Protein Alignment MFS10 and SLC37A4

DIOPT Version :10

• Sequence 1: NP_572857.1
• Gene: MFS10 / 32263
• FlyBaseID: FBgn0030452
• Length: 559
• Species: Drosophila melanogaster
• Sequence 2: NP_001157750.1
• Gene: SLC37A4 / 2542
• HGNCID: 4061
• Length: 451
• Species: Homo sapiens
• Alignment Length: 499
• Identity: 96/499 - (19%)
• Similarity: 176/499 - (35%)
• Gaps: 134/499 - (26%)

  Fly    70 IFGFMGFLGFAVVYAMRVNLSVAIVAMVNQTAIPHSNSSVIDTDTCPLPAPHHNGSDPNPQKEGE 134
            ||..| |.|:::.|..|...|..:.::|.:  ||      :|.|..
Human    13 IFSAM-FGGYSLYYFNRKTFSFVMPSLVEE--IP------LDKDDL------------------- 49

  Fly   135 FVWDEATQGLVLGSFFYGYVLTQVPGGRMAELYGGKKIYGYGVLITAVFTLITPLAAHWD--LPL 197
                    |.:..|....|.:::...|.:::....:.::..|:|:..:..:...    |.  :|:
Human    50 --------GFITSSQSAAYAISKFVSGVLSDQMSARWLFSSGLLLVGLVNIFFA----WSSTVPV 102

  Fly   198 LVLVRILEGMGEGVTYPAMHAMLAHWIPPLERNKFAAIVYAGSNIGTVISMPLAGWLCSLDFLGG 262
            ...:..|.|:.:|:.:|....:|..|..|.:...:.||:....|:...:. |:...:.:..:  .
Human   103 FAALWFLNGLAQGLGWPPCGKVLRKWFEPSQFGTWWAILSTSMNLAGGLG-PILATILAQSY--S 164

  Fly   263 WPSAFYIFGLLGILWFIAWMYLVYDKPSDHPRISESEREYIERSLQVQRLINQDLAEAEEEEG-- 325
            |.|...:.|.|.::.....:.|::::|:|                  ..|.|.|...:|.::|
Human   165 WRSTLALSGALCVVVSFLCLLLIHNEPAD------------------VGLRNLDPMPSEGKKGSL 211

  Fly   326 QDEVSLRAPPEEPIPWSSLLTSVPLWAIL--------LTQCGQGWAFYTQLTELPTYMSNILHFD 382
            ::|.:|:          .||.|..||.:.        :..|...|..:..:.|
Human   212 KEESTLQ----------ELLLSPYLWVLSTGYLVVFGVKTCCTDWGQFFLIQE------------ 254

  Fly   383 IQSNALLNAVPYLTSWFVG-----IACSALADWMLARRYISLLNSYK---LWNTVASVVPSLGLI 439
             :..:.|....|:::..||     ||...|:|..:|:..:|...:.:   |...:|.:..|:.|.
Human   255 -KGQSALVGSSYMSALEVGGLVGSIAAGYLSDRAMAKAGLSNYGNPRHGLLLFMMAGMTVSMYLF 318

  Fly   440 GIIYVGCD-------WVWVTFMLAGVGSFG---------GAVYAGNQMNHIAL---------SPR 479
            .:. |..|       |......||.:..|.         |||:..:....|||         .|.
Human   319 RVT-VTSDSPKDVAFWTLALHPLAELTGFTEHELWILVLGAVFGFSSYGPIALFGVIANESAPPN 382

  Fly   480 YAGTMYGITNSAANICGFLAPYVIGLIINHRETLTQWHLVFWLA 523
            ..||.:.|....||:.||||......|..|    ..|...||:|
Human   383 LCGTSHAIVGLMANVGGFLAGLPFSTIAKH----YSWSTAFWVA 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS10	NP_572857.1	MFS_SLC17	73..538	CDD:340876	94/496 (19%)
SLC37A4	NP_001157750.1	MFS_SLC37A4	10..439	CDD:340901	96/499 (19%)