWFFVGLHQTALPSSDSPALIRQPCP 539

  Fly   550 -----PTRNSRSQRA 559
                 ||.:|.:.|:
Human   540 HQTALPTSDSPAHRS 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS10	NP_572857.1	MFS_SLC17	73..538	CDD:340876	90/480 (19%)
SLC37A1	XP_054180549.1	MFS_SLC37A1_2	21..507	CDD:340902	93/486 (19%)