DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MFS10 and SPBPB10D8.01

DIOPT Version :9

Sequence 1:	NP_001285188.1	Gene:	MFS10 / 32263	FlyBaseID:	FBgn0030452	Length:	559	Species:	Drosophila melanogaster
Sequence 2:	NP_595045.1	Gene:	SPBPB10D8.01 / 2541399	PomBaseID:	SPBPB10D8.01	Length:	552	Species:	Schizosaccharomyces pombe

Alignment Length:	568	Identity:	118/568 - (20%)
Similarity:	220/568 - (38%)	Gaps:	143/568 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 PHKWTDESRDASCYYDPSTSSNSSASAERSDDEAD----DEREAFCSGERPLIRSSGAAEENHGC 63
            |.::.|:.:.   |:....:|:.|.|:.:|..:..    ||..:|....:.|...:...::.
pombe    22 PKEYVDKEKG---YFPHVITSHISKSSSQSHPDVSNAVLDETFSFMQEAKDLEPLTPKQDKR--- 80

  Fly    64 GPKTRHIFGFMGFLGFAVVYAMRVNLSVA-IVAMVNQTAIPHSNSSVIDTDTCPLPAPHHNGSDP 127
                         |.:.:.:.:.|.|.:. ::..:::..:.:|:...:..||      |.|.:..
pombe    81 -------------LRWKLYFTVLVMLMILDMMLYIDKATLSYSSILGLFEDT------HINSNQY 126

  Fly   128 NPQKEGEFVWDEATQGLVLGSFFY-GYVLTQVPGGRMAELYGGKKIYGYGVLITAVFTLITPL-A 190
            |.                :.:.|| |:|:.|:||..:.:.:...|   :....||::|:|..| .
pombe   127 ND----------------INTLFYVGFVIGQIPGHMLLQRFPVSK---FVAASTALWTIIIFLHC 172

  Fly   191 AHWDLPLLVLVRILEGMGEGVTYPAMHAMLAHWIPPLER---NKFAAIVYAGSNIGTVISMPLAG 252
            |.::...|:.:|...|:.|....|.|.|.:..:.|..|:   ..|..|...|.||.       ||
pombe   173 AAYNFSGLMALRFFLGLVESSLLPTMEATIGMFFPHSEQALLQPFFYISCYGCNIP-------AG 230

  Fly   253 WLC-----SLDFLGGWPSAFYIFGLLGILWFIA-WMYLVY-DKPSDHPRISESEREY-IERSLQV 309
            ::.     :.:.:..|.....|.|  ||.:|:. .::..| |..|....:::.||.| ::|   |
pombe   231 FIAYGVQYAKNTISPWKLFMIIVG--GITFFLTIGLFFYYPDNTSTARFLTKKERLYTVDR---V 290

  Fly   310 QRLINQDLAEAEEEEGQDEVSLRAPPEEPIPW-------------------SSLLTSVPLWAILL 355
            :|..:..:.....::.|...:|:    :|:.|                   :.|.||:.:..:..
pombe   291 RRSNHSGIESKTFKKYQVIEALK----DPVTWLFTFHVFCNQLSNNLAYQQNLLFTSLNVSDLNS 351

  Fly   356 TQCGQGWAFYTQLTE-LPTYMSNILHFDIQSNALLNAVPYLTSWFVGIACSALADWMLARRYISL 419
            |..|...|.|..::. :.|||.:::.   ..:|...|:.|:.|...||||.|:: |
pombe   352 TLVGVASAGYNCVSAIIATYMMSVIK---NQSAFHGAIWYIPSIAGGIACVAMS-W--------- 403

  Fly   420 LNSYKLWNTVASVVPS-LGLIGIIYVGCDWVWVTFMLAG------------VGSFGGAVYAGNQM 471
              .:|:....|.::.| .|:..||.:|    |.|...||            :| :..|...|.||
pombe   404 --DHKIGELAAIIIASNFGIPFIISLG----WTTASCAGYTKKLTRGVMFMIG-YAIANIIGPQM 461

  Fly   472 NHIALSPRYAGTMYGITNSAANICGFLAPYVIGLIINHRETLTQWHLV 519
            .....:|||    |........|...::|:|: |||       :|.||
pombe   462 WQSRDAPRY----YPAWIVQIVIAWSVSPFVL-LII-------RWILV 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS10	NP_001285188.1	2A0114euk	63..547	CDD:129972	107/504 (21%)
MFS10	NP_001285188.1	MFS	134..538	CDD:119392	98/432 (23%)
SPBPB10D8.01	NP_595045.1	MFS	90..492	CDD:119392	101/467 (22%)
SPBPB10D8.01	NP_595045.1	2A0114	101..497	CDD:273326	102/468 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050