DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MFS10 and mfs2

DIOPT Version :9

Sequence 1:	NP_001285188.1	Gene:	MFS10 / 32263	FlyBaseID:	FBgn0030452	Length:	559	Species:	Drosophila melanogaster
Sequence 2:	NP_592802.1	Gene:	mfs2 / 2542991	PomBaseID:	SPAC11D3.05	Length:	546	Species:	Schizosaccharomyces pombe

Alignment Length:	536	Identity:	97/536 - (18%)
Similarity:	184/536 - (34%)	Gaps:	169/536 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 YAMRVNLSVAIVAMVNQTAIPHSNSSVIDTDTCPLPAPHHNGSDPNPQKEGEFVWDEATQGLVLG 147
            |...:.:.|:::.:|...|....:|.:||.      |...:.|.|..               .||
pombe   104 YKWWIVIQVSVITIVVTFASSVYSSGIIDI------ASELHSSIPVS---------------TLG 147

  Fly   148 S--FFYGYVLTQVPGGRMAELYGGKKIYGYGVLITAVFTLITPLAAH--WDLPLLVLVRILEGMG 208
            |  |..|:.:..:|...::::||...||...:||..:|. :....||  |   .|.:||..:|:.
pombe   148 SCTFLVGFGVGSLPFAPLSDIYGRFIIYFVTLLIFTIFQ-VGGGCAHNVW---TLAIVRFFQGVF 208

  Fly   209 EGVTYPAMHAMLAHWIPPLERN----KFAAIVYAGSNIGTVISMPLAGWLCSLDFLGGWPSAFYI 269
            ...........::....|::|.    .|....|.|..||     |:.|...:..:| .|...|:|
pombe   209 GSTPLANAGGTISDLFTPVQRTYVLPGFCTFPYLGPIIG-----PIIGDFITQSYL-EWRWTFWI 267

  Fly   270 FGLLGILW---FIAWMYLVYDKPSDH-PRISESEREYIERSLQVQRLINQDLAEAEEEEGQDEVS 330
                .::|   .|.::::.:  |..| ..|.:.:.:|:.::..     |.......|.|...:.:
pombe   268 ----NMIWAAAVIVFVFIFF--PETHEDTILDYKAKYLRKTTG-----NTAYYTIHERERDPKNA 321

  Fly   331 LRAPPEEPIPWSSLLTSVPLWAILLTQCGQGWAFYTQLTELPTYMSNILHFDIQSNALLNAVPYL 395
            :.....:.:   ||:.:.|     :..|     |...||.:  |:.|.::|:        ..|.:
pombe   322 MIQAATQAV---SLIFTEP-----IVVC-----FTLYLTVV--YIINYINFE--------GYPIV 363

  Fly   396 TSWF---------------VGIACSALADWMLARRYISLLNSYKLWNTVASVVPSLGLIGIIYVG 445
            .:.:               |||.|:.|....:...|:.:   .|..|.|  :.|...|.. :::|
pombe   364 FAKYGFNKGEQGLSFIGVGVGIVCAGLCTPFIYWHYLKV---NKKRNGV--ICPEDRLYP-LFIG 422

  Fly   446 C----------DWV-------WVTFMLAGVGSFGGAV---------YAGNQMNHIALSPRYAGTM 484
            |          .|.       |:..::|. ..||.::         |..:...|:|.|...|.|:
pombe   423 CFLLPISMFWFAWTCYPHHIHWIVPIIAS-AFFGFSLLIVFFVSYNYIIDSYQHMAPSALAAATL 486

  Fly   485 YGITNS------------------AANICGFLAPYVIGLIINHRETLTQWHLVFWLAAGLNIAGN 531
            ...:.|                  |.::.||::..::.:                         .
pombe   487 VRYSASGGISMVARPMYLNLGDHWATSVLGFISVAMVPI-------------------------P 526

  Fly   532 FIYLIFASAEEQSWSK 547
            ||:..|..: .::|||
pombe   527 FIFYRFGKS-IRAWSK 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS10	NP_001285188.1	2A0114euk	63..547	CDD:129972	95/534 (18%)
MFS10	NP_001285188.1	MFS	134..538	CDD:119392	83/474 (18%)
mfs2	NP_592802.1	MFS	109..530	CDD:119392	92/517 (18%)
mfs2	NP_592802.1	MFS_1	112..493	CDD:284993	86/452 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000