DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS10 and MFS18

DIOPT Version :9

Sequence 1:	NP_001285188.1	Gene:	MFS10 / 32263	FlyBaseID:	FBgn0030452	Length:	559	Species:	Drosophila melanogaster
Sequence 2:	NP_608835.1	Gene:	MFS18 / 33650	FlyBaseID:	FBgn0025684	Length:	439	Species:	Drosophila melanogaster

Alignment Length:	473	Identity:	129/473 - (27%)
Similarity:	218/473 - (46%)	Gaps:	86/473 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 VAIVAMVNQTAIPHSNSSVIDTDTCPLPAPHHNGSDPNPQKEGEFVWDEATQGLVLGSFFYGYVL 155
            |..:.::..|.:.:|..:     |.||..|    :..:.||     |.:...|.||.|||:||.|
  Fly    28 VWFITLITGTCMLYSTRT-----TMPLLVP----AVASAQK-----WSKTDSGTVLSSFFWGYTL 78

  Fly   156 TQVPGGRMAELYGGKKIYGYGVLITAVFTLITPLAAHWD--------LPLLVLVRILEGMGEGVT 212
            |||.||..::.:||:::..:..:..::.|.:.|... |.        :|.:|.:|||.|..:||.
  Fly    79 TQVVGGYFSDRFGGQRVILFAAIGWSLITFLMPTII-WTAGSIKSYAIPFIVAIRILNGALQGVH 142

  Fly   213 YPAMHAMLAHWIPPLERNKFAAIVYAGSNIGTVISMPLAGWLCSLDFLGGWPSAFYIFGLLGILW 277
            :|:|.::.:..:.|.||:.|..::.|||.:||:::..:..:|  ||:. ||...|.:.||:||.|
  Fly   143 FPSMISLTSQNLCPNERSSFFGLLTAGSALGTLLTGIMGSFL--LDYF-GWSYVFRVIGLMGIAW 204

  Fly   278 FIAWMYLVYDKPSDHPRISESEREYIERSLQVQRLINQDLAEAEEEEGQDEVSLRAPPEEPIPWS 342
            .:...|  |....:..||       |..:...:...|:..||.                ..:||.
  Fly   205 ALVLRY--YAMAGERNRI-------INIATPSRLCANKSPAET----------------SAVPWL 244

  Fly   343 SLLTSVPLWAILLTQCGQGWAFYTQLTELPTYMSNILHFDIQSNALLNAVPYLTSWFVGIACSAL 407
            .....:..||.:||...:...|:..|:.||||..:  .|......::|.:|:|          ||
  Fly   245 RYFRRLSFWACVLTHACEMNCFFVLLSWLPTYFHD--GFPHAKGWVVNMIPWL----------AL 297

  Fly   408 ADWMLARRYISLLNSYKLWN--TVASVVPS-------LGLIGIIYVGCDW----VWVTFMLAGVG 459
            ....|..:|::.....:.|:  ||..|:.|       |.|. ::....|:    :.:|.::.|.|
  Fly   298 PPCTLFAKYLTTRLLAREWHTTTVRKVIQSCCFAAQNLALF-VMSRTSDFHTALICMTIIIGGTG 361

  Fly   460 SFGGAVYAGNQMNHIALSPRYAGTMYGITNSAANICGFLAPYVIGLIINHRETLTQ-WHLVFWLA 523
            ....||    .:|...|:|.::|:::|:.|:...|.|||..|:.|.|:.    ||| |.:||..|
  Fly   362 FHNNAV----TVNPQDLAPLHSGSVFGLMNTVGAIPGFLGVYLAGHILE----LTQSWPMVFSAA 418

  Fly   524 AGLNIAGNFIYLIFASAE 541
            ||:|:.|..|:::|.|||
  Fly   419 AGINLVGWIIFIVFGSAE 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS10	NP_001285188.1	2A0114euk	63..547	CDD:129972	129/473 (27%)
MFS10	NP_001285188.1	MFS	134..538	CDD:119392	116/425 (27%)
MFS18	NP_608835.1	MFS	30..432	CDD:119392	124/465 (27%)
MFS18	NP_608835.1	MFS_1	32..397	CDD:284993	108/424 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.960