DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS10 and SPCC757.13

DIOPT Version :9

Sequence 1:	NP_001285188.1	Gene:	MFS10 / 32263	FlyBaseID:	FBgn0030452	Length:	559	Species:	Drosophila melanogaster
Sequence 2:	NP_587688.1	Gene:	SPCC757.13 / 2539039	PomBaseID:	SPCC757.13	Length:	522	Species:	Schizosaccharomyces pombe

Alignment Length:	552	Identity:	110/552 - (19%)
Similarity:	205/552 - (37%)	Gaps:	111/552 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 TSSNSSASA----ERSDDEADDEREAFCSGE-RPLIRSSGAAEENHGCGPKTRHIFGFMGFLGFA 80
            ||..||.|:    |:.....:|.:.:|..|| :.|..:.|.|:      ...:.:.....|. :.
pombe     5 TSRVSSRSSHELTEKKSGVTNDFKNSFEVGEVKRLPDAEGTAD------AVAQELLADDDFT-YT 62

  Fly    81 VVYAMRVNLSVAIVAM-----------VNQTAIPHSNSSVIDTDTCPLPAPHHNGSDPNPQKEGE 134
            ...|.||...:.:|.|           :::||:.::....:.|||      |.:|.
pombe    63 AKEARRVLWKIDLVMMPVMCITYMIQYLDKTALSYAALYGMKTDT------HIDGH--------- 112

  Fly   135 FVWDEATQGLVLGSFFYGYVLTQVPGGRMAELYGGKKIYGYGVLITAVF---TLITPLAAHWDLP 196
                  |...:...|:.||::.|.|...:.:    |....|.:... ||   .::..:||..:.|
pombe   113 ------TYSSMTTLFYAGYLVAQYPAAILMQ----KCRLSYFIFCN-VFLWSAMVCLMAACRNGP 166

  Fly   197 LLVLVRILEGMGEGVTYPAMHAMLAHWIPPLERNKFAAIVYAGSNIGTVISMPLAGWLCSL-DFL 260
            .|:.:|.|.|:.|....||...:.|.|....|:.......||.:.|..:|...|:..|..: ..:
pombe   167 SLLGLRFLAGIFEASITPAFINITAMWYRREEQPMRTLCWYAFNGIAQIIGSILSYGLGHIHGKV 231

  Fly   261 GGWPSAFYIFGLLGILWFIAWMYLVYDKPSDHPRI----SESEREYIERSLQVQRLINQDLAEAE 321
            ..|...|.:.||:.:.|.:.::::    ||:..:.    |..:|..:||       :..:....|
pombe   232 ASWRYVFIVIGLMSLGWGVVFVFI----PSNPSKARFLSSREKRIALER-------VRDNRTGLE 285

  Fly   322 EEEGQDEVSLRAPPEEPIPWSSLLTSVPLWAILLTQCGQGWAFYTQLTELPTYMSNILHFDIQSN 386
            .::.:.:.:..|..:..:...:|.|.|    .::|. |.| .|.|.:.:...|  |.||..: .|
pombe   286 NKQFKWKHAYEAFLDPQVIMITLFTGV----CMITN-GIG-VFSTLIIKGLGY--NELHSAV-LN 341

  Fly   387 ALLNAVPYLTSWFVGIACSALADWMLA----RRYISLLNSYKLWNTVASVVPSLGLIGIIYVGCD 447
            ..|.|:.....:..|:.|....:..|.    ...::|.....:|. :....|...|:|:.:.
pombe   342 MPLGAIEVAAMFISGVLCKVFKNGRLLIGVFMNCLTLAGCLMIWK-IPDSNPYGRLVGVWFT--- 402

  Fly   448 WVWVTFMLAGVGSFGGAVYAGNQMNHIALSPRYAGTMYGITNSAANI-------CGFLAPYVIG- 504
             :||....|.:.|...:..||.....:.     :.|:: :..|..||       .|....|:.|
pombe   403 -MWVPASSALLLSLISSNVAGYTKKTVT-----SATVF-VFYSVGNIVSPQLFKSGQTPEYIEGI 460

  Fly   505 --LIINHRETLTQWHLVFWLAAGLNIAGNFIY 534
              :|::         |...:|....:.|.:||
pombe   461 QAMIVS---------LCIIIAIAFVLTGYYIY 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS10	NP_001285188.1	2A0114euk	63..547	CDD:129972	97/505 (19%)
MFS10	NP_001285188.1	MFS	134..538	CDD:119392	84/423 (20%)
SPCC757.13	NP_587688.1	MFS	80..477	CDD:119392	88/462 (19%)
SPCC757.13	NP_587688.1	2A0114	83..478	CDD:273326	88/460 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X142
TreeFam	0	0.000	Not matched by this tool.
	4	4.050