DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS10 and SPCC417.10

DIOPT Version :9

Sequence 1:	NP_001285188.1	Gene:	MFS10 / 32263	FlyBaseID:	FBgn0030452	Length:	559	Species:	Drosophila melanogaster
Sequence 2:	NP_588287.1	Gene:	SPCC417.10 / 2539419	PomBaseID:	SPCC417.10	Length:	508	Species:	Schizosaccharomyces pombe

Alignment Length:	525	Identity:	108/525 - (20%)
Similarity:	187/525 - (35%)	Gaps:	146/525 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 DEADDEREAFCSGERPLIRSSGAAEENHGCGPKTRHIFGFMGFLGFAVVYAMRVNLSVAIVAMVN 98
            ||.|.|.      ||.|:|.....            ||..|     .:||.         :..::
pombe    47 DEIDPET------ERRLVRKIDCT------------IFPVM-----CLVYC---------IQFLD 79

  Fly    99 QTAIPHSNSSVIDTDTCPLPAPHHNGSDPNPQKEGE-FVWDEATQGLVLGSFFY-GYVLTQVPGG 161
            :|    |||..:..           |...:.:.||: :.|.        |:.|| ||::.:.|..
pombe    80 KT----SNSYAVIM-----------GLKEDLKMEGQMYSWS--------GTAFYLGYLVFEFPAS 121

  Fly   162 RMAELYGGKK-------IYGYGVLITAVFTLITPLAAHWDLPLLVLVRILEGMGEGVTYPAMHAM 219
            .:.:.:...|       |:|:.:.:|:|.          :.|..:.:|:|.||.|....|....:
pombe   122 LLLQRFPLSKTLCVFLVIWGFLLCMTSVA----------NYPGFIALRVLLGMMESAASPGFILL 176

  Fly   220 LAHWIPPLERNKFAAIVYAGSNIGTVISMPLAGWLCSLDFL--GGWPSAFYIFGLLGILWFIAWM 282
            .|.|....|:....::..|.:.:|.::...:|..|.....|  .||...|.|.|:|.|......:
pombe   177 TAQWYKRSEQQLRTSVWVAFNGLGQILGSCMAYGLAKRTSLPMRGWKLIFIICGVLAIFLGFVIL 241

  Fly   283 YLVYDKPSDHPRISESEREYIERSLQVQRLINQDLAEAEEEEGQDEVSLRAPPEEPI---PW--- 341
            .:|.|.|.....::|.:|:.:.:.|:..:          :..|.:...|....|..:   .|
pombe   242 AVVPDNPFKAWFLTEEDRKLVVKRLRANK----------QGVGNNHFKLYQFKETMLDIRTWIMF 296

  Fly   342 -SSLLTSVP-----LWAILLTQCGQGW-AFYTQLTELPT------------YMSNILHFDIQSNA 387
             ||:|.::|     .::.||.:...|: ...|.|..||.            ::|..:|..:....
pombe   297 VSSVLLNIPNGGIGTFSSLLIKGTMGYDTLQTLLMGLPAGACEFGGLIAFGFLSLFIHKRMVLAT 361

  Fly   388 LLNAVPYLTSWFVGIACSALADWMLARRYI------SLLNSYKLWNTVASVVPSLGLIGIIYVGC 446
            :...:..:.|..:..|....|  .||..|:      :::..:.:.::.||.......:|:||
pombe   362 ITTCIALIGSCLLSFAGPPRA--QLAGYYLLMVSPGAMIVMFAIISSNASGYTKKVTVGVIY--- 421

  Fly   447 DWVWVTFMLAG--VGSFGGAVYAGNQMNHIALSPRY---AGTMYGITNSAANICGFLAPYVIGLI 506
                    |.|  ||:.     .|.|....|.:|.|   ..||.|.  .||.:..|.|.|    .
pombe   422 --------LIGYCVGNL-----IGPQTFKAADAPEYMPAKNTMVGC--YAATLVTFPALY----Y 467

  Fly   507 INHRE 511
            :|.||
pombe   468 VNWRE 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS10	NP_001285188.1	2A0114euk	63..547	CDD:129972	100/496 (20%)
MFS10	NP_001285188.1	MFS	134..538	CDD:119392	88/425 (21%)
SPCC417.10	NP_588287.1	MFS	66..436	CDD:119392	85/444 (19%)
SPCC417.10	NP_588287.1	2A0114	71..468	CDD:273326	94/472 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
TreeFam	0	0.000	Not matched by this tool.
	5	4.960