DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS10 and SPAC11D3.18c

DIOPT Version :9

Sequence 1:	NP_001285188.1	Gene:	MFS10 / 32263	FlyBaseID:	FBgn0030452	Length:	559	Species:	Drosophila melanogaster
Sequence 2:	NP_001342807.1	Gene:	SPAC11D3.18c / 2543005	PomBaseID:	SPAC11D3.18c	Length:	498	Species:	Schizosaccharomyces pombe

Alignment Length:	568	Identity:	98/568 - (17%)
Similarity:	183/568 - (32%)	Gaps:	186/568 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 DDEREAFCSG-ERPLIRSSGAAEENHG------CGPKTRH---------IFGFMGFLGFAVVYAM 85
            |||...:.|. .:..::::.:.:.::|      ..||...         |...:||| :.:.:..
pombe    12 DDEHSIYASEINKEKLQNTASPDVDYGDTASLKIDPKVEKKLLLKMDLVISPIIGFL-YLMAFLD 75

  Fly    86 RVNLSVAIVAMVNQTAIPHSNSSVIDTDTCPLPAPHHNGSDPNPQKEGEFVWDEATQGLVLGSFF 150
            |.|:..|.||.:              |:...|.....|                    :.:..|:
pombe    76 RSNIGNAAVAGM--------------TEALSLYGERLN--------------------VAVSIFY 106

  Fly   151 YGYVLTQVPGGRMAELYGGKKIYGYGVLITAVFTLITPLAAHWDLPL-----------LVLVRIL 204
            ..|:|.:.|...:.     |:|....:|....|.        |.:.:           |:..|::
pombe   107 VLYILVETPSVVLV-----KRIKASRMLAFISFA--------WSMTVLFSGFMSSYGGLIATRLI 158

  Fly   205 EGMGEGVTYPAMHAMLAHWIPPLERNKFAAIVYAGSNIGTVISMPLAGWLCSLDFLG---GWPSA 266
            .|:.||..:||::..|.......|:.:..:.::|.:.:..... .|..:.......|   ||...
pombe   159 LGLLEGCLFPALNLYLTTHYTRKEQCQRLSYLFASAGLAGAFG-GLFAYALEQVHAGNKEGWQWI 222

  Fly   267 FYIFGLLGILWFIAWMYLVYDKPSDHPRISESEREYIERSLQVQRLINQDLAEAEEEEGQDEVSL 331
            :.:.||:..:.....::.:.||..:...::..|||.        .:|.:|            ::.
pombe   223 YIVEGLVSFIGVPLCLFALPDKMENAWFLTREEREV--------AIIRRD------------INA 267

  Fly   332 RAPPEEPIPWSSL---LTSVPLWAILLTQCGQGWAFYTQLTELPTYMSNILHFDIQSNALLNAVP 393
            |...|:...||.:   .....::....:|.......|...:.||..:..:....:|:|
pombe   268 RYHGEQHFEWSEVRKAFKDPKVYVSATSQFCADMVLYGFSSFLPVIIKGLGFVGLQTN------- 325

  Fly   394 YLT--SWFVGIACSALADWMLAR---RYISLLNSYKLWNTVASVVPSLGLI-------------- 439
            |:|  .:..|:.......|:..|   |.:.|::        ||.|.::|.|
pombe   326 YMTIPVYIAGVISFLFVAWLSDRTQLRAVYLIS--------ASTVVAVGYIIMLASDSNAAKYTA 382

  Fly   440 -GIIYVGCDWVWVTFMLAGVGSFGGAVYAGNQMNHIALSPRYAG-----TMYGITNSAANICGFL 498
             .||.:||                   |.|..:|...|:...||     |..||..:.||..|.:
pombe   383 TYIIAIGC-------------------YIGPGLNLGWLNNNVAGHYKRATAIGIQQTLANSSGIV 428

  Fly   499 A----------PYVIGLIINHRETLTQWHLVFWLAAGLNIAGNFIYLI 536
            |          .|::|    :..||           |..|.|...|::
pombe   429 AGQIYRSKNAPKYILG----NAFTL-----------GCVIVGGLAYVV 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS10	NP_001285188.1	2A0114euk	63..547	CDD:129972	93/535 (17%)
MFS10	NP_001285188.1	MFS	134..538	CDD:119392	79/455 (17%)
SPAC11D3.18c	NP_001342807.1	UhpC	68..461	CDD:332119	88/510 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050