DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS10 and CG6978

DIOPT Version :9

Sequence 1:	NP_001285188.1	Gene:	MFS10 / 32263	FlyBaseID:	FBgn0030452	Length:	559	Species:	Drosophila melanogaster
Sequence 2:	NP_572188.1	Gene:	CG6978 / 31413	FlyBaseID:	FBgn0029727	Length:	479	Species:	Drosophila melanogaster

Alignment Length:	538	Identity:	199/538 - (36%)
Similarity:	291/538 - (54%)	Gaps:	65/538 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 DASCYYDPSTSSNSSASAERSDDEADDEREAFCSGERPLIRSSGAAEENHGCGPKTRHIFGFMGF 76
            |.:..||....||.:    |||.|...||.| ..|:.|..|             |||.....|.|
  Fly     3 DTAGVYDSKGVSNRN----RSDQEVRMERYA-SDGQIPRCR-------------KTRFFVVLMLF 49

  Fly    77 LGFAVVYAMRVNLSVAIVAMVNQTAIPHSNSSVIDTDTCPLPAPHHNGSDPNPQKEGEFVWDEAT 141
            .|.|..|.||.|:|||||||||.|||.|:.||.                 .:.:::|:|.|....
  Fly    50 SGMANAYVMRTNMSVAIVAMVNHTAISHTKSST-----------------QSKERDGDFEWSYKL 97

  Fly   142 QGLVLGSFFYGYVLTQVPGGRMAELYGGKKIYGYGVLITAVFTLITPLAAH-WDLPLLVLVRILE 205
            ||.:|.|||||||:||:|.|.|.:.||.:...|:|::|.::.....|::|. ..:..|.:||.::
  Fly    98 QGYILSSFFYGYVITQIPFGLMIKYYGARHFLGWGMMINSLAAFFIPISARSGGVVGLCVVRFIQ 162

  Fly   206 GMGEGVTYPAMHAMLAHWIPPLERNKFAAIVYAGSNIGTVISMPLAGWLCSLDFLGGWPSAFYIF 270
            |:|||...|..|::||.|:||.||:...|.||||:..||::||||:|.|....|.|||||.||||
  Fly   163 GLGEGPIVPCSHSLLAQWVPPNERSLAGAAVYAGAQFGTIVSMPLSGLLAHYGFDGGWPSIFYIF 227

  Fly   271 GLLGILWFIAWMYLVYDKPSDHPRISESEREYIERSLQVQRLINQDLAEAEEEEGQDEVSLRAPP 335
            ||...:|.|.::.||.:.|:...||||:||.:|.                       |...:|.|
  Fly   228 GLFSTIWCIIFICLVQESPAVSTRISEAERRHIM-----------------------EAIWQAQP 269

  Fly   336 EE--PIPWSSLLTSVPLWAILLTQCGQGWAFYTQLTELPTYMSNILHFDIQSNALLNAVPYLTSW 398
            ||  .||:..:..|.|.:|||:...|..:.:.|.:|.|||||..:|:.:|::|.:::::|||..|
  Fly   270 EERSRIPFLGIAKSPPFYAILVAHAGHNYGYETLMTMLPTYMYRVLNVNIRTNGIISSLPYLAMW 334

  Fly   399 FVGIACSALADWMLARRYISLLNSYKLWNTVASVVPSLGLIGIIYVGCD-WVWVTFMLAGVGSFG 462
            .:.|....||| .|.||..|:....||.|::....|::.||.:.:|... |:.....:.|:| ..
  Fly   335 ILAIVFGILAD-CLIRRNFSITVVRKLMNSLGQYGPAVALISVGFVHHSLWLTSVIFILGMG-LN 397

  Fly   463 GAVYAGNQMNHIALSPRYAGTMYGITNSAANICGFLAPYVIGLIINHRETLTQWHLVFWLAAGLN 527
            ||:|.|.::||:.||||:||.:..:||..||:.|.:||.|.|.:|:.:.::..|.:||::|||:.
  Fly   398 GAIYCGFKINHLDLSPRFAGLLISVTNCVANLVGLMAPMVAGHVIDPKPSVENWRIVFYIAAGVF 462

  Fly   528 IAGNFIYLIFASAEEQSW 545
            |.....|.:|||.::| |
  Fly   463 IFTASFYNVFASGKQQ-W 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS10	NP_001285188.1	2A0114euk	63..547	CDD:129972	184/487 (38%)
MFS10	NP_001285188.1	MFS	134..538	CDD:119392	152/407 (37%)
CG6978	NP_572188.1	2A0114euk	38..478	CDD:129972	183/494 (37%)
CG6978	NP_572188.1	MFS	45..473	CDD:119392	176/469 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	270	1.000	Domainoid score	I959
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28615
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	1	0.900	-	-		OOG6_100421
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
	10	9.870