DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS10 and Slc17a2

DIOPT Version :9

Sequence 1:	NP_001285188.1	Gene:	MFS10 / 32263	FlyBaseID:	FBgn0030452	Length:	559	Species:	Drosophila melanogaster
Sequence 2:	XP_038951630.1	Gene:	Slc17a2 / 306950	RGDID:	1308821	Length:	487	Species:	Rattus norvegicus

Alignment Length:	474	Identity:	144/474 - (30%)
Similarity:	254/474 - (53%)	Gaps:	26/474 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 MGFLGFAVVYAMRVNLSVAIVAMVNQTAIPHSNSSVIDTDTCPLPAPHHNGSDPNPQKEGEFVWD 138
            |.|..|.:: ..||:||:||:||||.|......::..:.....|.:....|......:...:.|.
  Rat    33 MHFSNFTMI-TQRVSLSIAIIAMVNSTQHQDPANASAEGPVMNLLSNRSRGIKDFSTRAAVYQWS 96

  Fly   139 EATQGLVLGSFFYGYVLTQVPGGRMAELYGGKKIYGYGVLITAVFTLITPLAAHWDLPLLVLVRI 203
            ..|||::..|..||.:||.:|.|.:|.::|.|:|.|.|:||:::.||.|||||.:.:.|::::|.
  Rat    97 TETQGIIFSSISYGIILTLIPSGYLAGIFGAKQILGAGLLISSLLTLFTPLAADFGVILVIVIRT 161

  Fly   204 LEGMGEGVTYPAMHAMLAHWIPPLERNKFAAIVYAGSNIGTVISMPLAGWLCSLDFLGGWPSAFY 268
            ::||.:|:::.....:.|.|.|||||:|..:|..:|:..|:.|.:.:.|.:..   ..|||..||
  Rat   162 VQGMAQGMSWTGQFTIWAKWAPPLERSKLTSIAGSGAAFGSFIILCVGGLISQ---ALGWPFIFY 223

  Fly   269 IFGLLGILWFIAWMYLVYDKPSDHPRISESEREYIERSLQVQRLINQDLAEAEEEEGQDEVSLRA 333
            |||.:|.:..:.|..::||.|..||.||..|:|||..|:..|                     .:
  Rat   224 IFGSIGCVCCVLWFTMIYDDPMHHPCISVKEKEYITSSVAQQ---------------------SS 267

  Fly   334 PPEEPIPWSSLLTSVPLWAILLTQCGQGWAFYTQLTELPTYMSNILHFDIQSNALLNAVPYLTSW 398
            .|...||..:::..:|||||.:......|.....:|.||||:|.:||.:|:.:.:|:::|::.:.
  Rat   268 SPRRSIPIKAMVRCLPLWAIFMGFFSHFWLCTIIITYLPTYISTVLHVNIRDSGVLSSLPFIAAS 332

  Fly   399 FVGIACSALADWMLARRYISLLNSYKLWNTVASVVPSLGLIGIIYVGCDWVWVTFMLAGVGSFGG 463
            ...|....:||::|:|..:||:...||::::..::|||..:.:.:|...::....:|..:.....
  Rat   333 SCTILGGQMADFLLSRNLLSLITVRKLFSSLGLLLPSLCAVALPFVTSSYIATIVLLILIPGTSN 397

  Fly   464 AVYAGNQMNHIALSPRYAGTMYGITNSAANICGFLAPYVIGLIINHRETLTQWHLVFWLAAGLNI 528
            ...:|..:|.:.::||||..:.||:.......|.::....|.:|: :::.:.|..||:|:|.:|:
  Rat   398 LCDSGFIINTLDVAPRYASFLMGISRGFGLTAGIISSTTTGFLIS-QDSESGWRNVFFLSAAVNM 461

  Fly   529 AGNFIYLIFASAEEQSWSK 547
            .|...||||..||.|:|:|
  Rat   462 FGLIFYLIFGQAEIQNWAK 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS10	NP_001285188.1	2A0114euk	63..547	CDD:129972	143/472 (30%)
MFS10	NP_001285188.1	MFS	134..538	CDD:119392	122/403 (30%)
Slc17a2	XP_038951630.1	MFS_SLC17	30..471	CDD:340876	138/463 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810